January 2001 in “China Surfactant Detergent & Cosmetics” This study compared the protective effects of two conditioners, Protective factor C and Keratin, on hair damaged by perm treatment using a model of damaged hair.
March 2026 in “DergiPark (Istanbul University)” In this study, BTP-loaded solid lipid nanoparticles were developed and shown to protect hair from heat-induced damage by enhancing cuticle integrity and thermal resistance in simulated thermal straightening conditions.
Hair restoration can be permanent.
January 2015 in “Springer eBooks” This review discusses the transition of healthy hair to an unhealthy state due to structural and physiological disruptions, but reports no new results.
7 citations
,
October 2019 in “Frontiers in bioengineering and biotechnology” This study found that pretreatment with KP-Cryst fusion proteins effectively protected Asian and Caucasian virgin hair from thermal damage by maintaining higher water content and preventing structural changes during heat application.
3 citations
,
January 2004 in “Sen i Gakkaishi” This study found that adding dithiodiglycolic acid to the hair straightening process decreased chemical damage and preserved the structural integrity of the hair matrix compared to using thioglycolic acid alone.
January 2024 in “Skin Appendage Disorders” This source reports that SET may offer notable cosmetic improvements and enhance well-being for patients with CA, serving as a cost-effective treatment option either alone or alongside hair transplantation.
April 2018 in “Journal of Investigative Dermatology” This study found that the absence of Hes1 in hair follicles delays secondary hair germ activation and shortens the anagen phase, impacting HFSC self-renewal and long-term hair regeneration.
1 citations
,
March 2019 in “International Journal of Cosmetic Science” In this study, researchers developed a regression model that reasonably predicts consumer-perceived hair breakage using various parameters such as hair smoothness, detangling forces, extensional strength, and hair density among Indian women.
January 2011 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” This study found that a combination of spermidin, rutine, and zeaxantine effectively reduced staurosporin-induced apoptosis in cultured hair follicle dermal papilla cells, potentially preventing the regression phase in the hair follicle cycle.
6 citations
,
January 2000 in “Dermatology” A girl's severely tangled hair couldn't be fixed and had to be cut due to a rare condition called plica neuropathica.
May 2026 in “International Journal of Cosmetic Science” In this study, researchers observed that using an Avena strigosa seed extract on chemically damaged hair significantly improved hair properties, including strength, gloss, and surface quality, by reinforcing keratin bonding and sealing cuticle damage.
11 citations
,
January 1999 in “Dermatologic Surgery” The researchers reported that using extenders during scalp reductions increased effectiveness by 30 to 86% and prevented "stretch-back" in subsequent procedures.
4 citations
,
January 2017 in “Annals of Dermatology” Frequent hairdryer use may worsen hair fragility in people with Pili Annulati.
9 citations
,
June 2014 in “Journal of Craniofacial Surgery” The authors concluded that using an expanded temporoparieto-occipital scalp flap for sideburn reconstruction provides satisfactory hair direction and inconspicuous scars in both the donor and recipient areas, with few complications.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that prostaglandin E2 pretreatment may reduce radiotherapy-induced alopecia by enhancing hair follicle self-repair through transient G1 arrest, suggesting a potential preventive treatment.
April 2018 in “Radiotherapy and Oncology” Prostaglandin helps regenerate hair follicles after radiation damage.
June 2024 in “ChemBioChem” This study's simulations suggest that replenishing free 18‐MEA could restore damaged hair surface properties, highlighting the importance of optimal fatty acid spacing for maintaining hair integrity.
1 citations
,
June 2023 in “Sciential - McMaster Undergraduate Science Journal” This paper reviews scalp cooling as an effective method for preventing chemotherapy-induced alopecia, highlighting recent trials that demonstrate its ability to preserve and regrow hair, thus improving patient well-being.
11 citations
,
November 2005 in “Hair transplant forum international” This article discusses shock loss as a consequence of hair restoration procedures but reports no scientific data on occurrence rates.
July 2024 in “Journal of Investigative Dermatology”
3 citations
,
January 2011 in “Wspolczesna Onkologia-Contemporary Oncology” Scalp hypothermia can prevent chemotherapy-induced hair loss but is not suitable for all patients, and more research is needed to improve prevention methods.
July 2026 in “Journal of Investigative Dermatology”
10 citations
,
April 2010 in “Dermatologic Surgery” This paper contains no findings, serving instead as contact information for a dermatologist with no financial conflicts of interest disclosed.
January 2026 in “Colloids and Surfaces B Biointerfaces” This study found that treating damaged hair with maleic-modified amino silicone oil created a highly hydrophobic surface, reducing water content and improving hair's mechanical properties and thermal stability.
April 2025 in “Brazilian Journal of Hair Health” This report from Tangle Teezer and TRI Princeton indicates that their Extra Gentle brush reduces hair breakage by up to 39%, offering a therapeutic experience for users with fragile scalps.
November 2008 in “Medical & surgical dermatology” This study reports that a prototype device may accurately measure changes in hair quantity, diameter, and density in patients with balding by assessing the cross-sectional area of hair bundles.
This review synthesizes evidence on strategies to preserve donor aesthetics and reserve in follicular unit extraction, emphasizing conservative extraction limits and long-term planning to prevent donor site morbidity.
February 2003 in “Dermatology Times” According to this study, hair diameter diversity and peripilar signs can predict future hair loss in early-stage androgenic alopecia.