1 citations
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January 2025 in “Journal of Clinical and Investigative Dermatology” This study observed significant improvements in hair loss and hair density among adults using USPlus DERM Topical serum daily for 12 weeks, with 90.9% of participants noticing better hair loss/density and rating satisfaction at an average of 7.7 out of 10.
1 citations
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January 1994 in “Drug Development and Industrial Pharmacy” This study suggests that certain combinations of topical radioprotectors and vehicles can reduce radiation-induced hair loss in mice, with effectiveness varying by radiation dose and vehicle type.
1 citations
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November 1981 in “PubMed” No clear conclusion available.
This study observed that both intradermotherapy with 5% minoxidil and topical minoxidil application resulted in perceived improvements in hair density and thickness among patients with androgenetic alopecia, with no significant difference between the two groups.
April 2026 in “Frontiers in Bioengineering and Biotechnology” This study found that a cellulose membrane significantly shortened the healing time and reduced the ulcer area in patients with chronic venous leg ulcers compared to a standard antimicrobial dressing.
July 2025 in “Current Issues in Molecular Biology” This study evaluated the safety and efficacy of Bio-Pulsed avian mesenchymal stem cell-derived small extracellular vesicles when applied topically, finding significant improvements in hair growth, skin rejuvenation, and regenerative microRNA presence among 60 human participants without adverse events.
This study suggests that topical application of a hydrogel containing magnetized saline water may promote wound healing in stage 2-3 pressure ulcers in elderly patients by stimulating autophagy, based on observed clinical improvements in a case series.
May 2025 in “Indian Journal of Pharmacology” In this study, researchers reported that standardized rosemary and capsicum extracts significantly improved hair growth parameters such as follicle density, length, and diameter in rats with testosterone-induced alopecia, suggesting these extracts may aid in more effective natural treatments for androgenetic alopecia.
April 2024 in “International Journal Of Medical Science And Clinical Invention” This study found that transdermal application of vitamin D cream led to substantial reductions in inflammatory acne among participants with vitamin D deficiency, with all experiencing at least a 30% improvement after one month, and some achieving up to 100% reduction in acne lesions.
January 2024 in “Journal of dermatology and skin science” In this study, researchers found that applying topical aprepitant, which blocks substance P receptors, significantly reduced facial dermatitis and hair loss in rats experiencing erlotinib-induced skin side effects, highlighting the neurogenic inflammation's role and the protective effect of ROS inhibition.
December 2020 in “Jurnal Kedokteran Hewan” In this study, researchers found that cayenne leaf extract significantly enhanced hair length and quantity in mice, with a 10% concentration being the most effective for stimulating growth.
This study found that applying topical cinnamon essential oil on male wistar rats increased hair length and hair follicle diameter similarly to 2% minoxidil over 30 days.
April 2016 in “Journal of Urology and Nephrology Open Access” This abstract discusses treatment options for benign prostatic hyperplasia and provides no new clinical results.
August 2025 in “Biomolecules” This review discusses the potential topical benefits of cannabidiol in dermatology and cosmetics, highlighting its diverse effects and therapeutic roles but reports no new clinical results, emphasizing the need for further research.
11 citations
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July 2020 in “Journal of Cosmetic Dermatology” This study found that a 1% Sandalore® solution reduced hair shedding and improved hair volume and anagen phase duration in women with telogen effluvium over 24 weeks, compared to placebo.
January 2025 in “Pharmaceuticals” This review discusses the role of nanocarrier systems, such as nanoemulsions and liposomes, in delivering antioxidants into the skin to counteract oxidative stress, highlighting recent advancements in topical antioxidant therapy through nanotechnology.
In this study, microneedling radiofrequency followed by topical exosome application was associated with significant increases in hair density and diameter, showing promising potential as a therapy for pattern hair loss.
20 citations
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March 2021 in “Drug design, development and therapy” This review summarizes the pharmacology, mechanisms, and clinical efficacy of topical immunotherapy for alopecia areata but reports no new clinical results.
July 2023 in “GLOBAL JOURNAL FOR RESEARCH ANALYSIS” This study explored a new treatment approach using 20% TCA application with topical bimatoprost solution for managing alopecia areata of the eyebrows in cases where traditional treatments failed, offering a potential additional option for difficult cases.
June 2026 in “YAKUGAKU ZASSHI” This study investigated the impact of container-tip design and hair density on the scalp delivery of minoxidil in topical formulations, finding that higher hair density reduced delivery, particularly with larger tip containers, indicating the importance of these factors in product design.
6 citations
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June 2013 in “Toxicological Research” This study found that topical valproate has minimal potential to cause skin irritation, suggesting it can be applied safely to human skin.
December 2024 in “Egyptian Poultry Science” This study found that topical Ivermectin 0.1% was the most effective treatment for rabbit mange among the tested options, achieving 100% survival, no persistent skin scales, and significant body weight changes, while topical cebacil gel resulted in 100% mortality and should not be used.
August 2020 in “Bioscience Biotechnology Research Communications” This study found that using topical anesthetic was more effective than a vibrating device in reducing discomfort from dental injections.
April 2017 in “Journal of Investigative Dermatology” Applying pseudoceramide improved skin and hair health.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that topical bortezomib increased cell proliferation in hair follicles and sebaceous glands in mice and may activate hair keratin gene expression through GATA-3 transcription factors.
July 2025 in “The Journal of Dermatology” This study reported that 5% topical minoxidil lotion may be beneficial for enhancing hair regrowth in patients with telogen effluvium, although its effectiveness is limited by the self-healing nature of the condition and the small sample size.
December 2025 in “Saudi Journal of Medicine and Public Health” This narrative review highlights the critical role of pharmacists in optimizing topical corticosteroid therapy through proper agent selection, dosing, and patient education to manage various steroid-responsive skin conditions effectively.
63 citations
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April 2018 in “Journal of the American Academy of Dermatology” This review discusses the efficacy and safety of topical JAK inhibitors for inflammatory skin conditions, reporting modest benefits in psoriasis and atopic dermatitis but mixed results for vitiligo and inconclusive data for alopecia areata.
39 citations
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January 2019 in “Journal of Dermatological Treatment” This review found topical ketoconazole to be highly effective against Malassezia-related skin conditions, though other treatments may outperform it for Tinea and Candida infections.
4 citations
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September 2015 in “Case Reports” The authors describe a case of syncope in a young man after using high strength topical minoxidil, which resolved when he stopped the treatment, highlighting a rare documented reaction.