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    Did you mean Single-cell RNA sequencing?
    Glossary Single-cell RNA sequencing

    examines gene expression in individual cells for detailed insights

    Single-cell RNA sequencing (scRNA-seq) is a powerful technique that allows scientists to examine the gene expression profiles of individual cells. This method provides detailed insights into the cellular diversity within a tissue, revealing how different cells function and interact, which is crucial for understanding complex biological processes and diseases like cancer or alopecia.

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    Research 30 of 1000+

    1. 164 Epigenetic and transcriptional profiling of PBMCs in mild and severe alopecia areata using single-cell RNA-Seq and ATAC-Seq Journal of Investigative Dermatology · 2023
    2. Single-cell chromatin landscapes of mouse skin development Scientific Data · 2022 · 2 citations
    3. Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease bioRxiv (Cold Spring Harbor Laboratory) · 2022
    4. States and Fates of Skin Fibroblasts Revealed through Chromatin Accessibility Journal of Investigative Dermatology · 2022
    5. Single cell analysis of transcriptome and open chromatin reveals the dynamics of hair follicle stem cell aging Frontiers in Aging · 2023 · 3 citations
    6. Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing Cell stem cell · 2020 · 128 citations
    7. 1418 Characterization of ectomesenchyme as an origin of epidermal stem cells Journal of Investigative Dermatology · 2023
    8. Fibroblast heterogeneity and functions: insights from single-cell sequencing in wound healing, breast cancer, ovarian cancer and melanoma Frontiers in genetics · 2024
    9. Single-Cell Sequencing Technology in Ruminant Livestock: Challenges and Opportunities Current Issues in Molecular Biology · 2024 · 5 citations
    10. Molecular heterogeneity of quiescent melanocyte stem cells revealed by single‐cell RNA‐sequencing Pigment cell & melanoma research · 2024
    11. CXCL12 Drives Reversible Fibroimmune Remodeling in Androgenetic Alopecia Revealed by Single-Cell RNA Sequencing International Journal of Molecular Sciences · 2025
    12. scMC learns biological variation through the alignment of multiple single-cell genomics datasets Genome biology · 2021 · 822 citations
    13. Exploring machine learning strategies for single-cell transcriptomic analysis in wound healing Burns & Trauma · 2025 · 5 citations
    14. Stem cell dynamics, migration and plasticity during wound healing Nature Cell Biology · 2018 · 211 citations
    15. The molecular anatomy of cashmere goat hair follicle during cytodifferentiation stage BMC Genomics · 2024
    16. Prediction of cell states and key transcription factors of the human cornea through integrated single-cell omics analyses PNAS Nexus · 2025
    17. Advances in single-cell transcriptomics in animal research 2024 · 21 citations
    18. Skin fibroblast functional heterogeneity in health and disease The Journal of Pathology · 2023 · 1 citations
    19. Epithelial-Mesenchymal Micro-niches Govern Stem Cell Lineage Choices Cell · 2017 · 214 citations
    20. Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata Frontiers in Immunology · 2025 · 4 citations
    21. A multi-omic single-cell landscape of perinatal mouse skin maps lineage specification and reveals shared dynamics in human fetal skin Experimental & Molecular Medicine · 2026
    22. From bedside to bench: regulation of host factors in SARS-CoV-2 infection Experimental and Molecular Medicine · 2021 · 4 citations
    23. Single-Cell Omics Advances in Understanding Tissue Development and Complex Trait Formation in Sheep and Goats Animals · 2026
    24. Wound Healing: A Cellular Perspective Physiological Reviews · 2018 · 1160 citations
    25. Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases Nature Genetics · 2023 · 47 citations
    26. Gene trajectory inference for single-cell data by optimal transport metrics Nature Biotechnology · 2024 · 32 citations
    27. Deciphering gene regulatory programs in mouse embryonic skin through single-cell multiomics analysis Genome biology · 2025
    28. Transcriptional and epigenetic mechanisms governing epidermal stem cell regulation Frontiers in Cell and Developmental Biology · 2026
    29. Investigation of Transcriptional Gene Profiling in Normal Murine Hair Follicular Substructures Using Next-Generation Sequencing to Provide Potential Insights into Skin Disease Cell Transplantation · 2016 · 1 citations
    30. Integrated multiomics analysis reveals the molecular features and crucial regulators of hair follicles in yak (Bos grunniens) Communications Biology · 2026