September 1997 in “Journal of The European Academy of Dermatology and Venereology” Hormonal differences affect male pattern baldness.
5 citations
,
January 2018 in “International Journal of Trichology” This study found no significant difference in the tensile properties of hair from different scalp positions, suggesting that microscopic structural heterogeneities may play a role.
1 citations
,
September 2012 in “Revista Latinoamericana de Psicopatologia Fundamental” In this study, researchers concluded that sexual identity does not determine the choice of sex object, partner genders, or sexual practices among individuals born with sex differentiation disorders.
28 citations
,
July 2000 in “PubMed” This study found no structural differences between in vitro and in vivo grown hair, with keratinization and organization of keratin being comparable in both settings.
1 citations
,
March 2014 in “Journal of Innovative Optical Health Sciences” This study found that in mice, wool structure deteriorates as a malignant tumor develops, suggesting potential uses in cancer diagnostics.
March 2008 in “The Knowledge Bank (The Ohio State University)” This study found that AR-007 degrades faster and has a stronger association with hsp70 than AR-014, suggesting it is less stable when bound to the androgen receptor.
34 citations
,
March 2009 in “Journal of Investigative Dermatology” Proteomic analysis can identify genetic differences in mouse hair, helping understand hair defects and variations.
1 citations
,
January 2021 in “Pakistan journal of zoology” This study identified significant differences in medullary structure, hair length, and root diameter among dorsal guard hairs of red foxes, golden jackals, and gray wolves in Turkey.
48 citations
,
April 2010 in “Journal of the European Academy of Dermatology and Venereology” This article reviews gender differences in skin disorders, highlighting variations in disease prevalence and type between sexes, but reports no new findings, emphasizing potential implications for prevention and treatment strategies.
January 2006 in “Seibutsu Butsuri” Curly and straight hair differ in how their internal fibers are arranged.
82 citations
,
January 2006 in “International review of cytology” Vertebrate skin evolved to be more specialized and complex, especially in land animals.
8 citations
,
June 2022 in “Scientific Reports” Using a transgenic pig model, this study demonstrated that LGR5 is a marker of hair follicle stem cells across different species, with important similarities and differences in gene expression and developmental processes.
2 citations
,
March 2005 in “International Journal of Cosmetic Science” Human hair structure varies by ethnicity, and certain treatments can improve hair condition and appearance.
193 citations
,
August 1985 in “Endocrinology” This study found significant species differences in the enzyme activity and inhibitor affinities of prostatic 5α-reductases from rats, dogs, and humans, with variable potencies for different 3-oxo-4-azasteroid inhibitors across species.
51 citations
,
October 2024 in “Pharmaceutics” This review highlights the potential of permeation enhancers to improve the delivery of active ingredients across the skin, optimizing therapeutic outcomes despite challenges posed by individual variability and environmental factors, according to the authors' analysis of current understanding and applications in skincare and transdermal therapies.
30 citations
,
July 2000 in “PubMed” This study used advanced analytical techniques to reveal that proteins and lipids are distributed unevenly in hair, with distinct structural differences depending on their location within the fiber.
7 citations
,
February 2014 in “Talanta” This study developed an advanced HPLC-ESI-ion trap MS(n) method for the structural identification of cyclosporin A analogs CyA and CyC and reported the first MS(n)-aided identification of a new CyA analog.
August 2024 in “Biophysics Reviews” This study explores the physical properties of hair from various wild mammalian species using polarized light microscopy, aiming to correlate these properties with the internal structures such as the medulla, cortex, and keratin cuticle.
107 citations
,
October 2014 in “PeerJ” This study found that while molecular hair structures were nearly identical across individuals, genetic factors seem to influence specific lipid compositions, as seen in identical-patterned hair from parent-child pairs and identical twins, but not fraternal twins.
76 citations
,
September 1992 in “Endocrinology” This study details the isolation and characterization of the human type II 5 alpha-reductase gene, which may play a role in male pseudohermaphroditism, prostate cancer, and benign prostatic hyperplasia.
40 citations
,
September 2004 in “Biomacromolecules” In this study, molecular dynamics simulations indicated that the Glu413Lys mutation in human hair keratin significantly affects the stability of coiled coil structures, whereas Glu413Asp showed no impact on stability.
10 citations
,
January 2012 in “Journal of biomedical optics” This study used ultrahigh-resolution optical coherence tomography to observe hair shaft structures, finding melanin granules absent only in white hair, which may explain color differences between black and white hair.
4 citations
,
November 2024 in “Materials” In this study, researchers created nanowhiskers from crab shell-derived nanochitin that self-assembled into vibrant structural colors within a film. The material, sensitive to environmental changes, shows potential as a food freshness indicator and a sustainable dye for cosmetics due to chitin's biocompatibility.
9 citations
,
May 2022 in “Actas Dermo-Sifiliográficas” This study found that basal cell carcinoma exhibits altered expression patterns of CD10, p63, BCL-2, and EMA proteins compared to normal skin, with notable differences in staining and reactivity.
13 citations
,
November 2012 in “International Journal of Dermatology” This study of African-American women found that those perceiving greater hair breakage showed lower break stress and higher premature failure rates, linked to grooming practices and hair curvature.
December 2025 in “Frontiers in Veterinary Science” This study found that PT-LCG extends hair follicle activity and promotes continuous cashmere growth by enhancing lipid synthesis, remodeling the extracellular matrix, and modulating inflammatory signaling, offering insights into improving cashmere yield and quality through molecular breeding.
25 citations
,
May 2019 in “Heliyon” This study found that excessive heat caused the most significant structural changes in hair from Caucasian and Afro samples, especially when combined with other treatments like bleaching and straightening.
7 citations
,
September 2020 in “Bioscience Biotechnology and Biochemistry” This study found that bacterial community structures on hair and scalp differ significantly, with distinct abundances of Pseudomonas on hair and Staphylococcus on scalp.
June 2025 in “Reports of Morphology” This study in young Ukrainian men found that specific body measurements, like shoulder width and tibia epiphysis width, are highly predictive of alopecia areata occurrence, though not for its progression, using discriminant models (p<0.001).
January 2021 in “Dermatology Research and Practice” This study will explore skin and hair characteristics of pregnant women and their newborns, examining the relationships between these factors and the newborns' skin maturation over time.