1 citations
,
October 2013 in “BMJ” This case study reports a man with rapid hair thinning, whitening, and sparse beard, linked to an increased proportion of hair follicles in catagen or telogen phase and peribulbar lymphocytic infiltrate.
44 citations
,
August 2004 in “Journal of Investigative Dermatology” A gene deletion in DSG4 causes sparse hair in some Pakistani families.
33 citations
,
October 2005 in “Journal of Investigative Dermatology” A specific gene mutation causes sparse, brittle hair in a family.
January 2015 in “The Encyclopedia of Clinical Psychology” This review discusses trichotillomania treatments, highlighting that habit reversal training shows promise for children and adolescents, although further research is needed, as existing literature on this age group is sparse.
January 2026 in “Clinical Case Reports” This case report describes a 6-year-old girl diagnosed with the rare concurrence of monilethrix and trichorrhexis nodosa, characterized by sparse, brittle hair, who showed minimal clinical improvement with low-dose oral and topical minoxidil treatment.
December 2025 in “Frontiers in Medicine” This review details the global mutation patterns of genes associated with autosomal recessive woolly hair/hypotrichosis and highlights potential, yet unproven, treatments like minoxidil and regenerative therapies, reporting no new clinical results.
January 2012 in “International Journal of Trichology” Two siblings have a rare genetic condition causing curly, coarse hair.
December 2025 in “Clinical Case Reports” In this study, researchers reported that dermoscopic examination of eyebrow hairs can help in the early diagnosis of Netherton syndrome in children by detecting trichorrhexis invaginata, facilitating prompt counseling and care while awaiting genetic test results.
5 citations
,
January 2018 in “Acta Dermatovenerologica Alpina Pannonica et Adriatica” This case study highlights congenital atrichia with papular lesions as a cause of total body hair loss, characterized by the absence of hair follicles and the presence of skin-colored papules.
June 2026 in “International Journal of Homoeopathic Sciences” In this case report, the researchers observed that a woman with longstanding Alopecia Universalis, who had not responded to various treatments, experienced hair regrowth and improved quality of life after two years of individualized homeopathic treatment centered around Natrum Muriaticum.
25 citations
,
October 1996 in “Dermatologic Clinics” This article discusses loose anagen syndrome, highlighting its characteristics, diagnostic methods, and spontaneous improvement over time, but provides no new clinical results.
8 citations
,
July 2014 in “Anais Brasileiros de Dermatologia” This article discusses a case of alopecia areata, androgenetic alopecia, and trichostasis spinulosa, highlighting how dermoscopy can help differentiate black dots from trichostasis spinulosa lesions, but it reports no new clinical results.
8 citations
,
January 2003 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy” This case report documents a cancer survivor who experienced cyclic alopecia areata following chemotherapy, suggesting potential autoimmune changes related to the treatment.
7 citations
,
July 2011 in “Survey of Ophthalmology” This guide provides a comprehensive approach to diagnosing periocular hair disorders, which can range from benign conditions to those posing serious health risks.
54 citations
,
January 1983 in “Archives of Dermatology” This article presents two cases of keratosis follicularis spinulosa decalvans and reviews its features, highlighting characteristic progression from keratosis pilaris in infancy to cicatricial alopecia in childhood.
15 citations
,
August 2019 in “Dermatologic Therapy” This letter details a case report on platelet-rich plasma treatment for a patient with treatment-resistant frontal fibrosing alopecia, but it does not provide new clinical results.
5 citations
,
December 1964 in “Australasian journal of dermatology” This article discusses congenital atrichia and presents no new clinical findings.
1 citations
,
April 2025 in “Pediatria i Medycyna Rodzinna” This research re-analyzed single-cell gene expression data from a mouse model, confirming that certain genes involved in the EDA-EDAR and WNT pathways are crucial for skin appendage development, suggesting that their restoration may mitigate the effects of hypohidrotic ectodermal dysplasia in children.
August 2021 in “Journal of medical science and clinical research” This case report describes an 11-month-old infant with Biotinidase deficiency who exhibited multifocal seizures, neuroregression, alopecia, and skin issues, highlighting prompt diagnosis and the dramatic clinical response to biotin treatment.
49 citations
,
January 2003 in “Clinical and Experimental Dermatology” This report from the UK reviews the literature on post-menopausal frontal fibrosing alopecia and highlights its under-recognition and distinctive characteristics compared to lichen planopilaris, but does not provide new results.
14 citations
,
January 2006 in “Australasian journal of dermatology” This case report describes an atypical presentation of alopecia areata in a 53-year-old postmenopausal woman, which may resemble frontal fibrosing alopecia and complicate diagnosis.
5 citations
,
November 2020 in “Forensic Science International Genetics” This study found that using trait prevalence-informed priors may improve the prediction accuracy of appearance traits in Bayesian models, but their application is limited by sparse knowledge on trait prevalence.
2 citations
,
April 2017 in “Actas Dermo-Sifiliográficas” This review discusses the etiology, pathogenesis, clinical presentation, and treatment of frontal fibrosing alopecia, noting the lack of clinical trial data and limited observational treatment results.
January 2013 in “The Pan African medical journal” This report describes two cases of monilethrix in Afghan siblings, detailing the hair disorder's clinical presentation and potential influences on hair growth, such as hormonal changes and iron supplementation.
15 citations
,
May 2013 in “American Journal of Medical Genetics - Part A” People with X-linked hypohidrotic ectodermal dysplasia have no sweat ducts and less, thinner hair.
3 citations
,
February 2022 in “Cureus” This study observed an alopecia syphilitica-like pattern of hair loss in a woman with frontal fibrosing alopecia, suggesting it may be another atypical presentation of the condition.
January 2019 in “Global Dermatology” This review discusses the genetic disorder, monilethrix, characterized by fragile, brittle hair and its inheritance patterns, and reports no new clinical results.
38 citations
,
July 1998 in “Journal of surgical oncology” This review discusses acquired hypertrichosis lanuginosa, a rare disorder often linked to internal malignancy, and reports no new clinical findings; the authors highlight proposed pathogenic mechanisms for lanugo hair overgrowth.
17 citations
,
June 2017 in “British Journal of Dermatology” This review examines the interaction between hedgehog and Wnt/β-catenin signalling in hair follicles and basal cell carcinoma, linking Hh pathway inhibition to both tumor regression and alopecia.
15 citations
,
February 2015 in “Cell & tissue research/Cell and tissue research” This review examines the role of P-cadherin in skin and hair biology, emphasizing its importance in human hair growth, cycling, and pigmentation, and reports no new research findings.