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    Glossary Transglutaminase 3

    enzyme crucial for skin and hair protein cross-linking

    Transglutaminase 3 (TGM3) is an enzyme that plays a crucial role in the formation and maintenance of the outer layer of the skin and hair follicles. It helps in the cross-linking of proteins, which strengthens the structural integrity of these tissues. Deficiencies or malfunctions in TGM3 can lead to skin disorders and hair loss conditions.

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    Research 30 of 497

    1. Transglutaminase 5 Expression in Human Hair Follicle Journal of Investigative Dermatology · 2005 · 28 citations
    2. Human epidermal transglutaminase. Preparation and properties. Journal of Biological Chemistry · 1976 · 138 citations
    3. The Proximal Promoter of the Human Transglutaminase 3 Gene 1996 · 105 citations
    4. Transglutaminase from Hair Follicle of Guinea Pig Proceedings of the National Academy of Sciences · 1972 · 103 citations
    5. Kinetic Studies with Transglutaminases Journal of Biological Chemistry · 1972 · 91 citations
    6. Identification of a preferred substrate peptide for transglutaminase 3 and detection of <i>in situ</i> activity in skin and hair follicles ˜The œFEBS journal · 2010 · 35 citations
    7. Transglutaminase-3, an esophageal cancer-related gene International Journal of Cancer · 2000 · 32 citations
    8. Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding? 2008 · 30 citations
    9. Transglutaminase 3: The Involvement in Epithelial Differentiation and Cancer Cells · 2020 · 22 citations
    10. Lamellar ichthyosis with pseudoexon activation in the transglutaminase 1 gene Journal of dermatology · 2015 · 10 citations
    11. Transglutaminase Activity Is Conserved in Stratified Epithelia and Skin Appendages of Mammals and Birds International journal of molecular sciences · 2023 · 8 citations
    12. Purification and Calcium Dependence of Transglutaminases from Sheep Hair Follicles Bioscience Biotechnology and Biochemistry · 1997 · 7 citations
    13. Repair of damaged hair protein fiber by jointly using transglutaminase and keratin ScienceAsia · 2021 · 3 citations
    14. Application of Transglutaminase for Hair Revitalization Journal of the Society of Cosmetic Scientists of Korea · 2013 · 3 citations
    15. Transglutaminase-mediated cross-linking in mammalian epidermis 1984 · 3 citations
    16. 130 Dermal IgA deposition targeted against Transglutaminase 3 in Dermatitis herpetiformis risk groups Journal of Investigative Dermatology · 2024
    17. Involvement of Transglutaminase 3 (TG3) in Hair Stiffness Changing with Age by Capture of Zinc 2024
    18. 1329 Transglutaminase 2 deficiency leads to lipid accumulation and reduced autophagy in SZ95 sebocytes 2023
    19. 110 Transglutaminase 2 is a potential regulator of sebocyte maturation 2017
    20. An investigation into the action of transglutaminase on human hair Journal of the Society of Cosmetic Chemists · 1995
    21. Hair Follicle Transglutaminases and the Formation of ε-(γ-Glutamyl) Cross-links 1981
    22. Human Epidermal Transglutaminase Journal of Investigative Dermatology · 1983 · 53 citations
    23. Biochemistry of Transglutaminases and Cross-Linking in the Skin Journal of Investigative Dermatology · 1983 · 57 citations
    24. Epidermal and hair follicle transglutaminases and crosslinking in skin 1984 · 1 citations
    25. Targeted Inactivation of Gh/Tissue Transglutaminase II Journal of Biological Chemistry · 2001 · 288 citations
    26. [Studies on enzyme activities in the hair root in male pattern baldness: glycolytic enzyme, acid hydrolase, transglutaminase and ornithine decarboxylase activities of plucked hair roots]. PubMed · 1985
    27. NIPAL4 mutation c.527C˃A identified in Romanian patients with autosomal recessive congenital ichthyosis Revista română de medicină de laborator · 2016 · 1 citations
    28. Epithelial barrier function: assembly and structural features of the cornified cell envelope BioEssays · 2002 · 425 citations
    29. Apoptosis in human skin development: Morphogenesis, periderm, and stem cells Developmental dynamics · 1994 · 253 citations
    30. The structure of human trichohyalin. Potential multiple roles as a functional EF-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein Journal of Biological Chemistry · 1993 · 161 citations