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Glossary vertex area

region at the top of the head, often called the crown

The vertex area, also known as the crown area, refers to the top part of the head where the scalp is most prominent. This region is often a focal point in discussions about hair loss, particularly in conditions like androgenetic alopecia, where thinning or balding typically begins at the vertex. Understanding the vertex area is crucial for both diagnosing hair loss patterns and planning treatments such as hair transplants.

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research The 5alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals

17 citations , October 2003 in “Brazilian Journal of Medical and Biological Research”

This study found that SDR5A1 gene expression was similar between hirsute women, normal women, and men, suggesting it may not explain differences in hair growth among these groups.

research Case Report: Paired vertex-occipital assessment reveals donor-area involvement in diffuse unpatterned alopecia

March 2026 in “Frontiers in Medicine”

This study reported that two male patients with diffuse unpatterned alopecia exhibited donor-area involvement in both the vertex and occiput, challenging the assumption of occipital stability for hair transplantation, and showed partial improvement following treatment with oral finasteride and topical minoxidil.

research Predicting the Permanent Safe Donor Area for Hair Transplantation in Koreans with Male Pattern Baldness according to the Position of the Parietal Whorl

14 citations , May 2014 in “Archives of plastic surgery”

This study found that among Korean males with male pattern baldness, hair loss mostly progresses within 6 cm from the parietal whorl towards the occipital side.

research Updated meta-analysis of the relation between heart disease and androgenic alopecia or alopecia areata

2 citations , January 2018 in “Australasian Medical Journal”

This meta-analysis reviewed observational studies and found that androgenic alopecia, particularly in younger men, may be associated with an increased risk of heart disease.

research Co‐localization of alopecia areata and lichen planopilaris in a patient receiving immunosuppressants: A rare case

1 citations , July 2020 in “Journal of cosmetic dermatology”

This case report describes a patient with systemic lupus erythematosus who developed both alopecia areata and lichen planopilaris despite immunosuppressive treatment, suggesting a shared immunopathogenesis between these disorders.

research Letter: Defining the Frontal Area in Hair Restoration Surgery

December 2010 in “Dermatologic Surgery”

The letter discusses a disagreement about the definition of the "frontal area" in hair restoration surgery and questions the effectiveness of treatments like finasteride and minoxidil on this area.

research 50832 Confetti variant of Alopecia Areata: A Single Center Retrospective Study to Describe a Novel Entity

September 2024 in “Journal of the American Academy of Dermatology”

This study found that Latina girls with a unique form of alopecia areata had small, confetti-like hair loss macules that resolved spontaneously within months, suggesting a distinct variant from classic alopecia areata.

research Aesthetic Importance of the Parietal Eminence Area (Posterior Parietal Triangle), an Essential Island of Scalp Requiring Hair Restoration

May 2022 in “Hair transplant forum international”

This study concluded that hair transplants including the parietal eminence area can enhance aesthetic balance and provide indirect cosmetic benefits, even when the vertex is left untreated due to limited donor availability.

research Esthetic importance of parietal eminence area (posterior parietal triangle), an essential island of scalp requiring hair restoration

October 2024 in “Journal of Cutaneous and Aesthetic Surgery”

The authors suggest that during hair transplantation for hair loss, the parietal eminence area should be prioritized along with the mid-scalp to address future noticeable thinning, especially since this area often becomes more conspicuous over time.

research Occipital Hairline: A forgotten area

2 citations , November 2018 in “Journal of Cosmetic Dermatology”

This article discusses the importance of creating a well-designed posterior hairline in hair restoration surgery to enhance the natural appearance of the results but does not present new clinical findings.

research Patient-Based Ratio Method for Permanent Zone Donor Area Calculation in Hair Transplant

June 2024 in “Indian Journal of Plastic Surgery/Indian journal of plastic surgery”

This study found that using a specific ratio method based on the patient's scalp measurements can effectively predict the dimensions of the permanent safe zone for hair transplants, particularly in early stages of androgenetic alopecia, potentially ensuring long-lasting transplant results.

research Fibrosing Alopecia in a Pattern Distribution Localized on Alopecia Androgenetica Areas and Unaffected Scalp

9 citations , November 2004 in “SKINmed Dermatology for the Clinician”

This case report describes a 54-year-old man diagnosed with fibrosing alopecia in a pattern distribution, presenting with follicular inflammatory lesions and scleroatrophy on the scalp.

research A new classification of pattern hair loss that is universal for men and women: Basic and specific (BASP) classification

125 citations , May 2007 in “Journal of The American Academy of Dermatology”

This study describes the development of the BASP classification system, providing a universal and systematic approach for classifying pattern hair loss in both men and women.

research Evaluation of Hair Density and Hair Diameter in the Adult Thai Population Using Quantitative Trichoscopic Analysis

31 citations , February 2020 in “BioMed Research International”

This study found that in the Thai population, hair density varies by scalp location and decreases with age, and that Asians generally have lower hair density compared to Caucasian and African populations.

research Lichen planopilaris in a Latin American (Chilean) population: demographics, clinical profile and treatment experience

19 citations , July 2017 in “Clinical and experimental dermatology”

This study provides one of the first descriptions of the demographic, clinical, and therapeutic characteristics of lichen planopilaris in Chilean adults, reporting that treatment usually reduced or halted disease progression.

