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    Did you mean Terminal Differentiation?
    Glossary Terminal Differentiation

    cell's final development into a specialized, non-dividing state

    Terminal differentiation is the process by which a cell undergoes its final stage of development, becoming a specialized cell type with a specific function, such as a skin cell or a neuron. Once a cell has terminally differentiated, it typically loses the ability to divide and produce new cells, focusing instead on performing its specialized role. This process is crucial for the proper functioning of tissues and organs in the body.

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    1. The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target during Hair Follicle and Nail Differentiation 2010 · 68 citations
    2. Involucrin: A Constituent of Cross-Linked Envelopes and Marker of Squamous Maturation 1986 · 23 citations
    3. Localization of Plasminogen Activator Inhibitor Type 2 (PAI-2) in Hair and Nail: Implications for Terminal Differentiation 1998 · 42 citations
    4. Association of basonuclin with ability of keratinocytes to multiply and with absence of terminal differentiation. The Journal of Cell Biology · 1994 · 104 citations
    5. Regulation of epidermal proliferation and hair follicle cycling by synthetic photostable retinoid EC23 Journal of cosmetic dermatology · 2023
    6. Apoptosis in human skin development: Morphogenesis, periderm, and stem cells Developmental dynamics · 1994 · 253 citations
    7. Selective Expression of Calcium-Binding Proteins S100A8 and S100A9 at Distinct Sites of Hair Follicles Journal of Investigative Dermatology · 2001 · 22 citations
    8. Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix European Journal of Cell Biology · 2017 · 30 citations
    9. Neutrophil gelatinase‐associated lipocalin is a marker for dysregulated keratinocyte differentiation in human skin Experimental dermatology · 2002 · 96 citations
    10. The cDNA-deduced amino acid sequence for trichohyalin, a differentiation marker in the hair follicle, contains a 23 amino acid repeat. 1990 · 39 citations
    11. Two Mechanisms Regulate Keratin K15 Expression In Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signalling PloS one · 2012 · 35 citations
    12. Transient expression of keratin 19 is induced in originally negative interfollicular epidermal cells by adhesion of suspended cells. PubMed · 2005 · 25 citations
    13. Epidermal keratinocyte stem cells: their maintenance and regulation Seminars in cell biology · 1992 · 25 citations
    14. A practical guide for the study of human and murine sebaceous glands <i>in situ</i> Experimental Dermatology · 2013 · 56 citations
    15. Androgen Regulation of the Human Hair Follicle: The Type I Hair Keratin hHa7 Is a Direct Target Gene in Trichocytes Journal of Investigative Dermatology · 2004 · 49 citations
    16. Overexpression of the calcium sensing receptor accelerates epidermal differentiation and permeability barrier formation in vivo Mechanisms of Development · 2003 · 46 citations
    17. Nuclear Factor I-C promotes proliferation and differentiation of apical papilla-derived human stem cells in vitro Experimental Cell Research · 2015 · 24 citations
    18. The role of cathepsin E in terminal differentiation of keratinocytes Biological Chemistry · 2011 · 15 citations
    19. NFIC promotes the vitality and osteogenic differentiation of rat dental follicle cells Journal of Molecular Histology · 2019 · 11 citations
    20. Autophagy-Mediated Cellular Remodeling during Terminal Differentiation of Keratinocytes in the Epidermis and Skin Appendages Cells · 2024 · 7 citations
    21. Androgens induce sebaceous differentiation in sebocyte cells expressing a stable functional androgen receptor 2015 · 31 citations
    22. Characterization of Mouse Profilaggrin: Evidence for Nuclear Engulfment and Translocation of the Profilaggrin B-Domain during Epidermal Differentiation 2002 · 25 citations
    23. Epithelial Skin Biology Current Topics in Developmental Biology · 2016 · 118 citations
    24. Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold Biomolecules · 2020 · 29 citations
    25. Biochemistry of epidermal stem cells Biochimica et Biophysica Acta (BBA) - General Subjects · 2012 · 26 citations
    26. Are hair follicle stem cells promising candidates for wound healing? Expert Opinion on Biological Therapy · 2018 · 18 citations
    27. Laminin 332 Is Indispensable for Homeostatic Epidermal Differentiation Programs 2021 · 12 citations
    28. LB1077 Cutaneous responses to systemic iron: A potential role for epidermal turnover in mammalian iron excretion Journal of Investigative Dermatology · 2019
    29. LB1081 Three-dimensional imaging of tight junction-network across multiple layers of human epidermis by array tomography using backscattered electron-mode scanning electron microscopy Journal of Investigative Dermatology · 2019
    30. Author response: A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea 2019