January 2017 in “Durham e-Theses (Durham University)” This study developed new label-free imaging methods to analyze human hair, identifying distinct chemical environments within cuticle layers and changes in hair structure caused by depilatories, while showing that the treatments tested did not significantly affect skin cell differentiation or proliferation.
1 citations
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September 2024 in “Scientific Reports” This study observed that bacterial communities on scalp hair collected through non-invasive swabbing showed similar diversity and composition to those obtained by cutting or removing hair, suggesting that swabbing is an effective method for microbiome analysis on hair.
46 citations
,
May 2006 in “Laser Physics” In this study, particles similar in size to keratin cells were surprisingly found to penetrate more efficiently into hair follicles due to a possible pumping effect from moving hairs.
September 2023 in “Bioscience, biotechnology, and biochemistry” In this study, researchers observed that bacterial community structures on human scalp hair are unique to individuals and show consistent patterns across different sampling sites on the scalp, without significant variation between these sites.
8 citations
,
November 2022 in “International Journal of Cosmetic Science” This review discusses the limitations of current hair classification systems and highlights the need for standardized reporting of key hair characteristics to improve study comparisons; it reports no new results.
November 2025 in “Journal of Investigative Dermatology” Dark skin has stronger barriers and structure due to specific gene activity.
14 citations
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January 2015 in “Hormones and Cancer” This study found that androgen receptor inactivation in male and female mice reduced susceptibility to DMBA-induced skin cancer, but the effect varied by the carcinogenesis model.
6 citations
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September 2021 in “Experimental Brain Research” In this study, researchers found that the glabrous skin of the rat forelimb contains sparse Meissner corpuscles and Merkel complexes, with more slowly adapting afferents in the palm and rapidly adapting afferents in the digit extremity.
This study found that patients with androgenetic alopecia showed distinct scalp bacterial imbalances compared to healthy individuals, which were associated with unhealthy lifestyles. These microbial changes might contribute to follicular inflammation, potentially accelerating hair loss in these patients.
39 citations
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April 2020 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses the unique characteristics and disorders of Asian hair, emphasizing the need for more comprehensive studies in this area.
June 2023 in “Medeniyet medical journal” This study found that while the macular, retinal nerve fiber layer, and retinal layers' thickness were similar between alopecia areata patients and controls, the choroidal thickness was significantly thicker in the alopecia areata group, suggesting potential inflammation-related changes.
June 2026 in “Scientific Reports” This study found that alkyl shikimates with different alkyl group structures can increase or decrease fibroblast proliferation depending on concentration and alkyl chain length, with some variants showing cytotoxic effects due to their hydrophobicity and cell membrane permeability.
February 2025 in “Animals” In this review, researchers examined the molecular diversity and expression patterns of major skin appendage proteins, like keratins and EDC proteins, in tetrapods, highlighting recent findings in reptiles and birds and identifying knowledge gaps for future research.
48 citations
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August 1998 in “Journal of the American Academy of Dermatology” This review discusses the structural differences between black and white skin, noting that black skin has more compact stratum corneum, larger melanosomes, and increased transepidermal water loss.
January 1957 in “Nihon Chikusan Gakkaiho” This article examines microscopic structural differences and pigment distribution in various rabbit hair colors and reports no clinical results.
8 citations
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January 2020 in “PeerJ” This study found significant structural and compositional differences in hair affected by alopecia areata compared to healthy hair, using a range of physico-chemical investigation methods.
138 citations
,
November 1974 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society” This review explores the structural and functional sex differences in mammals beyond reproductive organs, highlighting variations in life expectancy, organ size, metabolism, and immune function, but it reports no new results.
March 2026 in “Skin Appendage Disorders” This narrative review highlights the distinct needs of pediatric hair care, emphasizing gentler formulations due to differences in children's hair physiology, structure, and barrier function, and calls for targeted regulations and research due to limited safety evidence.
2 citations
,
October 1992 in “PubMed” This study found no significant histologic differences in skin structure based on age, sex, or woodchuck hepatitis virus infection status among woodchucks.
1 citations
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November 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that male and female hair specimens show structural differences, with female hair having a brown color at the distal end and smooth surface texture, while male hair is completely black and shows surface irregularities; these differences may aid forensic analysis.
November 2024 in “Journal of Microscopy” This study found that micro-computed tomography (micro-CT) was highly effective for analyzing the cross-sectional geometry of hair fibres, including the medulla in highly curled hair, but less effective than scanning electron microscopy for surface details.
89 citations
,
January 2013 in “Acta dermato-venereologica” This review examines dandruff and seborrheic dermatitis, highlighting the role of Malassezia yeasts in inflammation and hyper-proliferation, and reports no new clinical findings.
4 citations
,
June 2022 in “Cold Spring Harbor Perspectives in Biology” This review discusses the heterogeneity of dermal fibroblasts in healthy mouse and human skin and reports no clinical results; the authors highlight potential insights into physiological and pathological wound healing.
In this study, researchers found that follicular and epidermal transglutaminases are biochemically and immunologically distinct, suggesting the possibility of selectively modifying hair or epidermal proteins.
January 2019 in “Hair transplant forum international” In this study, using sterile gloves during hair restoration surgery did not reduce scalp contamination compared to clean gloves due to the natural microbiome of the scalp.
73 citations
,
October 2013 in “International Journal of Cosmetic Science” This review examines the chemical composition and potential health risks of hair straighteners, but it reports no new findings and emphasizes the importance of understanding hair fibre structure for safe use.
53 citations
,
July 2016 in “Cosmetics” This study reviews the biology and cosmetic treatment of hair, emphasizing future advancements in safer, more effective procedures to meet consumer needs for hair care.
37 citations
,
January 1997 in “Journal of Pharmaceutical Sciences” This study observed that hairless rat skin was more permeable to mannitol and progesterone than hairy rat skin, indicating that follicular structures significantly impact percutaneous absorption.
February 2026 in “American Scientific Research Journal for Engineering, Technology, and Sciences (Global Society of Scientific Research and Researchers)” This study analyzed gray hair, revealing that it differs from pigmented hair in follicular activity, oxidative balance, and structure, impacting coloring processes and necessitating adapted techniques to maintain hair quality.
1 citations
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August 1992 in “Proceedings annual meeting Electron Microscopy Society of America” This research analyzed two ancient mammoth hair strands and reported distinct structural and elemental differences, including calcium, iron, and copper deposits, which vary with age and origin.