Search
for

    Glossary Trametinib

    medication that inhibits MEK protein to treat specific cancers

    Trametinib is a medication used to treat certain types of cancer, specifically melanoma with a BRAF V600E or V600K mutation. It works by inhibiting a protein called MEK, which is part of a pathway that helps cancer cells grow and divide. By blocking this protein, trametinib can slow down or stop the growth of cancer cells.

    Sort by

    Research 30 of 75

    1. Prospective Case Series of Cutaneous Adverse Effects Associated With Dabrafenib and Trametinib Journal of cutaneous medicine and surgery · 2016 · 10 citations
    2. Pustular Eruption in a Patient Treated With Trametinib Pediatric Dermatology · 2025
    3. Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection Cell Host & Microbe · 2016 · 133 citations
    4. Hair and nail adverse events during treatment with targeted therapies for metastatic melanoma 2016 · 32 citations
    5. Cutaneous reactions to targeted therapies in children with CNS tumors: A cross‐sectional study Pediatric Blood & Cancer · 2019 · 16 citations
    6. Dyad of infantile cutaneous and thymic Langerhans cell histiocytosis: Is it rare? Pediatric blood & cancer · 2023
    7. 645 MIG6 is MEK-regulated and affects EGF-induced migration in mutant NRAS melanoma Journal of Investigative Dermatology · 2016
    8. 696 MEK and BRAF inhibitors augment the production and accumulation of sebum in hamster sebocytes Journal of Investigative Dermatology · 2016
    9. Multimodal therapeutic approach for a severe case of kaposiform lymphangiomatosis from procedural interventions to targeted therapies Pediatric Blood & Cancer · 2024 · 1 citations
    10. Hydrogel-Forming Microneedles for Transdermal Drug Delivery Preprints.org · 2023 · 10 citations
    11. Biological therapy in the treatment of melanoma Journal of Mind and Medical Sciences · 2018 · 3 citations
    12. Dermatologic Adverse Events from Cancer Treatments Springer eBooks · 2018 · 2 citations
    13. The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: the Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma Current Dermatology Reports · 2013 · 6 citations
    14. Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails American Journal of Clinical Dermatology · 2018 · 179 citations
    15. Cutaneous reactions to chemotherapeutic drugs and targeted therapy for cancer Journal of the American Academy of Dermatology · 2014 · 88 citations
    16. Drug-induced acne Clinics in Dermatology · 2016 · 52 citations
    17. Alopecia in patients treated with molecularly targeted anticancer therapies Annals of Oncology · 2015 · 44 citations
    18. Pathogenesis and treatment options for chemotherapy‐induced alopecia: a systematic review International Journal of Dermatology · 2018 · 34 citations
    19. Clinical management of cutaneous adverse events in patients on targeted anticancer therapies and immunotherapies: a national consensus statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology Clinical & Translational Oncology · 2018 · 26 citations
    20. Alopecia in Association with Malignancy: A Review American Journal of Clinical Dermatology · 2018 · 26 citations
    21. An antimicrobial microneedle patch promotes functional healing of infected wounds through controlled release of adipose tissue-derived apoptotic vesicles Journal of Nanobiotechnology · 2024 · 10 citations
    22. New small molecules in dermatology: for the autoimmunity, inflammation and beyond Inflammation Research · 2023 · 9 citations
    23. Hormone receptor positive, HER2 negative metastatic breast cancer: Impact of CDK4/6 inhibitors on the current treatment paradigm Asia-Pacific Journal of Clinical Oncology · 2018 · 4 citations
    24. Dermatologic adverse events associated with chemotherapy and targeted anticancer therapy Dermatology Review · 2016 · 4 citations
    25. Cancer Treatments and Alopecia: A Systematic Review Turkiye Klinikleri Journal of Internal Medicine · 2021 · 2 citations
    26. Management of Toxicities of Targeted Therapies Elsevier eBooks · 2018 · 2 citations
    27. Cutaneous Side Effects of Chemotherapy and Radiotherapy 2016 · 2 citations
    28. Adverse Hair Reactions to New Targeted Therapies for Cancer Actas Dermo-Sifiliográficas · 2019 · 1 citations
    29. Graft-versus-host disease with acute hair loss: A distinctive manifestation of chronic graft-versus-host disease Journal of The American Academy of Dermatology · 2016 · 1 citations
    30. Dermoscopy — 4th Conference of the Section of Dermoscopy and Other Skin Imaging Techniques (DiTOS) of the Polish Dermatological Society — Abstracts Forum Dermatologicum · 2026