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The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

A girl with rickets and hair loss was found to have a rare condition where her body didn't respond to vitamin D treatment.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Platelet-rich plasma may have some benefits in dermatology, but there's not enough evidence to widely recommend its use.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

New genes and pathways are important for testosterone production and male sexual development.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Nonionic liposomes are the best for delivering genes to skin cells.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

Low iron and vitamin D levels are linked to hair loss in women.