Dermal stem cells help regenerate hair follicles and heal skin wounds.
1 citations,
January 2023 in “Burns & Trauma” Wnt4 protein makes the outer skin layer thicker in burn wounds by turning on a specific healing pathway and loosening the connections between skin cells.
20 citations,
February 2018 in “Cell transplantation” Cinnamomum osmophloeum leaf extract may help treat hair loss by promoting hair growth and increasing hair cell proliferation.
25 citations,
December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
March 2024 in “Advanced science” A new hydrogel made from human cells improves wound healing by working with immune cells to promote repair.
146 citations,
January 2004 in “Hormones” Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
1 citations,
January 2022 in “Faculty reviews” The best long-lasting results in treating hair loss may be achieved through combination therapy, including treatments like finasteride, minoxidil, and platelet-rich plasma injections.
April 2024 in “International journal of molecular sciences” Dermal factors are crucial in regulating melanin production in skin.
October 2024 in “International Journal of Molecular Sciences” Rosa rugosa extract promotes hair growth and could be a natural treatment for hair loss.
137 citations,
June 2005 in “Climacteric” Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Immune cells are essential for early hair and skin development and healing.
480 citations,
August 2014 in “Nature Biotechnology” Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
August 2024 in “Applied Sciences” Plant extracts may help prevent or reverse hair graying.
December 2022 in “Dermatology and Therapy” Alopecia areata needs more recognition and better treatment access in Latin America to improve patient care and outcomes.
13 citations,
April 2019 in “Actas Dermo-Sifiliográficas” Vitamin D is important for skin health, but more research is needed to understand its full effects and treatment potential.
61 citations,
April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
62 citations,
July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
49 citations,
July 2009 in “Fitoterapia” Essential oils from Chamaecyparis obtusa may help hair grow by increasing a growth-related gene.
13 citations,
December 2017 in “BMC Complementary and Alternative Medicine” The Asian herbal mix with Houttuynia cordata, Perilla frutescens, and green tea helped grow hair in mice.
Crinum asiaticum extract and norgalanthamine may promote hair growth by blocking an enzyme linked to hair loss and a pathway that stops hair growth.
53 citations,
March 2014 in “Growth Hormone & IGF Research” IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.
64 citations,
March 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
78 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.
68 citations,
April 2012 in “Journal of Investigative Dermatology” The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
August 2011 in “Planta Medica” 4-O-methylhonokiol from Magnolia Officinalis may promote hair growth by interfering with TGF-β1 effects in skin cells.
4 citations,
November 2022 in “Nutrients” Cow placenta extract has strong antioxidant effects and can delay skin aging in mice.
Yonnyuniksoogobon-dan, an herbal mix, was found to promote hair growth in mice.
9 citations,
March 2009 in “European Journal of Dermatology” Schisandra nigra extract may help hair grow by stimulating cells and preventing hair follicle damage.
January 2007 in “The Year book of surgery” The mouse model shows potential for understanding and improving scarless wound healing, and Wnt-4 and TGF-β1 play a role in wound healing and scar formation.