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    Glossary Transferrin Saturation

    Transferrin saturation refers to the percentage of transferrin, a protein that binds and transports iron in the bloodstream, that is saturated with iron. It is a crucial indicator of iron metabolism and can be relevant in the context of hair loss, as iron deficiency has been linked to conditions such as telogen effluvium and alopecia. Key distinguishing characteristics include its measurement through serum iron and total iron-binding capacity (TIBC), with normal transferrin saturation levels typically ranging from 20% to 50%. Monitoring transferrin saturation can help identify potential nutritional deficiencies that may contribute to hair thinning or loss.

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    1. Obstructive sleep apnea, low transferrin saturation levels, and male‐pattern baldness International Journal of Dermatology · 2018 · 5 citations
    2. Iron status in diffuse telogen hair loss among women. PubMed · 2009 · 93 citations
    3. Beyond anemia: a comprehensive analysis of iron deficiency symptoms in women and their correlation with biomarkers BMC Women s Health · 2025 · 2 citations
    4. Clinical and Laboratory Characteristics of Individuals Aged ≤17 Years With Homeostatic Iron Regulator (HFE) p.C282Y Homozygosity, a Common Hemochromatosis Genotype Curēus · 2023 · 1 citations
    5. Reticulocyte Hemoglobin Content as a Best Indicator of Iron Deficiency in Female Patients with Diffuse Non-Scarring Hair Loss Biomedical & Pharmacology Journal · 2021 · 1 citations
    6. IRON DEFICIENCY ANEMIA: EPIDEMIOLOGY, PATHOGENESIS, CLINICAL MANIFESTATIONS, AND MODERN TREATMENT APPROACHES Zenodo (CERN European Organization for Nuclear Research) · 2026
    7. IRON DEFICIENCY ANEMIA: EPIDEMIOLOGY, PATHOGENESIS, CLINICAL MANIFESTATIONS, AND MODERN TREATMENT APPROACHES Zenodo (CERN European Organization for Nuclear Research) · 2026
    8. Impact of Iron Deficiency on the Individual 2025
    9. Causes and management of Pica disorder among central Iraqi peoples Polski Merkuriusz Lekarski · 2024
    10. High-Dosed Intravenous Iron Replacement Therapy for Iron Deficiency Anemia Does Not Hinder Drug-Induced Amelioration of Disease Activity in IBD Patients The American Journal of Gastroenterology · 2018
    11. P730 High-dosed intravenous iron replacement therapy does not hinder drug-induced amelioration of disease activity in IBD patients with iron deficiency anaemia Journal of Crohn s and Colitis · 2018
    12. Efficacy of Compound GV-350 with Tricofer® Iron, Cystine and Biotin in the Management of Telogen Effluvium in Women with Iron Deficiency 2025
    13. 851 The role of astrotactin2 in regulating mammalian skin polarity 2017
    14. [Anejaculation caused by haemosiderosis: male infertility in hereditary haemochromatosis]. PubMed · 2007 · 1 citations
    15. IRON DEFICIENCY: AN UNDER-RECOGNIZED PROBLEM IN KIDNEY TRANSPLANTATION. RISKS OF IRON TREATMENT. Transplantation · 2004
    16. P0689 High-dose IV iron safely and effectively treats IBD-associated anaemia regardless of inflammatory activity – real-life evidence from Germany Journal of Crohn s and Colitis · 2026
    17. The overexpression of R-spondin 3 affects hair morphogenesis and hair development along with the formation and maturation of the hair follicle stem cells Frontiers in Physiology · 2024 · 6 citations
    18. Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility1 Biology of Reproduction · 2004 · 35 citations
    19. Epidermal growth factor and transferrin receptor expression in human embryonic and fetal epidermal cells Archives of Dermatological Research · 1990 · 10 citations
    20. Regulatory T cells are required for normal and activin‐promoted wound repair in mice European Journal of Immunology · 2018 · 29 citations
    21. Wnt10b Promotes Differentiation of Mouse Hair Follicle Melanocytes International Journal of Medical Sciences · 2013 · 29 citations
    22. β-Catenin–Dependent Wnt Signaling: A Pathway in Acute Cutaneous Wounding [RETRACTED] Plastic and Reconstructive Surgery · 2018 · 13 citations
    23. Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle PloS one · 2015 · 31 citations
    24. Directed Expression of Keratin 16 to the Progenitor Basal Cells of Transgenic Mouse Skin Delays Skin Maturation The Journal of Cell Biology · 1998 · 79 citations
    25. Early lead exposure and pubertal development in a Mexico City population Environment international · 2019 · 29 citations
    26. PPAR-<i>γ</i> Agonists and Their Role in Primary Cicatricial Alopecia PPAR Research · 2017 · 38 citations
    27. A pair of transmembrane receptors essential for the retention and pigmentation of hair Genesis · 2012 · 11 citations
    28. Regulatory T cells in skin regeneration and wound healing 2023 · 3 citations
    29. Surgical Management of Scarring Alopecia IntechOpen eBooks · 2022
    30. New hyaluronan-based biomatrix for 3-D follicle culture yields functionally competent oocytes Research Square (Research Square) · 2022