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    Did you mean T cell infiltration?
    Glossary T cell infiltration

    movement of T lymphocytes into tissue, often causing inflammation

    T cell infiltration refers to the movement and accumulation of T lymphocytes (a type of white blood cell) into a specific tissue or organ. This process often occurs in response to infection, inflammation, or autoimmune conditions, where T cells target and attack perceived threats, such as pathogens or, in some cases, the body's own cells. In the context of alopecia, T cell infiltration can lead to the immune system attacking hair follicles, resulting in hair loss.

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    1. ISID1373 - Expression of programmed cell death 1 inversely correlated with the density of CD8+ T cells infiltrating hair follicles in alopecia areata 2023
    2. 1373 Expression of programmed cell death 1 inversely correlated with the density of CD8+ T cells infiltrating hair follicles in alopecia areata Journal of Investigative Dermatology · 2023
    3. Dandruff lesional scalp skin exhibits epidermal T cell infiltration and a weakened hair follicle immune privilege International Journal of Cosmetic Science · 2024
    4. Alopecia areata but not androgenetic alopecia is characterized by a restricted and oligoclonal T-cell receptor-repertoire among infiltrating lymphocytes Journal of Cutaneous Pathology · 1997 · 19 citations
    5. CD80CD86 deficiency disrupts regulatory CD4+FoxP3+T cell homoeostasis and induces autoimmune-like alopecia Experimental dermatology · 2017 · 6 citations
    6. Immunohistochemical analysis of T-cell subsets in the inflammatory infiltrates of alopecia areata and its comparison with androgenetic alopecia International Journal of Dermatology · 2020
    7. Direct T-cell effects of minoxidii Clinics in Dermatology · 1988 · 7 citations
    8. A biopsy-sized 3D skin model with a perifollicular vascular plexus enables studying immune cell trafficking in the skin Biofabrication · 2024 · 6 citations
    9. 0150 Single-cell and spatial transcriptome profiling reveals innate-adaptive crosstalk in alopecia areata Journal of Investigative Dermatology · 2025
    10. TNC+ fibroblasts involve in skin inflammation via neuro-immune and interacting with T cells Research Square (Research Square) · 2023
    11. 452 Braicitinib treatment reduced the expansion of CD8+ T cells in C3H mice with skin grafts-induced alopecia areata Regular and Young Investigator Award Abstracts · 2023
    12. Spatial transcriptome reveals disturbance of peri-infundibular immune infiltration in androgenetic alopecia Research Square (Research Square) · 2023
    13. Skin-infiltrating CD4+ lymphoma cells depend on hair follicle-derived IL-7 Journal of Dermatological Science · 2016
    14. Investigation of hub genes and immune infiltration in androgenetic alopecia using bioinformatics analysis Annals of Translational Medicine · 2022
    15. 001 Human scalp hair follicles are protected from alopecia areata in vivo by regulatory γδT cells Journal of Investigative Dermatology · 2024
    16. A mouse model of vitiligo based on endogenous auto-reactive CD8 + T cell targeting skin melanocyte Cell Regeneration · 2022 · 24 citations
    17. PD23-01 INHIBITOR OF 5A-REDUCTASE TYPES II PROMOTES THE INFILTRATION OF CD8+T CELLS IN BPH TISSUES. The Journal of Urology · 2014
    18. An unusual variant of granulomatous adnexotropic cutaneous T-cell lymphoma British Journal of Dermatology · 2003 · 23 citations
    19. Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis 2013 · 51 citations
    20. An overview of JAK/STAT pathways and JAK inhibition in alopecia areata Frontiers in immunology · 2022 · 40 citations
    21. ALOPECIA UNIVERSALIS TREATED WITH ORAL CYCLOSPORINE A AND PREDNISOLONE: IMMUNOLOGIC STUDIES International Journal of Dermatology · 1992 · 26 citations
    22. Early stage alopecia areata is associated with inflammation in the upper dermis and damage to the hair follicle infundibulum Australasian Journal of Dermatology · 2013 · 22 citations
    23. Alopecia areata multiplex following autologous dermal micrograft injection for treatment of androgenetic alopecia Journal of The European Academy of Dermatology and Venereology · 2019 · 4 citations
    24. Alopecia Areata Springer eBooks · 2017 · 1 citations
    25. Ruxolitinib reverses alopecia areata via a triple mechanism: JAK-STAT inhibition, localized oxidative stress attenuation and selective apoptosis modulation Journal of Translational Autoimmunity · 2026
    26. ROS-responsive hydrogel-delivered miR-665 targets STAT3 to alleviate inflammation and promote hair follicle regeneration in alopecia areata Figshare · 2026
    27. ROS-responsive hydrogel-delivered miR-665 targets STAT3 to alleviate inflammation and promote hair follicle regeneration in alopecia areata Figshare · 2026
    28. Intranasal sensitization model of alopecia areata using pertussis toxin as adjuvant Frontiers in Immunology · 2024
    29. 766 H3K9me3 methyltransferase SETDB1 controls retrotransposon silencing, DNA methylation, constitutive heterochromatin maintenance and 3D-chromatin structure in epidermal keratinocytes 2023
    30. IL-33 Contributes to the Pathological Changes of Hair Follicles in Psoriasis: A Potential Target for Psoriatic Alopecia Clinical, cosmetic and investigational dermatology · 2023