April 2025 in “Journal of Cosmetic Dermatology” This study suggests potential causal associations between certain lipid levels, specifically HDL-C and triglycerides, and alopecia areata, highlighting the importance of lipid management as a therapeutic target.
August 2024 in “Archives of Dermatological Research” This study found that individuals with early-onset androgenetic alopecia showed significant differences in metabolic parameters compared to those with normal-onset alopecia, suggesting a potential link between androgenetic alopecia and metabolic syndrome. However, the nature of this relationship remains uncertain.
June 2024 in “Research Square (Research Square)” In this cross-sectional study, researchers observed that individuals with early-onset androgenetic alopecia showed significant differences in hair growth parameters and metabolic factors compared to those with normal-onset AGA, suggesting a potential association with metabolic syndrome, though more research is needed to clarify this relationship.
February 2024 in “Clinical and Experimental Obstetrics & Gynecology” This study found no significant differences in fat distribution between Thai women with and without polycystic ovary syndrome, though PCOS women with abnormal glucose tolerance showed higher arm fat.
February 2024 in “Heliyon” In this study, AGA patients exhibited distinct lipidomic profiles and higher metabolic syndrome prevalence compared to controls, with certain lipids correlated to key AGA-related factors like DHT, PGD2, and TGF-β1.
January 2022 in “International journal of zoological investigations” In this study, the prevalence of PCOS was reported to be approximately 10% among urban college girls in Chennai, with increased testosterone and decreased progesterone levels observed.
January 2022 in “Indian dermatology online journal” This case report describes a preterm newborn with lamellar ichthyosis, detailing management with acitretin, vitamin D, and emollients, and emphasizes the importance of regular monitoring due to potential adverse effects of long-term retinoid therapy.
October 2018 in “International journal of reproduction, contraception, obstetrics and gynecology” In this study, dyslipidemia was found to be prevalent among young adult women with polycystic ovary syndrome in Port Harcourt, Nigeria, particularly characterized by increased triglycerides and decreased HDL-c levels.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found weak epidemiological associations between male pattern baldness and coronary heart disease, but no significant genetic link, though specific loci shared risks with other conditions.
August 2017 in “International Journal of Research in Dermatology” This study found no significant association between metabolic syndrome and lichen planus, but hypertension, triglycerides, and low HDLC levels were significantly associated with lichen planus.
February 2013 in “Journal of The American Academy of Dermatology” There is no significant link between insulin resistance and certain hair disorders like idiopathic hirsutism and androgenic alopecia.
May 2012 in “15th International & 14th European Congress of Endocrinology” Taking 1mg finasteride tablets for 6 months can lower good cholesterol (HDL) and raise triglycerides in men with hair loss.
August 2011 in “동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine” In this study, treatment with Green tea was found to significantly increase cholesterol and triglyceride levels in sebocyte cells in a dose-dependent manner.
September 2010 in “European Urology Supplements” PSA testing is a reliable method for detecting prostate cancer, and opioids may lower PSA levels, but triglycerides don't affect prostate cancer risk.
January 1981 in “The Journal of Toxicological Sciences” In this study, beagle dogs treated with hydrocortisone 17-butyrate 21-propionate ointment showed various toxic effects, including acne-like skin changes and organ atrophy, which returned to normal after a recovery period.
This study investigated the effects of pathological α-synuclein on sebaceous gland cells in Parkinson's disease, finding that α-synuclein exposure altered cellular differentiation and lipid production, suggesting a potential link between α-synuclein and lipid dysregulation in the skin of PD patients.
August 2026 in “Experimental Dermatology” This study found that a high-fat diet exacerbates hair loss in female mice by increasing oxidative stress and androgen signaling in the skin, and that treatments with antioxidants or antiandrogens may help mitigate this effect.
April 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study, supplementing adult Bichon Frises with 600 mg/kg Omega-3 PUFAs significantly improved their skin health, hair quality, feeding behavior, and metabolic health, compared to a control diet, over six weeks.
December 2025 in “Journal of Skin and Stem Cell” This study found a higher prevalence of lipid abnormalities in individuals with androgenetic alopecia, especially in severe cases, highlighting the need for early screening and treatment to prevent cardiovascular complications.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights that natural hair oils, rich in bioactive compounds, provide multifunctional benefits like reducing protein loss and enhancing shine, but must balance efficacy with safety and sustainability for ongoing cosmetic relevance.
March 2025 in “Journal of Pakistan Association of Dermatologists” This study observed that 62.7% of men with androgenetic alopecia had abnormal blood lipid levels, suggesting the importance of assessing lipid profiles in these individuals for early detection of cardiovascular and metabolic risks.
January 2025 in “International Journal of Trichology” This study reported that among young males with early-onset androgenetic alopecia, there is a high prevalence of metabolic syndrome, particularly in those with severe hair loss, indicating a potential need for early screening and lifestyle changes to reduce cardiovascular risks.
September 2023 in “JEADV Clinical Practice” This study reviewed existing literature and found that androgenic alopecia may be associated with cardiovascular risk factors, while evidence for alopecia areata and cicatricial alopecias is limited and sometimes contradictory.
August 2023 in “Gadua Journal of Pure and Allied Science” This study on diabetic rats reported that Ziziphus spina-christi ethanol leaf extract significantly reduced blood glucose levels and improved liver and kidney function, suggesting possible benefits in managing diabetes symptoms in this animal model.
In this study, a very low-calorie ketogenic diet significantly improved metabolic and hormonal profiles in obese men, but did not significantly enhance most semen parameters except for sperm motility.
January 2022 in “Asian Pacific Journal of Health Sciences” This study assessed the nutritional status of emerging adult women with PCOS and found that while their body measurements were higher than standard, their mean biochemical parameters were within the normal range.
April 2018 in “The Journal of Urology” In this study, men with pre-diabetes seeking treatment for erectile dysfunction had worse hormonal and metabolic profiles and a higher risk of severe erectile dysfunction compared to those without pre-diabetes.
March 2018 in “Vìsnik farmacìï” This study identified flavonoids and phytosterols in a medicated cosmetic cream developed for androgenic alopecia and proposed methods for their identification and quantification.
March 2017 in “Iraqi Journal of Pharmaceutical Sciences” This study found that Iraqi male bodybuilders abusing anabolic androgenic steroids experienced significant changes in sex hormones, liver and kidney function, and lipid profiles compared to non-AAS-using controls.
In this study, women with polycystic ovary syndrome who smoked more had worsened lipid profiles, higher white blood cell counts, and lower prolactin levels compared to non-smokers.