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The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Muscles can make their own androgens, which may help muscle growth.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.

Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.

The study developed a method to detect minoxidil and its sulfate form, found that minoxidil sulfate is temperature-sensitive, and identified a way to potentially increase its stability for hair loss treatment.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Rosuvastatin improves lipid levels, reduces inflammation, but worsens insulin sensitivity in men with early-onset hair loss.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Stem cell niches support, regulate, and coordinate stem cell functions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

DHT, a testosterone byproduct, causes male pattern baldness.

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.