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    Glossary Vascular Endothelial Growth Factor Receptor 2

    regulates blood vessel formation by binding to VEGF

    Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2), also known as KDR, is a protein found on the surface of cells that plays a crucial role in the formation of blood vessels. It binds to VEGF (Vascular Endothelial Growth Factor), triggering a series of signals that promote the growth and maintenance of the vascular system, which is essential for supplying nutrients and oxygen to tissues. This receptor is particularly important in processes like wound healing and the growth of new blood vessels in tumors.

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    1. Use of natural molecules as anti-angiogenic inhibitors for vascular endothelial growth factor receptor Bioinformation · 2012 · 16 citations
    2. Genetic effects of vascular endothelial growth factor and its receptor 2 on feather maturity in three chicken breeds British Poultry Science · 2019 · 1 citations
    3. Naturally Occurring Hair Growth Peptide: Water-Soluble Chicken Egg Yolk Peptides Stimulate Hair Growth Through Induction of Vascular Endothelial Growth Factor Production Journal of Medicinal Food · 2018 · 6 citations
    4. Role of vascular endothelial growth factor in hair follicle biology International Journal of Pathology and Clinical Medicine · 2009
    5. Minoxidil-Induced Hair Growth is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil Journal of Investigative Dermatology · 2001 · 83 citations
    6. Platycladus orientalis Leaf Extract Promotes Hair Growth via Non-Receptor Tyrosine Kinase ACK1 Activation Current Issues in Molecular Biology · 2024
    7. VEGF upregulates VEGF receptor-2 on human outer root sheath cells and stimulates proliferation through ERK pathway Molecular Biology Reports · 2012 · 23 citations
    8. Anti-PDGF receptor β antibody-conjugated squarticles loaded with minoxidil for alopecia treatment by targeting hair follicles and dermal papilla cells Nanomedicine: Nanotechnology, Biology and Medicine · 2015 · 17 citations
    9. GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE Dermatologic Clinics · 1996 · 90 citations
    10. Influence of interleukin‐1α on androgen receptor expression and cytokine secretion by cultured human dermal papilla cells Experimental Dermatology · 2006 · 14 citations
    11. VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro Journal of Dermatological Science · 2013 · 35 citations
    12. VEGFR-2 Is in a State of Activation in Hair Follicles, Sebaceous Glands, Eccrine Sweat Glands, and Epidermis from Human Scalp: An In Situ Immunohistochemistry Study of Phosphorylated VEGFR-2 2019 · 6 citations
    13. The co-expression pattern of VEGFR-2 with indicators related to proliferation, apoptosis, and differentiation of anagen hair follicles Open Life Sciences · 2023
    14. Effects of oleanolic acid on hair growth in mouse dorsal skin mediated via regulation of inflammatory cytokines Journal of Applied Biomedicine · 2023
    15. Engineered Nanovesicles from Fibroblasts Modulate Dermal Papillae Cells In Vitro and Promote Human Hair Follicle Growth Ex Vivo Cells · 2022 · 4 citations
    16. Dexpanthenol Promotes Cell Growth by Preventing Cell Senescence and Apoptosis in Cultured Human Hair Follicle Cells Current Issues in Molecular Biology · 2021 · 13 citations
    17. 721 Efficacy of silybum marianum extract, manganese PCA and lespedeza capitata extract on hair growth and anchorage in human dermal papilla cells 2022
    18. Comment on Malloy (2008) “James Watson tells the inconvenient truth: Faces the consequences” Medical Hypotheses · 2008
    19. Differing responses of human follicular and nonfollicular scalp cells in an in vitro wound healing assay: Effects of estrogen on vascular endothelial growth factor secretion Wound Repair and Regeneration · 2008 · 30 citations
    20. In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach Journal of Investigative Dermatology Symposium Proceedings · 1999 · 30 citations
    21. 1303 Insights gained from a chickens rapid hair development during hatching lead to discovery of hair growth peptide derived from egg yolk Journal of Investigative Dermatology · 2018
    22. Current Therapeutic Approaches to Chronic Central Serous Chorioretinopathy Türk oftalmoloji dergisi · 2019 · 13 citations
    23. The genetics of androgenetic alopecia Clinics in Dermatology · 2001 · 50 citations
    24. [Androgenetic alopecia]. PubMed · 2002
    25. 鍼灸療法에 의한 발모관련 인자들의 발현에 대한 실험적 연구 동의생리병리학회지 · 2011
    26. Adverse Hair Reactions to New Targeted Therapies for Cancer Actas Dermo-Sifiliográficas · 2019 · 1 citations
    27. Gpr54 deletion accelerates hair cycle and hair regeneration EMBO Reports · 2024 · 1 citations
    28. Advances in the Management of Cutaneous Toxicities of Targeted Therapies Seminars in Oncology · 2012 · 42 citations
    29. Microenvironment-Responsive Recombinant Collagen XVII-Based Composite Microneedles for the Treatment of Androgenetic Alopecia Acta Biomaterialia · 2025
    30. Tyrosine Kinase Inhibitors – A Review on Pharmacology, Metabolism and Side Effects Current drug metabolism · 2009 · 508 citations