5 citations
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July 2018 in “Pediatrics” This case report describes a previously healthy 3-year-old girl who developed scurvy symptoms not directly linked to vitamin C dietary deficiency, highlighting the potential for misdiagnosis in similar cases.
1 citations
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November 2024 in “AME Medical Journal” In this case study, scurvy was diagnosed in a middle-aged man on hemodialysis with food insecurity and undetectable vitamin C levels, highlighting the diverse risk factors and persistent challenges in managing vitamin C deficiency among patients with complex medical and social issues.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this N=1 case study, a long-term zero-carbohydrate diet adult male experienced an increase in fasting plasma ascorbic acid from 0.1 mg/dL to 2.0 mg/dL within two months of daily 1 g vitamin C supplementation, along with subjective health improvements.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this N=1 case study, researchers observed that a 1 g daily dose of vitamin C successfully elevated plasma vitamin C levels in an adult male following a zero-carbohydrate diet, with reported improvements in some health parameters but no gastrointestinal side effects.
December 2025 in “Frontiers in Nutrition” This review suggests that although hydrolyzed collagen peptides with certain supplements may improve skin elasticity and joint function, evidence for collagen's anti-aging and regenerative benefits remains inconsistent.
37 citations
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June 2018 in “Clinical and Experimental Medicine” This study found that patients with alopecia areata had significant systemic inflammation and vitamin D deficiency, with both conditions more pronounced as disease severity increased.
13 citations
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February 2020 in “CHEST Journal” This case report observed that pulmonary arterial hypertension in a man with severe vitamin C deficiency resolved after vitamin C supplementation, suggesting a potential role of vitamin C in managing this condition.
5 citations
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January 2012 in “Indian Journal of Dermatology Venereology and Leprology” Werner's syndrome causes early aging and increases cancer risk, requiring early diagnosis and symptom management.
70 citations
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June 2010 in “Clinics in Dermatology” This review discusses how changes in hair and skin may indicate underlying vitamin deficiencies and emphasizes the need to identify populations at risk for these deficiencies; it reports no new results.
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January 2014 in “Reactions Weekly” A woman had nausea and constipation from iron pills taken for hair loss due to low iron.
July 2024 in “Brazilian Journal of Clinical Medicine and Review” This review found that hair loss is common in women after bariatric surgery, linked to nutritional deficiencies and rapid weight loss, highlighting the need for further research and nutrient monitoring.
4 citations
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March 2006 in “Journal of renal nutrition” This study found that hemodialysis patients taking water-soluble vitamins had a 16% lower mortality risk compared to those not taking any, but the specific supplementation needed remains unclear.
June 2021 in “International journal of cosmetics and dermatology” This review found limited support for oral vitamin C and E in treating pigmentary disorders like chloasma, inflammatory conditions, and pressure wounds, with evidence constrained by small, varied studies.
22 citations
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July 2013 in “International Journal of Radiation Biology” In this study, antioxidant vitamins A, C, and E were found to help protect against intestinal damage caused by radiation in rats, with vitamin E being the most effective.
7 citations
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July 2021 in “PubMed” This review assesses the role of vitamins A, B, C, and D in treating dermatologic conditions and highlights promising applications, although further research is required to confirm their efficacy.
1 citations
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March 2020 in “Functional foods in health and disease/Journal of functional foods in health & disease” This study found that OM-X® supplementation effectively prevented adverse biological changes caused by vitamin C deficiency in SMP30/GNL KO mice, improving energy maintenance, antioxidant capacity, and protein synthesis.
November 2025 in “Quality in Sport” This review found that hydrolyzed collagen supplementation, particularly marine collagen, improves skin hydration, elasticity, and density while strengthening hair and nails, especially when paired with vitamin C and trace elements; however, more studies are necessary to evaluate long-term efficacy across different sources and demographics.
October 2025 in “Jurnal Ilmiah Kedokteran dan Kesehatan” This literature review reports that multivitamin supplementation can enhance hair density and quality in people with suboptimal nutritional status but warns that excessive intake of certain vitamins and minerals may cause hair loss.
38 citations
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January 2015 in “Journal of Cosmetic Dermatology” This study found that a 6-month supplementation with omega 3, omega 6, and antioxidants significantly improved hair density and reduced hair loss in women with female pattern hair loss.
36 citations
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May 2021 in “Nutrients” This review summarizes current knowledge on the efficacy of natural molecule supplementation, such as inositols and omega-3 fatty acids, in managing PCOS symptoms but reports no new clinical results.
7 citations
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January 2017 in “Journal of cosmetology & trichology” This article discusses how nutritional and environmental factors, along with antioxidant supplementation, may improve hair growth by mitigating the effects of androgens and reports no new clinical results.
32 citations
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October 2005 in “PubMed” This case study describes a 59-year-old man with scurvy, initially misdiagnosed as leukocytoclastic vasculitis, who showed rapid improvement after vitamin C supplementation; it reviews scurvy's biochemical basis, symptoms, and management.
1 citations
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January 2010 in “Springer eBooks” Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.
95 citations
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February 2018 in “Dermatology and Therapy” This review discusses the role of nutraceuticals in combating skin aging but reports no new clinical results, focusing on their mechanisms of action and potential effectiveness for dermatologists.
June 2026 in “JAAD Case Reports” Scurvy, caused by vitamin C deficiency, can occur in people with restrictive diets and can be diagnosed by twisted hair shafts.
7 citations
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May 2016 in “SpringerPlus” This review suggests that treating endocrine therapy-induced hair loss in breast cancer patients with topical 5-alpha reductase inhibitors and supplements like Vitamin C and omega-3 fatty acids may be effective, but further studies are needed.
3 citations
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February 2017 in “The American journal of medicine” This case report highlights that repletion of various micronutrients, including thiamine, significantly improved heart failure symptoms and cardiac function in a malnourished patient with vitamin deficiencies.
3 citations
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April 2015 in “Cleveland Clinic Journal of Medicine” This case report describes a 22-year-old woman with systemic lupus erythematosus who developed scurvy due to low serum ascorbic acid, despite a diet of white meat and processed foods.
June 2025 in “International Journal of Nutrology” In this systematic review, various nutrients and diets, such as a plant-based diet and supplements like omega-3 fatty acids, were found to impact tissue regeneration, skin health, and wound healing, highlighting the role of nutrient-sensitive signaling pathways in these processes.
January 2023 in “Editora Conhecimento Livre eBooks” A balanced diet with key nutrients and possible supplements can help manage post-COVID-19 symptoms.