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research Serenoa Repens (Saw Palmetto) for Lower Urinary Tract Symptoms (LUTS): The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part III
This review concludes that global literature supports the lipidosterolic extract of Serenoa repens as efficacious and safe for treating lower urinary tract symptoms, with some studies showing equivalence to common pharmacologic agents.
research Successful Topical Treatment of Murine Cutaneous Leishmaniasis with a Combination of Paromomycin (Aminosidine) and Gentamicin
This study found that all lesions in mice treated with a new topical formulation, WR 279,396, healed completely without relapse, outperforming other formulations and showing no toxicity.
research Dietary Supplements in Chemotherapy-Induced Peripheral Neuropathy: A New Hope?
This review discusses potential agents, including acetyl-L-carnitine and vitamins, for repurposing in managing chemotherapy-induced peripheral neuropathy and reports no clinical results; the authors emphasize the need for further research.
research Amiodarone-Induced Toxic Epidermal Necrolysis; Nilotinib-Associated Cerebrovascular Disease and Stroke; Pisa Syndrome Caused by Paliperidone; Macroglossia Associated with Methylprednisolone; Aromatase Inhibitor-Induced “Male Pattern Baldness” in Women? Acute Liver Failure Due to Etodolac
This article discusses the importance of recognizing adverse drug reactions, methods of prevention, and encourages reporting them to the FDA's MedWatch program; it reports no new results.
research 554 Repurposing a clinical antimalarial for the therapeutic induction of lethal ER stress targeting BRAF-kinase inhibitor-resistant malignant melanoma
This study identified mefloquine as a potent inducer of lethal ER stress that effectively eliminated vemurafenib-resistant and sensitive melanoma cells, suggesting its potential for repurposing as a melanoma treatment.
research Health Canada has approved finasteride [Proscar; Merck Frosst] and doxazosin cotherapy
research Cognitive and mood side effects of lower urinary tract medication
This review examines the cognitive effects of medications for lower urinary tract symptoms and indicates that muscarinic antagonists, particularly oral oxybutynin, pose the highest risk for cognitive impairment.
research Nilotinib-induced generalized keratosis pilaris: Report of a rare case
This case study reports generalized keratosis pilaris as a rare cutaneous side effect of nilotinib in a 40-year-old woman with chronic myeloid leukemia, highlighting the need for awareness among physicians.
research Tales of bugs, delusions of parasitosis, and what to do
This study presents four cases of delusions of parasitosis and introduces escitalopram as a potential therapy, highlighting its fewer side effects compared to the commonly used pimozide.
research Hair Loss Associated with Teriflunomide Treatment
Teriflunomide can cause hair thinning.
research 371 THE EFFECTIVENESS OF BIO-REGULATORY MAGNETO-LASER THERAPY OF CHRONIC PELVIC PAIN SYNDROME/CHRONIC PROSTATITIS IMA
research A review on therapeutic effect of Siddha classical formulation Seenthil Chooranam
This review found that Seenthil Chooranam, a traditional Siddha formulation, has potential therapeutic benefits for various diseases due to its pharmacological properties and bioactive compounds, though further research is needed to confirm its safety and clinical effectiveness.
research 08.33 Treatment of rheumatoid arthritis patients: comparative efficacy of four treatment regimens
This study, involving patients with early rheumatoid arthritis, found that treatment regimens combining methotrexate and glucocorticoids, with or without initial high-dose methylprednisolone, showed higher remission rates over one year compared to methotrexate or leflunomide alone, and all regimens were generally well-tolerated.
research A10.09 Safety data of four treatment regimens in early rheumatoid arthritis patients
In this study, the researchers reported that the safety profile was similar across all DMARD treatment regimens for early rheumatoid arthritis, but the most severe side effects occurred in the leflunomide group.