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    Glossary Trametinib

    medication that inhibits MEK protein to treat specific cancers

    Trametinib is a medication used to treat certain types of cancer, specifically melanoma with a BRAF V600E or V600K mutation. It works by inhibiting a protein called MEK, which is part of a pathway that helps cancer cells grow and divide. By blocking this protein, trametinib can slow down or stop the growth of cancer cells.

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    Research 30 of 72

    1. Prospective Case Series of Cutaneous Adverse Effects Associated With Dabrafenib and Trametinib Journal of cutaneous medicine and surgery · 2016 · 10 citations
    2. Pustular Eruption in a Patient Treated With Trametinib Pediatric Dermatology · 2025
    3. Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection Cell Host & Microbe · 2016 · 133 citations
    4. Hair and nail adverse events during treatment with targeted therapies for metastatic melanoma 2016 · 32 citations
    5. Cutaneous reactions to targeted therapies in children with CNS tumors: A cross‐sectional study Pediatric Blood & Cancer · 2019 · 16 citations
    6. Dyad of infantile cutaneous and thymic Langerhans cell histiocytosis: Is it rare? Pediatric blood & cancer · 2023
    7. 645 MIG6 is MEK-regulated and affects EGF-induced migration in mutant NRAS melanoma Journal of Investigative Dermatology · 2016
    8. 696 MEK and BRAF inhibitors augment the production and accumulation of sebum in hamster sebocytes Journal of Investigative Dermatology · 2016
    9. Multimodal therapeutic approach for a severe case of kaposiform lymphangiomatosis from procedural interventions to targeted therapies Pediatric Blood & Cancer · 2024 · 1 citations
    10. Hydrogel-Forming Microneedles for Transdermal Drug Delivery Preprints.org · 2023 · 10 citations
    11. Biological therapy in the treatment of melanoma Journal of Mind and Medical Sciences · 2018 · 3 citations
    12. The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: the Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma Current Dermatology Reports · 2013 · 6 citations
    13. Cutaneous reactions to chemotherapeutic drugs and targeted therapy for cancer Journal of the American Academy of Dermatology · 2014 · 88 citations
    14. Drug-induced acne Clinics in Dermatology · 2016 · 52 citations
    15. Alopecia in patients treated with molecularly targeted anticancer therapies Annals of Oncology · 2015 · 44 citations
    16. Pathogenesis and treatment options for chemotherapy‐induced alopecia: a systematic review International Journal of Dermatology · 2018 · 34 citations
    17. Clinical management of cutaneous adverse events in patients on targeted anticancer therapies and immunotherapies: a national consensus statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology Clinical & Translational Oncology · 2018 · 26 citations
    18. Alopecia in Association with Malignancy: A Review American Journal of Clinical Dermatology · 2018 · 26 citations
    19. An antimicrobial microneedle patch promotes functional healing of infected wounds through controlled release of adipose tissue-derived apoptotic vesicles Journal of Nanobiotechnology · 2024 · 10 citations
    20. New small molecules in dermatology: for the autoimmunity, inflammation and beyond Inflammation Research · 2023 · 9 citations
    21. Hormone receptor positive, HER2 negative metastatic breast cancer: Impact of CDK4/6 inhibitors on the current treatment paradigm Asia-Pacific Journal of Clinical Oncology · 2018 · 4 citations
    22. Dermatologic adverse events associated with chemotherapy and targeted anticancer therapy Dermatology Review · 2016 · 4 citations
    23. Management of Toxicities of Targeted Therapies Elsevier eBooks · 2018 · 2 citations
    24. Cutaneous Side Effects of Chemotherapy and Radiotherapy 2016 · 2 citations
    25. Adverse Hair Reactions to New Targeted Therapies for Cancer Actas Dermo-Sifiliográficas · 2019 · 1 citations
    26. Graft-versus-host disease with acute hair loss: A distinctive manifestation of chronic graft-versus-host disease Journal of The American Academy of Dermatology · 2016 · 1 citations
    27. Dermoscopy — 4th Conference of the Section of Dermoscopy and Other Skin Imaging Techniques (DiTOS) of the Polish Dermatological Society — Abstracts Forum Dermatologicum · 2026
    28. Hair Changes due to Drugs Elsevier eBooks · 2018
    29. Poster Abstracts Fundamental & Clinical Pharmacology · 2017
    30. 643 Male pattern baldness and risk of incident skin cancer in a cohort of men Journal of Investigative Dermatology · 2016