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The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

Organoids help study and treat genetic diseases, offering personalized medicine and therapy testing.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

A new method helps detect androgen receptor movement in cells, aiding research on hair loss treatments.

mTORC1 activity is important for hair growth and color, and targeting it could help treat hair loss and greying.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

CREB, a protein that can promote cancer traits, is controlled by β-catenin in skin cancer cells.

The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.

The plant hormone auxin activates the TOR pathway, affecting gene expression related to growth and cell size.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Skin problems can be signs of hormone-related disorders and recognizing them early is important for treatment.

The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.