This study observed that women with polycystic ovary syndrome showed hormonal changes and higher post-meal lipemia compared to healthy controls, alongside endothelial dysfunction potentially detectable before insulin resistance.
This study found that men with early-onset androgenic alopecia may be partially resistant to the cardiometabolic benefits of bromocriptine compared to those with normal hair growth.
July 2008 in “International journal of psychophysiology” This retrospective study found that cyproterone acetate, both alone and with estrogens, was safe, well tolerated, and induced modest feminizing effects in late-pubertal transgender female adolescents.
November 2007 in “Neuro-chirurgie/Neurochirurgie” This study reported that treatment with cyproterone acetate alone and then with incremental estrogen doses induced mild feminizing effects in late-pubertal trans-girls, with further feminization observed after adding estrogen.
September 1988 in “Inpharma (Balgowlah)” Retinoids are effective for acne but can cause serious side effects.
September 2018 in “Fertility and Sterility” In this study, researchers observed that overweight Taiwanese women with PCOS who carry the HSD3B1 1245C allele have a significantly higher risk of developing androgenic alopecia compared to those with the wild-type allele.
January 2004 in “Journal of Clinical Dermatology” This study found significant differences in serum total lipid, phospholipid, and triglyceride levels between patients with androgenetic alopecia and those without but no differences in LDL, HDL, or total cholesterol.
December 2022 in “Sri Lanka Journal of Diabetes Endocrinology and Metabolism” This study found a significant association between early onset androgenetic alopecia and metabolic syndrome, with higher prevalence of metabolic risk factors in affected individuals compared to a control group.
December 2021 in “Biomarkers” This study found that men with early-onset male pattern alopecia did not significantly differ from healthy individuals in cardiovascular and metabolic measures, but hsCRP and galectin-3 were linked to cardiovascular risk factors in those with the condition.
September 2022 in “Medical Mycology” This study found that patients with androgenic alopecia exhibited higher levels of Malassezia colonization and altered sebum composition compared to individuals without AGA.
December 2021 in “International Journal of Research in Dermatology” This study found a higher prevalence of metabolic syndrome among young male patients with androgenic alopecia compared to age-matched controls.
June 2021 in “Egyptian Journal of Dermatology and Venereology” This study found that psoriasis, acne, and androgenetic alopecia are associated with an atherogenic lipid profile, suggesting an increased risk of atherosclerosis and cardiovascular disease, especially among psoriasis patients.
February 2019 in “Journal of Pakistan Association of Dermatology” This study found that abnormal serum lipid levels were prevalent among male patients with androgenetic alopecia, with high triglycerides and low HDL observed frequently.
February 2017 in “Clinical dermatology open access journal” This study found a strong association between insulin resistance and early androgenetic alopecia in males, with insulin resistance increasing alongside alopecia severity and influenced by factors like smoking.
October 2022 in “The Journal of Clinical Pharmacology” This study found that men with early-onset androgenic alopecia are less responsive to the cardiometabolic effects of bromocriptine compared to men with normal hair growth.
December 2021 in “Benha Journal of Applied Sciences” This study found that high serum alarin levels were linked to both androgenetic alopecia and metabolic syndrome, increasing with the severity of AGA.
January 2021 in “Menoufia Medical Journal” This study found that patients with early-onset androgenetic alopecia had significantly higher levels of fasting blood sugar, triglycerides, and cholesterol, suggesting an increased risk of developing coronary artery disease.
October 2018 in “International Journal of Research in Dermatology” In this study, androgenetic alopecia patients had a significantly higher prevalence of metabolic syndrome and related metabolic disorders compared to those without the condition.
July 2015 in “Egyptian Journal of Dermatology and Venereology” This study concluded that patients with androgenetic alopecia may have a higher risk of cardiovascular diseases compared to people without this condition.
December 2013 in “Tehran University Medical Journal TUMS Publications” In this study, no significant relationship was found between androgenetic alopecia and hyperlipidemia, but higher levels of cholesterol, LDL, and triglycerides in AGA patients may suggest an increased risk of coronary heart disease.
53 citations
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October 1993 in “Drug Safety” Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
48 citations
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October 2014 in “International Journal of Cardiology” This meta-analysis found that people with alopecia have an increased risk of coronary heart disease and several cardiovascular risk factors compared to those without alopecia.
37 citations
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January 1993 in “Yakugaku zasshi” This study found that a 70% ethanolic extract from Ginkgo biloba leaves promotes hair regrowth in C3H mice.
29 citations
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November 2011 in “Human Fertility” This study reports significant variability in PCOS symptoms across women attending infertility, gynecology, endocrine, and dermatology clinics, highlighting the importance of recognizing diverse presentations and associated health risks like impaired glucose tolerance and diabetes.
18 citations
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July 2001 in “Australian veterinary journal” This case study describes a cat with concurrent cutaneous xanthomas, demodicosis, and dermatophytosis, which suggests potential primary hyperlipidaemia as the underlying cause for its symptoms.
17 citations
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January 2014 in “Journal of Clinical and Diagnostic Research” This study found that patients with oral lichen planus and oral lichenoid reactions have higher levels of serum cholesterol and LDL-C than healthy individuals, suggesting a potential elevated risk for cardiovascular disease.
16 citations
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April 2007 in “Journal of Obstetrics and Gynaecology Research” In this study, serum PSA levels were higher in women with PCOS, suggesting it may serve as a marker for hyperandrogenism in this condition.
14 citations
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May 2013 in “American Journal of Physiology-endocrinology and Metabolism” This study found that mice lacking myelin protein zero-like 3 (Mpzl3) had reduced body weight and adiposity despite increased food intake, which was linked to higher energy expenditure and improved glycemic control.
7 citations
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March 2011 in “Hormone and Metabolic Research” This study found that in PCOS patients, variations in the lipin 1 gene, particularly the intron 1 SNP, may protect against insulin resistance and glucose intolerance, highlighting a potential genetic factor in the disorder's cardiometabolic complications.
5 citations
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February 2021 in “JCPSP. Journal of the College of Physicians & Surgeons Pakistan” This study investigated the relationship between early-onset androgenetic alopecia and metabolic syndrome in younger males, but the abstract does not report specific results.