19 citations
,
July 1993 in “Journal of Applied Toxicology” This study found that various petroleum distillates caused significant skin changes in mice, with severity varying based on the product and penetration pathway, potentially leading to skin tumors through non-genotoxic mechanisms in longer-term exposure.
14 citations
,
January 2024 in “Burns & Trauma” In this study on diabetic wound healing in mice, Calvatia gigantea extract accelerated wound recovery, reduced inflammation, and improved the microbiome's diversity, particularly enhancing Escherichia–Shigella bacteria presence.
14 citations
,
July 1977 in “Archives of Dermatology” This case report found that a linoleic acid topical application reversed essential fatty acid deficiency and improved scalp dermatitis, alopecia, and hair depigmentation in a 19-year-old patient on fat-free intravenous nutrition.
8 citations
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September 2017 in “Journal of Natural Medicines” This study reported that the n-butanol fraction of Perilla frutescens extract, particularly rosmarinic acid, showed potential for hair regrowth and anti-androgenic activity in male mice, suggesting it as a possible treatment for androgenetic alopecia.
7 citations
,
July 2022 in “Pharmaceuticals” This study reports that pumpkin seed oil-loaded niosomes significantly decreased hair loss and increased hair growth indicators in vivo, suggesting potential as a natural anti-hair loss therapy.
7 citations
,
April 1996 in “Archives of dermatological research” This study found that after topical application in rats, 1,24-dihydroxyvitamin D3 absorbed through both the stratum corneum and hair follicles, with about 30% excreted via the faeces.
1 citations
,
April 2017 in “Journal of Investigative Dermatology” This study evaluated the effects of topical glucocorticoids on human skin using non-invasive imaging methods and observed changes such as alterations in skin layer thickness, keratinocyte size, and collagen and elastin signal intensity.
1 citations
,
October 2010 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study found that while short-term use of PEG-400 and Thiazone affected rat skin structure, the changes were reversible with no long-term effects observed.
January 2025 in “International Journal of Research and Innovation in Applied Science” This study aimed to enhance the skin penetration of minoxidil by encapsulating it in glycerosomal vesicles, offering a potential improvement in transdermal drug delivery for treating androgenetic alopecia. Results of the investigation were not reported.
January 2012 in “Journal of Investigative Dermatology” July 2021 in “Indian journal of drugs in dermatology” In this study, the combination of intradermal meso-solution and topical 5% minoxidil significantly increased hair re-growth in men with androgenetic alopecia compared to minoxidil alone.
4 citations
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November 2016 in “Dermatologic Therapy” Topical tretinoin may increase beard hair density.
February 2023 in “Sexual Medicine Reviews” This review explores the potential of topical minoxidil as a treatment for erectile dysfunction, indicating that while a mild erectile response was observed, evidence remains insufficient for confirmation.
April 2024 in “Indian journal of ophthalmology. Case reports” This study reports a case of acute central serous chorioretinopathy potentially linked to prolonged topical minoxidil use for alopecia, with improvement following cessation of the treatment.
17 citations
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December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” In this study, once-daily treatment with bimatoprost 0.03% solution significantly increased eyelash growth, thickness, and darkness in patients with chemotherapy-induced eyelash loss compared to placebo, and was well tolerated over one year.
12 citations
,
January 1987 in “Carcinogenesis” This study found that a single application of TCDD on the skin of hairless mice altered epidermal differentiation, changing keratin expression patterns similarly to a known tumor promoter.
2 citations
,
November 2023 in “Bioactive materials” The researchers reported that a newly developed ionic liquid-based microemulsion significantly improved the local delivery of copper peptides in mice, enhancing hair growth-related factor activation while offering a safer, non-invasive alternative to existing treatments for hair loss.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a chitosan-based nanogel for minoxidil, showing in vitro sustained drug release and higher deposition compared to conventional solutions, suggesting potential as an effective topical treatment for alopecia.
September 2022 in “Journal of Cosmetic Dermatology” This article discusses the efficacy of different derma roller sizes compared to topical applications for administering QR678 Neo® in treating androgenetic alopecia, but provides no new clinical results.
21 citations
,
April 2021 in “Biofabrication” This study developed a vascularized full-thickness skin equivalent with a complex vascular network, enhancing its predictiveness for topical and systemic drug applications in dermatology research.
12 citations
,
January 2011 in “Photodermatology, photoimmunology & photomedicine” This study found that phototoxic psoralen and ultraviolet A therapy with topical 8-MOP was effective in treating alopecia areata resistant to other treatments, improving hair regrowth with minimal side effects.
June 2024 in “Journal of Ayub Medical College Abbottabad” This study concluded that adding 5% topical Procapil to PRP therapy provided better outcomes for androgenetic alopecia than PRP alone, as assessed by dermatologist evaluations and patient satisfaction.
115 citations
,
November 1999 in “Journal of The American Academy of Dermatology” In this study, men using 2% and 5% minoxidil solutions experienced a significant increase in hair weight for 96 weeks compared to placebo, with effects diminishing after treatment cessation.
130 citations
,
January 2017 in “International journal of nanomedicine” This study found that Na CMC hydrogel loaded with PEG-coated silver nanoparticles demonstrated superior antibacterial and wound-healing efficacy compared to commercial silver sulfadiazine cream in a wound-healing model.
2 citations
,
March 2015 in “Daehan miyong hakoeji”
2 citations
,
November 2007 in “Journal of Investigative Dermatology” This study found that bulge keratinocytes in mice develop resistance to glucocorticoid treatment more slowly than interfollicular keratinocytes and do not significantly aid in repairing glucocorticoid-induced skin atrophy within five days.
March 2026 in “INDIAN DRUGS” In this study, an antioxidant-rich herbal hair mask with flaxseed and rice water was developed and showed 72% DPPH radical scavenging activity, stable physical parameters, and effective spreadability and foamability, suggesting it may be a cost-effective, environmentally-friendly alternative to artificial hair products.
January 2013 in “CINECA IRIS Institutial research information system (University of Pisa)”
1 citations
,
January 2013 in “International Journal of Medicinal and Aromatic Plants” In a rabbit study, flaxseed oil applied topically significantly increased hair width, while flaxseed ingestion also had a positive effect, but neither method improved hair length or weight.
1 citations
,
October 2020 in “Annales pharmaceutiques françaises” In this study, researchers developed and validated a rapid and robust chromatographic method to assess the concentration of Minoxidil and Finasteride in a new topical formulation for alopecia, demonstrating its ability to distinguish between different types of formulations using in vitro diffusion data.