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    Glossary Stem Cell Exosomes

    tiny vesicles from stem cells aiding cell communication and repair

    Stem Cell Exosomes are tiny vesicles, or small bubble-like structures, released by stem cells that contain proteins, lipids, and genetic material. These exosomes play a crucial role in cell communication and can promote tissue repair and regeneration by transferring their contents to other cells, making them a promising tool in regenerative medicine and therapies for conditions like alopecia.

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    1. Human Amniotic Fluid Stem Cell-Derived Exosomes as a Novel Cell-Free Therapy for Cutaneous Regeneration Frontiers in Cell and Developmental Biology · 2021 · 74 citations
    2. Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing Stem cell research & therapy · 2023 · 28 citations
    3. Adipose-Derived Stem Cell Exosomes Promoted Hair Regeneration Tissue Engineering and Regenerative Medicine · 2021 · 19 citations
    4. Effects of exosome from adipose‐derived stem cell on hair loss: A retrospective analysis of 39 patients Journal of cosmetic dermatology · 2022 · 10 citations
    5. The efficacy of adipose stem cell‐derived exosomes in hair regeneration based on a preclinical and clinical study International Journal of Dermatology · 2024 · 2 citations
    6. Mesenchymal stem cell-derived exosomes ameliorate gentamicin-induced vestibular hair cell injury by regulating the SNARE pathway and enhancing autophagy Stem Cell Research & Therapy · 2025 · 1 citations
    7. The Anti-Aging Effects of Adipose-Derived Mesenchymal Stem Cell Exosomes on Skin and Their Potential for Personalized Skincare Applications Clinical Cosmetic and Investigational Dermatology · 2025 · 1 citations
    8. Chitosan Hydrogel Dressing Loaded with Adipose Mesenchymal Stem Cell-Derived Exosomes Promotes Skin Full-Thickness Wound Repair ACS applied bio materials · 2024 · 1 citations
    9. Dental pulp stem cell exosomes promote angiogenesis via the PI3K/Akt signaling pathway to treat androgenetic alopecia Stem Cell Research & Therapy · 2026
    10. Mesenchymal stem cell-derived exosomes promote scalp rejuvenation through type XVII collagen regulation via the miR-21-5p/DKK2/Wnt pathway Frontiers in Cell and Developmental Biology · 2026
    11. Hypoxia-Induced Mesenchymal Stem Cell-Derived Exosome Enhance TGF-β, PDGF, and Hair Growth in Alopecia-Like Rat Models Biosaintifika Journal of Biology & Biology Education · 2026
    12. Umbilical Cord Mesenchymal Stem Cell–Derived Exosomes Preserve Melanocyte Stem Cell Integrity Under Acute Neurogenic Oxidative Stress via Activation of the Nrf2– ARE Pathway in C57BL / 6J Mice Journal of Cosmetic Dermatology · 2026
    13. Human umbilical cord mesenchymal stem cell-derived exosomes enhance follicular regeneration in androgenetic alopecia via activation of Wnt/β-catenin pathway Stem Cell Research & Therapy · 2025
    14. Mesenchymal Stem Cell-Derived Exosomes Can Effectively Improve the Hair Count and Terminal Hair Diameter in Androgenetic Alopecia Research Square (Research Square) · 2025
    15. Potential of mesenchymal stem cell-derived exosomes in the treatment of androgenetic alopecia World Journal of Stem Cells · 2025
    16. Mesenchymal stem cell exosomes enhance the development of hair follicle to ameliorate androgenetic alopecia World Journal of Stem Cells · 2025
    17. Exosomes derived from Umbilical cord mesenchymal stem cell promote hair regrowth in C57BL6 mice through upregulation of the RAS/ERK signaling pathway Journal of Translational Internal Medicine · 2024
    18. EXPLORING THE EFFICACY AND THERAPEUTIC POTENTIAL OF MESENCHYMAL STEM CELL–DERIVED EXOSOMES FOR THE TREATMENT OF ANDROGENIC ALOPECIA 2024
    19. 23 Efficacy of combined treatment with adipose tissue stem cell exosomes (ASCE) and microneedling for facial skin aging: a 12-week prospective, randomized, split-face study 2023
    20. 21 Adipose stem cell exosome (ASCE): next generation regenerative aesthetics & therapeutics for scalp & hair Journal of Investigative Dermatology · 2023
    21. Adipose-Derived Stem Cell Exosomes Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicle Growth by Activating Wnt/β-Catenin Pathway Stem Cells International · 2023
    22. 1615 Adipose stem cell exosome (ASCE): Next generation regenerative aesthetics & therapeutics for scalp & hair Journal of Investigative Dermatology · 2023
    23. Stem Cell-Derived and Plant-Derived Exosomes: Promising Therapeutics for Skin Healing and Regeneration Molecular and Cellular Probes · 2026
    24. CellTissueScience 2018: Innovations in regenerative medicine that improve the results of stem cell treatment: 3D cultivation, in vivo modeling of stem cell niche and prenatal stem cells exosomes_AbhijitBopardikar_ReeLabs Pvt. Ltd., India Cell & developmental biology · 2019
    25. Therapeutic potential of stem cell-derived exosomes in hair regeneration: A systematic review World Journal of Stem Cells · 2025
    26. Human hair follicle mesenchymal stem cell-derived exosome attenuates UVB-induced photoaging via the miR-125b-5p/TGF-β1/Smad axis Biomaterials Research · 2024
    27. 19 Adipose stem cell exosome (ASCE): next generation regenerative therapeutics for atopic dermatitis Journal of Investigative Dermatology · 2023
    28. Hypoxia-Derived Mesenchymal Stem Cell Exosomes Downregulate CXCL12 and Upregulate IL-10 Expression in a Murine Model of Androgenic Alopecia Molecular and Cellular Biomedical Sciences · 2026
    29. Stem Cell Secretome for Skincare: Of Cell Types, Exosomes, Extracellular Vesicles, and Soluble Fractions Preprints.org · 2025
    30. Efficacy of Placental-Derived Mesenchymal Stem Cell Exosome Therapy in Treating Androgenetic Alopecia: A Clinical Trial Study Research Square (Research Square) · 2024