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    Glossary TNF inhibitors

    medications that block inflammation-causing proteins in autoimmune diseases

    TNF inhibitors, also known as Tumor Necrosis Factor inhibitors or TNF blockers, are medications that reduce inflammation by blocking the activity of TNF-alpha, a substance in the body that causes inflammation and can lead to immune system diseases. They are commonly used to treat autoimmune conditions such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease by preventing the immune system from attacking healthy tissues.

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    1. TNF inhibitor induced alopecia: an unusual form of psoriasiform alopecia that breaks the Renbök mold Dermatology Online Journal · 2017 · 9 citations
    2. TNF-α Inhibitor-Induced Psoriasis and Psoriatic Alopecia in Adolescent with Ulcerative Colitis: Clinical Case Вопросы современной педиатрии · 2023 · 3 citations
    3. Oral contraceptive pill (OCP) treatment alters the gene expression of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein-1 (MCP-1) and plasminogen activator inhibitor-1 (PAI-1) in polycystic ovary syndrome (PCOS) women compared to drug-naive PCOS women BMC women's health · 2023 · 2 citations
    4. Immune-Mediated Skin Reactions Induced by Recombinant Antibodies and Other TNF-Alpha Inhibitors InTech eBooks · 2018 · 2 citations
    5. The development of universal alopecia during therapy with TNF-α inhibitors in patients with ankylosing spondylitis: description of three cases Rheumatology Science and Practice · 2021
    6. TNF‐inhibitor associated psoriatic alopecia: Diagnostic utility of sebaceous lobule atrophy Journal of cutaneous pathology · 2017 · 20 citations
    7. Lessons from TNF-α Inhibitor–Induced Alopecia Areata: Does TNF-α Operate as a Hair Follicle Immune Privilege Guardian under Inflammatory Conditions? Journal of Investigative Dermatology · 2025 · 2 citations
    8. 0248 Risk of infections in patients with hidradenitis suppurativa treated with TNF-α inhibitors vs. IL-17 inhibitors: A large-scale cohort study Journal of Investigative Dermatology · 2025
    9. 64750 Which lessons on the role of TNF-a in hair follicle (patho-)biology can be learned from TNF-a inhibitor-induced alopecia areata? Journal of the American Academy of Dermatology · 2025
    10. Increased Macrophage Migration Inhibitory Factor (MIF) in the Sera of Patients with Extensive Alopecia Areata 2002 · 14 citations
    11. Trichorrhexis nodosa: a distinctive presentation after tumour necrosis factor-α inhibitor therapy Clinical and Experimental Dermatology · 2015 · 10 citations
    12. Off-label use of biologics and janus kinase (JAK) inhibitors for scarring alopecias: a narrative review Archives of Dermatological Research · 2025 · 3 citations
    13. Tumor necrosis factor α inhibitor-induced alopecia in pediatric patients: a cohort of 20 patients and review of the literature Archives of Dermatological Research · 2025 · 3 citations
    14. Hair Loss Induced by Tumor Necrosis Factor Alpha Inhibitors Journal of clinical and investigative dermatology · 2014 · 2 citations
    15. Progressive alopecia areata during TNF-α inhibition with intralesional corticosteroid failure and subsequent improvement following JAK1 inhibition Journal of Dermatological Treatment · 2026 · 1 citations
    16. P07 Pityriasis amiantacea: a unique presentation of psoriasis associated with tumour necrosis factor-α inhibitor therapy Rheumatology advances in practice · 2023 · 1 citations
    17. Tumor necrosis factor-alpha inhibitor associated psoriasiform alopecia (drug-induced psoriasiform alopecia) Informa Healthcare eBooks · 2012 · 1 citations
    18. Psoriatic Alopecia in a Patient With Crohn Disease: An Uncommon Manifestation of Tumor Necrosis Factor α Inhibitors Cutis · 2021
    19. - Tumor necrosis factor-alpha inhibitor associated psoriasiform alopecia (drug-induced psoriasiform alopecia) CRC Press eBooks · 2012
    20. Tumor necrosis factor-alpha inhibitor associated psoriasiform alopecia (drug-induced psoriasiform alopecia) Informa Healthcare eBooks · 2012
    21. Biologic Therapies and Small-Molecule Inhibitors for Dissecting Cellulitis of the Scalp: A Systematic Review Dermatology and Therapy · 2026
    22. A systematic review of tumor necrosis factor-α blockers, anti-interleukins, and small molecule inhibitors for dissecting cellulitis of the scalp treatment Orphanet Journal of Rare Diseases · 2025
    23. Tumor necrosis factor inhibitors and janus kinase inhibitors in the treatment of cicatricial alopecia: A systematic review PloS one · 2024
    24. TNF-a in nonscarring inflammatory alopecia Journal of The American Academy of Dermatology · 2014
    25. Treatment of Cultured Sebocytes with an EGFR Inhibitor Does Not Lead to Significant Upregulation of Inflammatory Biomarkers Annals of Dermatology · 2011 · 3 citations
    26. Perifolliculitis capitis abscedens et suffodiens treatment with tumor necrosis factor inhibitors and baricitinib: A case report and literature review Frontiers in medicine · 2023 · 2 citations
    27. Review article: dermatological complications of immunosuppressive and anti-TNF therapy in inflammatory bowel disease Alimentary Pharmacology & Therapeutics · 2013 · 60 citations
    28. Advanced glycation end-products inhibit mesenchymal-epidermal interaction by up-regulating proinflammatory cytokines in hair follicles European Journal of Dermatology · 2015 · 3 citations
    29. Total glucosides of paeony inhibit NLRP3/caspase-1/GSDMD-mediated inflammation and pyroptosis in C3H/HeJ mice with alopecia areata Biomolecules and Biomedicine · 2024 · 5 citations
    30. Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition Psychoneuroendocrinology · 2018 · 37 citations