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December 2013 in “ThinkTech (Texas Tech University)” This study found that an 8-week low insulinemic diet significantly improved anthropometric, biochemical, and metabolic measures, binge eating behaviors, and quality of life in women with PCOS.
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May 2013 in “Journal of the Egyptian Women's Dermatologic Society (Print)” In this study, women with androgenetic alopecia showed higher cholesterol levels and carotid artery thickness, suggesting a potential link between female AGA and cardiovascular disease.
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January 2010 in “International journal of medicinal mushrooms” This study found that Ganoderma lucidum fruiting body powder improved cholesterol profiles and hair follicle health in rats exposed to a tumor-promoting agent, suggesting potential chemopreventive properties against skin abnormalities.
November 2025 in “Journal of Cosmetic Dermatology” This study reported that young men with early-onset androgenetic alopecia have a higher prevalence of insulin resistance and metabolic syndrome compared to controls, suggesting that AGA may indicate underlying metabolic disturbances.
July 2025 in “YAKUGAKU ZASSHI” This review highlights that dysbiosis in skin and scalp microbiomes is linked to both atopic dermatitis and androgenetic alopecia, suggesting that microbial composition influences disease progression.
In this study, female patients with Female Pattern Hair Loss were found to have significantly lower serum levels of vitamin D and ferritin, as well as lower total cholesterol and triglyceride levels, compared to healthy controls, suggesting these factors may contribute to the condition's pathogenesis.
September 2025 in “International Journal For Multidisciplinary Research” This study observed that patients with androgenetic alopecia in a western Indian population had a significantly higher prevalence of metabolic syndrome compared to a matched control group, suggesting that individuals with this type of hair loss may benefit from screening for metabolic syndrome.
June 2024 in “International Journal of Cosmetic Science” This study found that various plant oils can penetrate the lipid-rich cell membrane complex of hair, improving its fatigue strength by preventing flaw propagation, with greater penetration observed for oils containing shorter chain lengths and unsaturated fatty acids.
April 2024 in “Cosmetics” Different oils affect hair flexibility and strength, with their impact varying on whether hair is virgin or bleached.
In this study of Andean Ecuadorian women with PCOS, phenotypes A and B were more prevalent and associated with higher risks of insulin resistance, anovulation, and metabolic disorders compared to phenotypes C and D.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, treatment with oral JAK inhibitors was associated with improved disease outcomes in 80.6% of patients with refractory lichen planopilaris over a mean duration of 5 months.
August 2023 in “MOJ women's health” This review discusses the potential role of brown adipose tissue in managing polycystic ovary syndrome and reports no new clinical results; it highlights a need for further research on this therapeutic avenue.
July 2023 in “International Journal of Endocrinology” In this study, researchers observed that Centratherum anthelminticum seed extract effectively reduced cholesterol, triglycerides, insulin resistance, and inflammatory markers, while normalizing hormone levels and oxidative stress markers in rodents with PCOS, suggesting potential benefits for managing the condition.
July 2022 in “Zenodo (CERN European Organization for Nuclear Research)” In this animal study, methanolic extract of *Cordia plathytyrsa* increased testosterone synthesis in male rats but had limited effects on metabolic parameters, while *Piptadeniastrum africanum* raised triglycerides and both extracts did not cause oxidative stress.
July 2022 in “World Journal of Advanced Research and Reviews” This study found that methanolic extract of Cordia plathytyrsa increased testosterone levels in male rats but did not affect other evaluated metabolic parameters.
June 2022 in “Journal of the turkish academy of dermatology” In this study, metabolic syndrome and hypertension were significantly more prevalent in patients with plantar callosities compared to controls, suggesting potential links that warrant further investigation.
January 2021 in “Open MIND” This scoping review aims to explore the impact of hormone therapy on the laboratory profiles of transgender people, identify evidence, and highlight literature gaps, particularly in developing countries.
January 2014 in “Revista del Centro Dermatológico Pascua” This study found no difference in lipid levels between men with and without androgenetic alopecia, suggesting the increased heart disease risk associated with this condition does not solely depend on cholesterol and triglyceride levels.
April 2002 in “Annals of Internal Medicine” This study reported that patients experiencing hypertriglyceridemia during isotretinoin therapy for acne are at higher risk for developing hyperlipidemia and metabolic syndrome.
June 2026 in “International Journal of Research in Medical Sciences” This study compared the adverse effects of baricitinib and methotrexate in treating severe alopecia areata and found baricitinib to have a better safety profile, though it was associated with increased cholesterol, triglyceride, and LDL levels.
This study found that in men with androgenetic alopecia, elevated triglycerides were the only factor consistently associated with the condition, suggesting a potential link between AGA and lipid metabolism, although other hormonal, metabolic, and sleep factors were not significantly different after propensity score matching.
March 2026 in “International Journal of Dermatology” In this study, researchers observed that patients with androgenetic alopecia show differences in scalp microbial communities compared to the general population, including an increase in Cutibacterium acnes, particularly in males, which may interact with lipid and immune pathways to contribute to hair follicle miniaturization.
February 2026 in “International Journal of Advanced Biochemistry Research” This study reports that dogs with dermatoses linked to hypothyroidism displayed a significant incidence of specific haematological and biochemical alterations, such as elevated cholesterol and triglyceride levels and reduced thyroid hormones, compared to healthy dogs, with Labrador Retrievers showing the highest breed predisposition.
January 2026 in “Open Veterinary Journal” This study found that supplementing cat and dog food with PUFA-rich oil improved hair flexibility, brightness, and skin condition, though it also increased serum triglyceride levels, suggesting careful consideration of dosage and fatty acid composition is warranted.
November 2025 in “Journal of Contemporary Medicine” This study observed that women with PCOS exhibited higher levels of triglycerides, fasting insulin, HOMA-IR, total testosterone, DHEAS, and LH/FSH ratio, and lower HDL cholesterol compared to healthy controls, with these markers varying across different PCOS phenotypes.
November 2025 in “Basic and Clinical Andrology” This systematic review and meta-analysis found that male first-degree relatives of women with PCOS have increased rates of metabolic issues, hormonal imbalances, and androgenic features compared to controls, suggesting a male equivalent of PCOS.
August 2025 in “Journal of Medical and Life Science” This case-control study in Missan Province, Iraq, found that married women with PCOS had higher rates of obesity and menstrual irregularities, along with elevated testosterone, LH, and insulin levels, compared to healthy controls, highlighting significant hormonal and metabolic complications.
May 2025 in “International Journal of Trichology” This study found that in males with androgenetic alopecia, greater severity was significantly associated with elevated total cholesterol and triglyceride levels, suggesting a need for cardiovascular risk screening.
April 2025 in “Journal of Clinical Medicine” In this study, women with suspected PCOS who reduced their intake of sweets, fatty red meat, and alcohol for over 6 months showed significantly lower total testosterone levels compared to those who did not, highlighting the benefit of targeted dietary changes on hormonal profiles.
In this case-control study, researchers found that serum apelin-12 levels were significantly higher in acne patients and correlated with acne severity, BMI, insulin resistance, and inflammation, suggesting that managing insulin resistance could be important for acne treatment.