research Immune Cell Regulation of the Hair Cycle
Immune cells affect hair growth and could lead to new hair loss treatments.
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research Evaluation of Androgens in the Scalp Hair and Plasma of Patients with Male-Pattern Baldness Before and After Finasteride Administration
Finasteride lowers scalp and blood DHT levels, potentially treating male-pattern baldness.
research Mechanism of Action of Androgen in Hair Follicles
Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.
research Cytokine Targeted Therapeutics for Alopecia Areata: Lessons from Atopic Dermatitis and Other Inflammatory Skin Diseases
Targeted cytokine treatments may help with alopecia areata, but more research is needed.
research Treatment of Alopecia Areata: What Is New on the Horizon?
New treatments for alopecia areata may target specific immune cells and pathways involved in hair loss.
research The Role of Natural Killer Cells in Autoimmune Blistering Diseases
Natural killer cells play a key role in autoimmune skin diseases like pemphigus vulgaris.
research Human Androgenic Steroids Affect Growth of Dermatophytes In Vitro
Androgenic steroids can slow down or stop the growth of certain skin fungi.
research Steroidomics for Highlighting Novel Serum Biomarkers of Testosterone Doping
Monitoring steroid hormones in blood can better detect testosterone doping.
research Sebaceous Gland, Hair Shaft, and Epidermal Barrier Abnormalities in Keratosis Pilaris with and without Filaggrin Deficiency
Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.
research Alopecia: A Pathologist's View
The review concludes that accurate diagnosis of different types of hair loss requires proper biopsy techniques and understanding the hair growth cycle and underlying causes.
research Circulating Androgen Levels Before and After Oophorectomy in Premenopausal and Postmenopausal Women
Oophorectomy lowers testosterone and estrogen levels in both premenopausal and postmenopausal women, with postmenopausal women still producing significant testosterone.
research Human Clinical Phenotype Associated With FOXN1 Mutations
FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.
research Relapse of Hirsutism Following Long-Term Successful Treatment with Estrogen-Progestogen Combination
Most patients experienced hirsutism again after stopping hormone treatment, indicating long-term treatment is needed to maintain results.
research Treatment of Alopecia Areata with Simvastatin and Ezetimibe
Simvastatin/ezetimibe may help treat new cases of alopecia areata but not long-term cases.
research Treatment of Hirsutism with Flutamide and a Low-Dosage Oral Contraceptive in Polycystic Ovarian Disease Patients
Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.
research Modeling Cell-Cell Communication for Immune Systems Across Space and Time
The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
research Occipital Involvement in Female Pattern Hair Loss: Histopathological Evidence
Occipital scalp affects female hair loss; terminal/vellus ratio helps diagnose androgenetic alopecia.
research Hyperandrogenemia in Women with Polycystic Ovary Syndrome: Prevalence, Characteristics, and Association with Body Mass Index
High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.
research Synthesis and Pharmacological Evaluation of New 16-Methyl Pregnane Derivatives
New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
research Improved Fetal Hair Follicle Development by Maternal Supplement of Selenium at Nano Size (Nano-Se)
Maternal Nano-Se supplements improve fetal hair follicle development in cashmere goats.
research Clinical Characterization of Men with Long QT Syndrome and Torsades de Pointes Associated with Hypogonadism: A Review and Pharmacovigilance Study
Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.
research Nail Involvement in Frontal Fibrosing Alopecia
Frontal fibrosing alopecia may affect nails and could be a type of lichen planus, treatable with certain medications.
research Establishment of Keratinocyte Cell Lines from Human Hair Follicles
Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
research A Comparative Analysis of Immune Privilege in Pregnancy and Cancer in the Context of Checkpoint Blockade Immunotherapy
The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.
research Alopecia Universalis During Treatment with Leflunomide and Adalimumab: Case Report
A patient lost all their hair while on rheumatoid arthritis medication.
research Topical Nitrogen Mustard in the Treatment of Alopecia Areata: A Bilateral Comparison Study
Nitrogen mustard was not very effective for hair regrowth in alopecia areata and has potential skin cancer risk.
research The Promise and Challenges of Cell Therapy for Psoriasis
Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
research A Hair-Raising History of Alopecia Areata
The document concludes that understanding and treatments for alopecia areata have significantly advanced, now recognizing it as an autoimmune disorder.
research Cutaneous Manifestations Associated With Immune Checkpoint Inhibitors
Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.
research Vitamin D and Alopecia Areata: Possible Roles in Pathogenesis and Potential Implications for Therapy
Vitamin D might be involved in the development of alopecia areata and could help in its treatment.