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    Glossary SMAD proteins

    proteins that transmit signals from cell surface to nucleus

    SMAD proteins are a group of molecules that play a crucial role in transmitting signals from the cell surface to the nucleus. They are involved in the TGF-beta signaling pathway, which regulates various cellular processes such as growth, differentiation, and apoptosis. Essentially, they act as messengers that help cells respond to external signals, ensuring proper cellular function and development.

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    Research 30 of 959

    1. iTRAQ-based quantitative proteomics revealing the therapeutic mechanism of a medicinal and edible formula YH0618 in reducing doxorubicin-induced alopecia by targeting keratins and TGF-β/Smad3 pathway Heliyon · 2024
    2. MON-203 Dermatological Effects Of Hormone Replacement Therapy Journal of the Endocrine Society · 2025
    3. Ligand-Dependent Actions of the Vitamin D Receptor Are Required for Activation of TGF-β Signaling during the Inflammatory Response to Cutaneous Injury Endocrinology · 2012 · 56 citations
    4. Effects of dihydrotestosterone on rat dermal papilla cells in vitro European Journal of Pharmacology · 2015 · 19 citations
    5. Camellia sinensis Seed Flavonoids Attenuate UVB-Induced Inflammation and UVA-Induced Photodamage via MAPK/NF-κB and AP-1 Pathways Molecules · 2026
    6. The Roles of Smad2 and Smad3 in Mouse Skin Development The Knowledge Bank (The Ohio State University) · 2008
    7. Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma Oncotarget · 2018 · 11 citations
    8. 4-<i>O</i>-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling Biomolecules & Therapeutics · 2017 · 5 citations
    9. Stem Cell-Derived Extracellular Vesicles: Promising Therapeutic Opportunities for Diabetic Wound Healing International Journal of Nanomedicine · 2024 · 12 citations
    10. Network pharmacology and in vivo experimental analysis for validating the antifibrotic potential of Punica granatum leaves against skin scleroderma: the role of oxidative stress, inflammation and TGF-β1/Snail 1/p-Smad 3 signaling pathway Inflammopharmacology · 2026
    11. Decorin-mediated dermal papilla cell-derived exosomes regulate hair follicle growth and development through miR-129-2-3p/SMAD3/TGF-β axis International Journal of Biological Macromolecules · 2025
    12. The high-polarity fraction of tail fat derived from Lanzhou Fat-Tailed sheep enhances skin wound healing through the regulation of inflammatory factors and the TGF-β1/Smad3 signaling pathway Food Science and Human Wellness · 2026
    13. Kaempferol enhances hair growth by regulating JAK3/STAT6 and TGF-β/Smad signaling in human dermal papilla cells and a C57BL/6 mousemodel Records of Natural Products · 2025
    14. Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway International Journal of Molecular Sciences · 2023
    15. Hair follicle development and related gene and protein expression of skins in Rex rabbits during the first 8 weeks of life Asian-Australasian Journal of Animal Sciences · 2018 · 14 citations
    16. Aconiti Lateralis Preparata Radix Activates the Proliferation of Mouse Bone Marrow Mesenchymal Stem Cells and Induces Osteogenic Lineage Differentiation through the Bone Morphogenetic Protein-2/Smad-Dependent Runx2 Pathway Evidence-based Complementary and Alternative Medicine · 2013 · 18 citations
    17. SIRT1-modified human umbilical cord mesenchymal stem cells ameliorate experimental peritoneal fibrosis by inhibiting the TGF-β/Smad3 pathway Stem Cell Research & Therapy · 2020 · 17 citations
    18. All-trans-retinoic acid inhibits mink hair follicle growth via inhibiting proliferation and inducing apoptosis of dermal papilla cells through TGF-β2/Smad2/3 pathway Acta histochemica · 2020 · 10 citations
    19. Stem Cells and their Niches Journal of Investigative Dermatology · 2013 · 1 citations
    20. TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition Cold Spring Harbor Perspectives in Biology · 2017 · 82 citations
    21. Transforming growth factor-β in stem cells and tissue homeostasis Bone Research · 2018 · 245 citations
    22. Transgenic mice overexpressing CD109 in the epidermis display decreased inflammation and granulation tissue and improved collagen architecture during wound healing Wound Repair and Regeneration · 2013 · 22 citations
    23. Epimorphic regeneration in mice is p53-independent Cell Cycle · 2010 · 20 citations
    24. Linking diet to acne metabolomics, inflammation, and comedogenesis: an update Clinical, Cosmetic and Investigational Dermatology · 2015 · 138 citations
    25. Wound healing mechanism in Mongolian gerbil skin Histochemistry and Cell Biology · 2018 · 6 citations
    26. Expression of truncated latent TGF-β-binding protein modulates TGF-β signaling Journal of Cell Science · 2005 · 40 citations
    27. P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression Stem Cell Research & Therapy · 2016 · 24 citations
    28. Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation Cell stem cell · 2012 · 321 citations
    29. Preliminary study on microR-148a and microR-10a in dermal papilla cells of Hu sheep BMC Genetics · 2019 · 28 citations
    30. Atelocollagen Increases Collagen Synthesis by Promoting Glycine Transporter 1 in Aged Mouse Skin International Journal of Molecular Sciences · 2025 · 1 citations