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This paper presents the first reported case of Acute Localized Exanthematous Pustulosis linked to topical minoxidil use, suggesting a contact-induced hypersensitivity reaction as a potential mechanism.

Raspberry ketone may help grow hair and improve skin elasticity.

This pilot study suggests that using growth factors followed by microneedle therapy may benefit women with female pattern hair loss.

In this study, 1% procyanidin B-2 tonic significantly increased the number of total and terminal hairs on the scalp of male participants compared to a placebo after 6 months of use.

This review reports that cubosomes, used as drug nanocarriers in topical treatments, offer potential benefits for managing skin and eye diseases by improving bioadhesion, retention, and sustained release compared to conventional formulations, but also face manufacturing and biological challenges for effective clinical outcomes.

This study observed that proretinal nanoparticles delivered significantly higher concentrations of retinal to the stratum corneum and hair follicles compared to non-particulate forms, potentially improving topical retinoid therapy.

In this study, topical EGCG significantly reduced testosterone-induced hair loss and follicular apoptosis in mice, without altering testosterone or dihydrotestosterone concentrations.

This study found that daily topical application of citral increased sebaceous gland lobules and cell hyperplasia in male rats after three months.

This review examines the benefits of topical hyaluronic acid in cosmetic applications, noting its ability to penetrate the skin in low-molecular-weight forms and highlighting safety supported by clinical trials.

This study found that PRP was effective for treating alopecia areata with similar improvement across groups, while topical delivery via fractional CO2 laser or microneedling reduced injection pain.

In this study, a chitosan-based minoxidil nanogel was developed and optimized for better scalp retention and targeted follicular delivery, showing sustained drug release over 48 hours and improved drug deposition compared to conventional minoxidil solutions.

This study systematically reviewed the use of topical testosterone products such as creams, gels, and patches, finding they effectively raise serum testosterone but pose significant systemic risks like acne and gynecomastia, necessitating careful medical oversight.

This review highlighted recent advances in nanocarrier-based topical delivery systems for skincare, emphasizing their potential to enhance ingredient stability, penetration, and targeted release while addressing specific pathophysiological skin concerns.

This study developed a nanoemulsion containing Minoxidil, which showed effective stability and significantly increased hair growth rates in pretreated mice, suggesting its potential for treating hair loss.

This study found that the meropenem-loaded spanlastic formulation showed strong potential as an effective topical therapy for bacterial skin infections in non-diabetic mice, demonstrating superior therapeutic activity and wound healing compared to free meropenem.

This study found that coconut oil mixed with egg yolk and vitamin E may enhance hair growth in male rabbits more efficiently than amla, reetha, and sikhakai oil.

This study found that a single topical application of calcipotriol ointment did not affect systemic calcium levels in patients with chronic plaque psoriasis.

This study found no significant difference in the overall effectiveness of fractional CO2 laser plus triamcinolone acetonide versus microneedling plus the same treatment for resistant alopecia areata, though initial hair regrowth appeared more frequently in the laser group.

In this study, extracts of Zataria multiflora Boiss. and Matricaria chamomilla, combined with minoxidil, significantly improved hair growth in androgenetic alopecia patients by potentially inhibiting 5α-reductase activity.

This study developed lipid nanoparticles for delivering minoxidil and finasteride to the dermis and hair follicles, showing stability and a desired prolonged release, though with low skin penetration levels.

This case report describes a potential drug-induced localized scleroderma in a Persian cat following the application of a 'spot-on' treatment.

This review found that topical metformin shows potential as a treatment in dentistry for periodontitis and in dermatology for conditions like wound healing and acne, but results for melasma are inconsistent.

In this study, researchers formulated and evaluated a gel containing minoxidil and aloe vera for alopecia treatment, finding that it was stable and non-irritant on albino rats, suggesting enhanced topical drug delivery over traditional solutions.

This study investigates the potential of a cosmetic day lotion with a 5a-reductase inhibitor and a night lotion with an angiogenic ingredient to modulate hair growth, but reports no clinical results.

This study suggests that novel lipid nanoparticle formulations may be suitable for delivering anti-alopecia compounds like minoxidil and finasteride, although their skin penetration was limited.

This study reviewed preclinical and clinical research and found that AFL-assisted topical drug delivery is considered safe and effective, enhancing drug efficacy, reducing treatment time and pain, and improving cosmetic and safety outcomes, but larger clinical trials are needed to confirm these benefits.

In this study, zinc chloride was found to be severely irritant to the skin in rabbit, guinea-pig, and mouse models, while zinc oxide, zinc sulphate, zinc pyrithione, and zinc undecylenate showed minimal to no irritancy.

This study reported that a 1% procyanidin B-2 tonic increased hair diameter and density in men with male pattern baldness, suggesting it may be a potential treatment option.

This review discusses iontophoresis, low-frequency ultrasound, and microneedles for enhancing topical drug delivery in dermatological treatments and reports no clinical results; it emphasizes their mechanisms and potential uses.