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    Glossary Testosterone Production

    process by which the body generates the hormone testosterone

    Testosterone production, also known as testosterone synthesis or androgen production, refers to the process by which the body generates testosterone, a key male sex hormone. This process primarily occurs in the testes in men and in smaller amounts in the ovaries in women and the adrenal glands in both sexes. Testosterone plays a crucial role in the development of male reproductive tissues, the maintenance of muscle mass, bone density, and the regulation of libido. The production is regulated by the hypothalamus and pituitary gland through a feedback loop involving luteinizing hormone (LH).

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    1. Re: Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men with Suppressed Testosterone Production: A Randomized Controlled Trial The Journal of Urology · 2012
    2. Production rates of testosterone and of dihydrotestosterone in female pattern hair loss Metabolism-clinical and Experimental · 2003 · 17 citations
    3. Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone American Journal of Physiology-Endocrinology and Metabolism · 2014 · 53 citations
    4. Testosterone and dihydrotestosterone production in genetically furless and furred male rabbits and effects on growth. Proceedings of the 9th World Rabbit Congress, Verona, Italy, 10-13 June 2008 · 2008 · 1 citations
    5. Obstructive Sleep Apnea Due to Endogenous Testosterone Production in a Woman Mayo Clinic Proceedings · 1998 · 66 citations
    6. Testosterone stimulates proliferation and inhibits interleukin‐6 production of normal and hereditary gingival fibromatosis fibroblasts Oral Microbiology and Immunology · 2002 · 39 citations
    7. CHRONIC TREATMENT REGIMENS FOR HIRSUTISM IN WOMEN: EFFECT ON BLOOD PRODUCTION RATES OF TESTOSTERONE AND ON HAIR GROWTH Clinical Endocrinology · 1975 · 29 citations
    8. Prostaglandin D2 Uses Components of ROS Signaling to Enhance Testosterone Production in Keratinocytes Journal of Investigative Dermatology Symposium Proceedings · 2017 · 9 citations
    9. Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men With Suppressed Testosterone Production JAMA · 2012 · 124 citations
    10. A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice British Journal of Dermatology · 1997 · 10 citations
    11. A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice British Journal of Dermatology · 1997 · 9 citations
    12. Potential adverse effects of long-term testosterone therapy Baillière's clinical endocrinology and metabolism · 1998 · 72 citations
    13. Testosterone Is a Contraceptive and Should Not Be Used in Men Who Desire Fertility The World Journal of Men's Health · 2019 · 39 citations
    14. New Insights into Testosterone Biosynthesis: Novel Observations from HSD17B3 Deficient Mice International journal of molecular sciences · 2022 · 8 citations
    15. Impact of Testosterone on Hair and Skin Endocrinology & metabolic syndrome · 2015 · 4 citations
    16. Inhibition of Rat 5<i>α</i>-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of<i>Quercus acutissima</i>Cortex Evidence-based Complementary and Alternative Medicine · 2015 · 37 citations
    17. AN ATTEMPT TO ASSESS THE MAGNITUDE OF ENDOGENOUS ANDROGEN PRODUCTION IN A CASE OF THE ADRENOGENITAL SYNDROME* The Journal of Clinical Endocrinology & Metabolism · 1952 · 9 citations
    18. Testosterone Hormone ; Clinical Indications, Dysregulation and Therapeutic methods ˜Al-œAmeed journal for medical research and health sciences · 2024
    19. Association between exogenous testosterone use and new diagnosis of hidradenitis suppurativa: A case series JAAD case reports · 2023
    20. Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin Springer eBooks · 2014
    21. The influence of non-esterified fatty acids (NEFA) on the ovarian production of androgens in a context of in vitro fertilisation (IVF) – preliminary results Fertility and Sterility · 2013
    22. [Clinical significance of testosterone and dihydrotestosterone metabolism in women]. PubMed · 1996
    23. Effects of Sex Steroid Deprivation/Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females 2000 · 176 citations
    24. Children’s hair cortisol and hair testosterone concentrations in response to environmental changes: from summer holidays to school Stress · 2021 · 3 citations
    25. 46,XY DSD due to impaired androgen production 2010 · 54 citations
    26. Anabolic and Metabolic Effects of Testosterone and Other Androgens: Direct Effects and Role of Testosterone Metabolic Products Endocrinology · 2017 · 2 citations
    27. Gonadal Sex Steroids: Production, Action and Interactions in Mammals InTech eBooks · 2012 · 2 citations
    28. 854 Dermal fibroblasts enhance growth factors production by androgens, and modulate keratinocyte proliferation and differentiation 2018
    29. High-throughput and direct measurement of androgen levels using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS) to discover chemicals that modulate dihydrotestosterone production in human prostate cancer cells Biotechnology Letters · 2017 · 2 citations
    30. Dual Wavelength LEDs Induce Reactive Oxygen Species and Nitric Oxide That Inhibit the Production of Dihydrotestosterone by 5‐α Reductase Journal of Biophotonics · 2024