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    Glossary Stratum Spinosum

    layer of the epidermis with spiny-shaped keratinocytes

    The Stratum Spinosum, also known as the spinous layer or prickle cell layer, is a layer of the epidermis located just above the Stratum Basale. It consists of several layers of keratinocytes that are connected by desmosomes, which give the cells a spiny appearance under a microscope. This layer plays a crucial role in providing strength and flexibility to the skin.

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    1. Mitotic activity in the epidermis of the rabbit stimulated with local applications of testosterone propionate The journal of experimental zoology · 1949 · 25 citations
    2. Der Einfluβ des experimentellen Biotinmangels auf Morphologie und Histochemie von Haut und Klauen des Schweines Zentralblatt für Veterinärmedizin Reihe A · 1984 · 9 citations
    3. Multiphoton microscopic imaging of <i>in vivo</i> hair mouse skin based on two‐photon excited fluorescence and second harmonic generation Scanning · 2011 · 8 citations
    4. Age‐associated decrease in GDNF and its cognate receptor GFRα‐1 protein expression in human skin International journal of experimental pathology · 2016 · 2 citations
    5. Histological Study for Skin of Horse 2023
    6. A method on establishment of acne complex animal model Journal of Guangdong Pharmaceutical University · 2014
    7. Transplantation of Keratinocyte Spore-Like Stem Cells Transplantation · 2012
    8. Keratin 14 in skin and hair follicle of rats during postnatal development period Acta Academiae Medicine Militaris Tertiae · 2001
    9. A Spontaneous Fatp4/Scl27a4 Splice Site Mutation in a New Murine Model for Congenital Ichthyosis PLoS ONE · 2012 · 13 citations
    10. Biocompatible nanoparticles and vesicular systems in transdermal drug delivery for various skin diseases International Journal of Pharmaceutics · 2018 · 151 citations
    11. Focus on Skin as a Possible Port of Entry for Solid Nanoparticles and the Toxicological Impact Journal of biomedical nanotechnology · 2010 · 62 citations
    12. Ablative Fractional Resurfacing in Topical Drug Delivery: An Update and Outlook Dermatologic Surgery · 2013 · 55 citations
    13. Morphological characteristics and notes of the skin in preclinical toxicity assessment Journal of toxicologic pathology · 2022 · 2 citations
    14. Combined Ultrasound and Microneedle for Enhanced Transdermal Delivery: Synergistic Mechanisms and Therapeutic Advances BIO Integration · 2025 · 1 citations
    15. Microneedles-A new paradigm in transdermal delivery of therapeutic agents Pharmaceutical Sciences Asia · 2022 · 1 citations
    16. Influence of donor sources and culture media on the histo-morphological quality of human artificial skin models Online Publication Service of Würzburg University (Würzburg University) · 2018
    17. Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation Journal of Allergy and Clinical Immunology · 2019 · 34 citations
    18. A Novel Treatment of Acne Vulgaris Using a 1927 nm Fractional Thulium Laser: A Case Series Clinical Cosmetic and Investigational Dermatology · 2024 · 3 citations
    19. Human Eccrine Sweat Gland Cells Can Reconstitute a Stratified Epidermis Journal of Investigative Dermatology · 2010 · 103 citations
    20. Effects of Skin Lightening Cream Agents – Hydroquinone and Kojic Acid, on the Skin of Adult Female Experimental Rats Clinical Cosmetic and Investigational Dermatology · 2020 · 46 citations
    21. The acyl-CoA binding protein is required for normal epidermal barrier function in mice Journal of Lipid Research · 2012 · 31 citations
    22. The Necessity to Investigate In Vivo Fate of Nanoparticle-Loaded Dissolving Microneedles Pharmaceutics · 2024 · 14 citations
    23. Histomorphological and histochemical studies on the different layers of skin of Bakerwali goat Journal of Applied Animal Research · 2014 · 12 citations
    24. Positive Impact of Fish Oil on Diabetic and Hypercholestrolemic Skin Disorders Journal of nutrition & health · 2015 · 1 citations
    25. Microscopic anatomy of the skin of the woodchuck (Marmota monax): comparison of woodchuck hepatitis virus-infected and non-infected animals. PubMed · 1992 · 2 citations
    26. Cellular and Metabolic Basis for the Ichthyotic Phenotype in NIPAL4 (Ichthyin)–Deficient Canines American Journal Of Pathology · 2018 · 21 citations
    27. Anatomy and Physiology of the Skin Journal of the Dermatology Nurses’ Association · 2011 · 277 citations
    28. 3D printed microneedles: revamping transdermal drug delivery systems Drug Delivery and Translational Research · 2024 · 41 citations
    29. Review paper The use of reflectance confocal microscopy in selected inflammatory skin diseases Polish Journal of Pathology · 2015 · 20 citations
    30. Chemical Peels: Indications and Special Considerations for the Male Patient Dermatologic Surgery · 2017 · 15 citations