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    Did you mean Transforming Growth Factor Alpha?
    Glossary Transforming Growth Factor Alpha

    protein involved in cell growth and hair follicle regulation

    Transforming Growth Factor Alpha (TGF-α) is a protein that plays a crucial role in cell growth, proliferation, and differentiation. It binds to the epidermal growth factor receptor (EGFR) on the cell surface, triggering a cascade of cellular processes that can influence tissue development and repair. In the context of hair biology, TGF-α is involved in the regulation of hair follicle development and cycling, and its dysregulation can be associated with conditions like alopecia.

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    1. Transforming growth factor-alpha immunoreactivity during induced hair follicle growth cycles in sheep and ferrets. 1996 · 6 citations
    2. Effects of Epidermal Growth Factor and Transforming Growth Factor on Cultured Hair Follicle Cells from Human Scalp Skin research · 1994
    3. Alopesi areata hastalarında serum interferon-gama, tümör nekrozis faktör-alfa, interlökin-13, interlökin-17 ve transforming growth faktör-beta düzeylerinin değerlendirilmesi 2016
    4. Expression of transforming growth factor-β_1 and tumor necrosis factor-α in mice with radiationinduced pulmonary injury 2010
    5. Cytokines and growth factors influence hair growth in vitro. Possible implications for the pathogenesis and treatment of alopecia areata Archives of Dermatological Research · 1996 · 91 citations
    6. GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE Dermatologic Clinics · 1996 · 90 citations
    7. Endogenous Production of Heparin-Binding EGF-Like Growth Factor During Murine Partial-Thickness Burn Wound Healing Journal of Burn Care & Rehabilitation · 2002 · 70 citations
    8. Growth factors specifically alter hair follicle cell proliferation and collagenolytic activity alone or in combination Differentiation · 1990 · 56 citations
    9. Increment of growth factors in mouse skin treated with non-thermal plasma International journal of medical sciences · 2018 · 18 citations
    10. Collagen Hydrolysate from the Scales of Mozambique Tilapia (Oreochromis mossambicus) Improve Hair and Skin Health by Alleviating Oxidative Stress and Inflammation and Promoting Hair Growth and Extracellular Matrix Factors Marine drugs · 2023 · 2 citations
    11. Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation. Genes & Development · 1991 · 409 citations
    12. An <i>in Vitro</i> Model for the Study of Human Hair Growth Annals of the New York Academy of Sciences · 1991 · 13 citations
    13. Effects of oleanolic acid on hair growth in mouse dorsal skin mediated via regulation of inflammatory cytokines Journal of Applied Biomedicine · 2023
    14. Role of Dermal Factors Involved in Regulating the Melanin and Melanogenesis of Mammalian Melanocytes in Normal and Abnormal Skin International journal of molecular sciences · 2024
    15. Comparative Study of Some Potential Paracrine Factors Produced by Normal and Androgenetic Alopecia Hair Follicles American journal of medical and biological research · 2015
    16. The role of integrin alphavbeta6 in impaired wound healing and hair follicle regeneration 2010
    17. <i>Melandrium firmum</i>Extract Promotes Hair Growth by Modulating 5α-Reductase Activity and Gene Expression in C57BL/6J Mice Annals of Dermatology · 2019 · 2 citations
    18. Formation of actin mesh structures and alpha-smooth muscle actin dynamics in fibroblasts contribute to dermal regeneration in mouse fetus PLoS ONE · 2025 · 1 citations
    19. The Experimental Studies of YangHyulEum Gami-Bang Extracts on the Hair Growth Effect Hanbang an'i'bi'in'hu pibu'gwa haghoeji · 2016 · 1 citations
    20. Regulation of human hair growth: hormones and neuropeptides 프로그램북(구 초록집) · 2016
    21. The epidermis: rising to the surface Current opinion in genetics & development · 1994 · 238 citations
    22. Ectopic Expression of the nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia Developmental biology · 1999 · 69 citations
    23. Epigen Transgenic Mice Develop Enlarged Sebaceous Glands Journal of Investigative Dermatology · 2009 · 33 citations
    24. Biphasic Regulation of HMG-CoA Reductase Expression and Activity during Wound Healing and Its Functional Role in the Control of Keratinocyte Angiogenic and Proliferative Responses Journal of Biological Chemistry · 2008 · 27 citations
    25. Altered expression of intracellular Toll-like receptors in peripheral blood mononuclear cells from patients with alopecia areata BBA clinical · 2016 · 12 citations
    26. RE-ORGA, a Korean Herb Extract, Can Prevent Hair Loss Induced by Dihydrotestosterone in Human Dermal Papilla Cells Annals of Dermatology · 2019 · 4 citations
    27. Treatment of Cultured Sebocytes with an EGFR Inhibitor Does Not Lead to Significant Upregulation of Inflammatory Biomarkers Annals of Dermatology · 2011 · 3 citations
    28. Differences in cell subsets between sun-exposed and unexposed skin: preliminary single-cell sequencing and biological analysis from a single case Frontiers in Medicine · 2024 · 3 citations
    29. RETRACTED: Explore the genetic exposure to alopecia areata Skin Research and Technology · 2024 · 2 citations
    30. News in brief Expert Review of Dermatology · 2010