research Scalp Biophysical Characteristics in Males with Androgenetic Alopecia: A Comparative Study with Healthy Controls

12 citations , May 2021 in “Clinical Interventions in Aging”

This study found that men with androgenetic alopecia have different scalp biophysical characteristics in androgen-sensitive areas compared to non-sensitive areas and healthy controls.

research Nomenclature Proposal for the Zones and Landmarks of the Balding Scalp

8 citations , April 2001 in “Dermatologic Surgery”

This proposal presents a standardized system for naming areas of the balding scalp to improve communication among hair restoration professionals, defining major regions and introducing new landmarks.

research Hair Regrowth with Cannabidiol (CBD)-rich Hemp Extract – A Case Series

7 citations , April 2021 in “Cannabis”

In this study, topical CBD significantly increased hair count by 93.5% over six months in individuals with androgenetic alopecia, with no adverse effects reported.

research Reproducibility of global photographic assessments of patients with male pattern baldness in a clinical trial with finasteride.

5 citations , January 1995 in “Journal of Investigative Dermatology”

A trial found that using finasteride, a hair growth drug, can be effectively measured by comparing before and after photos.

research Improvement of Hair Graying during a Treatment of Male Pattern Hair Loss Using 1,927-nm Fractionated Thulium Laser Energy and Polydeoxyribonucleotide Injections

3 citations , June 2017 in “Medical lasers”

In this case report, hair graying improved in a patient with male pattern hair loss after combined treatment with thulium laser energy and polydeoxyribonucleotide injections, suggesting potential therapeutic benefits.

research High‐frequency ultrasonography of the scalp: A comparison between androgenetic alopecia and healthy volunteers

1 citations , July 2024 in “Skin Research and Technology”

This study found that patients with androgenetic alopecia had thinner scalp and subcutaneous tissues, narrower and shorter hair follicles, a lower hair follicle count, and fewer color flow signals compared to healthy volunteers, as measured by 22 MHz ultrasound.

research Female Pattern Hair Loss in Female and Male: A Quantitative Trichoscopic Analysis in Chinese Han Patients

1 citations , March 2021 in “Frontiers in Medicine”

In this study, female pattern hair loss in Chinese Han patients was characterized by decreased hair density and shaft diameter, with minor gender differences and the vertex most affected.

research The Predictive Value of Midscalp Hair Density and Terminal Hair Percentage in the Severity Evaluation of FPHL Assessed by Trichoscan in a Sample of Chinese Population

1 citations , December 2022 in “Clinical, Cosmetic and Investigational Dermatology”

In this study, TrichoScan characteristics, particularly hair density and terminal hair percentage in the midscalp, were found to predictively classify female pattern hair loss in a Chinese population.

research Treatment of androgenetic alopecia in transgender people receiving testosterone therapy with sublingual minoxidil: A randomized, double-blind, placebo-controlled clinical trial

May 2026 in “Journal of the American Academy of Dermatology”

In this study, sublingual minoxidil was found to be a safe and effective treatment for increasing hair growth in transgender individuals with mild androgenetic alopecia who are undergoing full-dose testosterone therapy.

research Efficacy of Dr. SKS hair booster serum for the treatment of hair loss in COVID-19 induced persistent telogen effluvium

March 2024 in “International journal of research in medical sciences”

In this study, researchers reported that intradermal injections of Dr. SKS hair booster serum improved hair growth and patient satisfaction in individuals experiencing COVID-19-induced persistent telogen effluvium, with increased benefits observed over six months.

research AN OBSERVATIONAL STUDY TO STANDARDIZE THE DERMOSCOPIC FINDINGS OF NORMAL SCALP AND HAIRS IN MALE

October 2023 in “Asian journal of pharmaceutical and clinical research”

In this study, researchers used trichoscopy to establish standardized findings for normal hair and scalp characteristics in 360 healthy males, noting significant age-related differences in hair diameter variability and identifying potential pathological indicators like colored dots and scarring not present in healthy individuals.

research Orientation of Multi-Hair Follicles in Nonbald Men

May 2006 in “Dermatologic Surgery”

This study found that multi-hair follicles naturally orient perpendicular to the radial line from the crown whirl, suggesting that perpendicular transplantation of grafts could replicate this natural appearance.

research Efficacy of type A botulinum toxin treatment for androgenetic alopecia using ultrasound combined with trichoscopy

June 2024 in “Skin Research and Technology”

In this study, patients with androgenetic alopecia who received type A botulinum toxin treatment showed increased follicle width and length at the vertex and left frontal area over three months, but no significant changes in follicle or hair count compared to the control group.

research Comparison between topical cetirizine with minoxidil versus topical placebo with minoxidil in female androgenetic alopecia: a randomized, double-blind, placebo-controlled study

December 2022 in “Archives of Dermatological Research”

This study found that topical cetirizine increased hair shaft thickness and improved clinical outcomes from the patients' perspective in female androgenetic alopecia compared to minoxidil alone, with similar side effect profiles.

research 32571 Intensive dutasteride mesotherapy protocol (IDMP) with oral minoxidil as an alternative to antiandrogens in AGA. A retrospective analysis of a hair restoration center

September 2022 in “Journal of The American Academy of Dermatology”

In this study, the authors highlight the potential of intradermal microinjections of dutasteride as an adjunctive therapy for androgenetic alopecia, though they note that information on its effectiveness remains limited.