40 citations,
November 2011 in “American Journal of Human Biology” Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.
40 citations,
April 2008 in “European journal of endocrinology” Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.
39 citations,
January 2012 in “Reproductive Biology and Endocrinology” About 8.5% of women in Salvador, Brazil, have Polycystic Ovary Syndrome.
39 citations,
November 1978 in “Annals of internal medicine” Spironolactone may help reduce excessive hair growth in women with high male hormone levels.
39 citations,
September 2000 in “Obstetrics and Gynecology Clinics of North America” Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.
38 citations,
October 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity” 5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.
38 citations,
January 1997 in “Gynecological Endocrinology” Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.
37 citations,
May 2018 in “Transgender health” Oral estradiol works for many transgender women but needs personalized dosing and monitoring.
37 citations,
April 2013 in “Plastic and Reconstructive Surgery” Genetic and environmental factors, like smoking and exercise, affect male hair loss.
36 citations,
May 2017 in “The journal of sexual medicine” Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.