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    Glossary Transglutaminase 3

    enzyme crucial for skin and hair protein cross-linking

    Transglutaminase 3 (TGM3) is an enzyme that plays a crucial role in the formation and maintenance of the outer layer of the skin and hair follicles. It helps in the cross-linking of proteins, which strengthens the structural integrity of these tissues. Deficiencies or malfunctions in TGM3 can lead to skin disorders and hair loss conditions.

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    1. Targeted Inactivation of Gh/Tissue Transglutaminase II Journal of Biological Chemistry · 2001 · 288 citations
    2. Immunohistochemical analysis of tissue remodelling during the anagen-catagen transition of the human hair follicle British Journal of Dermatology · 1997 · 47 citations
    3. Petechiae on the fingertips as presenting symptom of dermatitis herpetiformis Duhring Journal of the European Academy of Dermatology and Venereology · 2009 · 30 citations
    4. 1329 Transglutaminase 2 deficiency leads to lipid accumulation and reduced autophagy in SZ95 sebocytes 2023
    5. Clinical case of delayed diagnosis of celiac enteropathy Sučasna gastroenterologìâ · 2024
    6. Hair loss in women 2016
    7. Transglutaminase-3, an esophageal cancer-related gene International Journal of Cancer · 2000 · 32 citations
    8. Transglutaminase Activity Is Conserved in Stratified Epithelia and Skin Appendages of Mammals and Birds International journal of molecular sciences · 2023 · 8 citations
    9. Epithelial barrier function: assembly and structural features of the cornified cell envelope BioEssays · 2002 · 425 citations
    10. Ultrastructural visualization of cross-linked protein features in epidermal appendages Journal of Cell Science · 1994 · 43 citations
    11. 322 Upregulation of SERPINB3/B4 and S100A7-9 in hidradenitis suppurativa/acne inversa 2019
    12. A trichobezoar in a child with undiagnosed celiac disease: A case report World journal of gastroenterology · 2014 · 9 citations
    13. Co-existence of Systemic Lupus Erythematosus and Celiac Disease: A Case Report Pakistan Journal of Medicine and Dentistry · 2024
    14. Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications Chemical Society Reviews · 2015 · 421 citations
    15. Stem Cell-Based Tissue Engineering for the Treatment of Burn Wounds: A Systematic Review of Preclinical Studies Stem Cell Reviews and Reports · 2022 · 30 citations
    16. Hair Follicle Transglutaminases and the Formation of ε-(γ-Glutamyl) Cross-links 1981
    17. Identification of a preferred substrate peptide for transglutaminase 3 and detection of <i>in situ</i> activity in skin and hair follicles ˜The œFEBS journal · 2010 · 35 citations
    18. Apoptosis in human skin development: Morphogenesis, periderm, and stem cells Developmental dynamics · 1994 · 253 citations
    19. Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding? 2008 · 30 citations
    20. Transglutaminase 3: The Involvement in Epithelial Differentiation and Cancer Cells · 2020 · 22 citations
    21. Tissue engineering of skin and regenerative medicine for wound care Burns & Trauma · 2018 · 192 citations
    22. Beyond Expectations International review of cell and molecular biology · 2014 · 70 citations
    23. Fatty acids and related lipid mediators in the regulation of cutaneous inflammation Biochemical Society Transactions · 2018 · 28 citations
    24. Advanced therapies of skin injuries Wiener Klinische Wochenschrift · 2015 · 28 citations
    25. A preliminary study of differentially expressed genes in expanded skin and normal skin: implications for adult skin regeneration Archives of Dermatological Research · 2011 · 16 citations
    26. Hydrogels Modulating the Microbiome: Therapies for Tissue Regeneration with Infection Control Gels · 2025 · 8 citations
    27. Transglutaminase 5 Expression in Human Hair Follicle Journal of Investigative Dermatology · 2005 · 28 citations
    28. Recent advances in understanding of radiation-induced skin tissue reactions with respect to acute tissue injury and late adverse effect Journal of Radiation Research · 2025 · 5 citations
    29. A regenerative stem cell-derived matrix accelerates functional dermal wound repair in a preclinical diabetic model 2026
    30. Injectable Biomaterials for Dental Tissue Regeneration International Journal of Molecular Sciences · 2020 · 82 citations