228 citations
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February 2003 in “Urology” This article discusses the side effects of androgen deprivation therapy for nonmetastatic prostate cancer, highlighting the need for clinical trials to systematically study these effects.
80 citations
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January 1988 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study observed that high-dose spironolactone frequently caused metrorrhagia in women with idiopathic hirsutism, leading the authors to suggest lower starting doses or additional hormonal therapy.
55 citations
,
December 1983 in “Acta Neurologica Scandinavica” This review discusses the side effects of carbamazepine, valproate, and clonazepam, noting that these are rare with long-term use but more common, transient, and generally mild during early treatment.
46 citations
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December 1997 in “Cancer Nursing” In this study, patients receiving CHOP chemotherapy for aggressive non-Hodgkin's lymphoma reported a wide range of side effects, with all experiencing hair loss by cycle 3 and fatigue as a common issue.
38 citations
,
November 2012 in “Expert Opinion on Drug Safety” This article reviews different acne treatments and emphasizes the importance of being aware of their potential side effects, but reports no new clinical results.
35 citations
,
April 2013 in “Sexual medicine reviews” This review found that 5α-reductase inhibitors are associated with slightly increased rates of sexual dysfunction, gynecomastia, and mood disorders, but the true significance and persistence of these effects remain unclear.
18 citations
,
January 2009 in “Acta neurologica Scandinavica” In this study, the side effects of long-term sodium valproate treatment for refractory epilepsy were generally slight and transient, with severe side effects not observed.
11 citations
,
January 1980 in “PubMed” This article reviews various side effects and concerns related to oral contraceptives, including potential vascular complications and elevated plasma cortisol levels, but reports no new clinical results.
7 citations
,
June 2020 in “JAAD Case Reports” This article reviews the development of biocompatible artificial hair for treating hair loss and reports encouraging results from clinical trials, but it provides no new clinical findings.
6 citations
,
January 2021 in “Journal of The American Academy of Dermatology” This letter discusses adverse events related to low-dose oral minoxidil for alopecia, highlighting age-related risks and stressing the importance of contraindication awareness with no new clinical results presented.
6 citations
,
April 2016 in “PubMed” This review found that dutasteride and finasteride are rarely associated with sexual side effects when used off-label for female hair loss, and suggests further study of their efficacy and side effect profile.
3 citations
,
April 2017 in “Zahedan Journal of Research in Medical Sciences” This study observed that nearly all kidney transplant patients experienced complications from immunosuppressive therapy, with excessive hair growth and increased blood sugar being the most common issues.
2 citations
,
July 2023 in “Journal of Education Health and Sport” This review article summarizes potential side effects of microneedle mesotherapy, including both infectious and non-infectious complications such as bruises, swelling, anaphylaxis, and skin necrosis, emphasizing that awareness and proper technique may mitigate these risks.
2 citations
,
June 2021 in “Immunopathologia Persa” This study observed that among Iranian patients with rheumatoid arthritis, methotrexate treatment was discontinued or reduced in nearly half of the cases due to side effects such as nausea, flu-like symptoms, hepatotoxicity, and hair loss, with hepatotoxicity linked to higher doses and longer treatment duration.
This study found that perceptions of scalp micropigmentation and awareness of its side effects vary significantly by gender and age, influencing attitudes and intentions toward the procedure.
November 2025 in “Cureus” This study found that COVID-19 vaccines were generally well-tolerated among Bangladeshi medical students, with most side effects being mild and decreasing in frequency after subsequent doses.
July 2024 in “Skin Appendage Disorders” In this study, researchers found that low-dose oral minoxidil for androgenetic alopecia in men generally showed a good safety profile, with hypertrichosis being the most frequent side effect, while systemic side effects like dizziness and hypotension were less common and no life-threatening effects were observed.
This observational study reviewed thyroid eye disease patients treated with teprotumumab at one center, reporting common side effects like fatigue and dry eye symptoms, with serious adverse events including two cases of blood clots and one pulmonary embolism.
January 2023 in “Side effects of drugs annual” This chapter reviews emerging side effects of various nutritional supplements and alternative medicine practices, highlighting potential toxicities and stressing the need for careful identification and management by healthcare professionals.
November 2020 in “Universal Journal of Pharmaceutical Research” In this study, tacrolimus-based treatment was found to result in fewer overall side effects compared to cyclosporine among Yemeni kidney transplant patients, although tacrolimus was associated with a higher incidence of diabetes.
July 2020 in “Scholars journal of applied medical sciences” This study found that vomiting was the most common side effect of sodium valproate in children under two with epilepsy.
This study describes a computational method using side-effect data from social media to identify new drug indications, suggesting it could be effective for drug repositioning.
September 2025 in “Journal of the American Academy of Dermatology” This study explores patients' perceptions of hair loss treatments, specifically oral minoxidil, topical minoxidil, and oral finasteride, building on existing clinical research.
1108 citations
,
January 2018 in “Dalton transactions” This review discusses the multiple severe side effects of cisplatin, carboplatin, and oxaliplatin in cancer treatment and reports no new clinical results; the authors emphasize the need for careful monitoring and supportive care to manage these effects.
225 citations
,
July 2007 in “The Journal of Sexual Medicine” In this study, patients informed about finasteride's potential sexual side effects reported a significantly higher occurrence of these side effects, suggesting a nocebo effect.
223 citations
,
December 2010 in “The Journal of Sexual Medicine” This review discusses persistent adverse effects of 5α‐reductase inhibitors, like diminished libido and erectile dysfunction, in some patients and highlights the need for patient discussions before therapy, especially for androgenetic alopecia.
179 citations
,
October 2018 in “American Journal of Clinical Dermatology” This review outlines various dermatologic adverse events associated with targeted therapies and immunotherapies, emphasizing the need for collaboration between dermatologists and oncologists to manage these effects effectively; it reports no new clinical findings.
116 citations
,
December 2003 in “Acta Dermato Venereologica” This study reports that Iressa, an anti-cancer agent, commonly causes acneiform eruptions and xerosis as cutaneous side effects, similar to other agents targeting epidermal growth factor receptors.
73 citations
,
July 2013 in “The Journal of Sexual Medicine” This study observed that androgenic alopecia patients taking finasteride had altered neuroactive steroid levels and persistent depression symptoms even after stopping the treatment.
55 citations
,
November 2004 in “Expert opinion on drug safety” This review describes the variety of mucocutaneous side effects caused by antineoplastic chemotherapy, with emphasis on skin, nails, and mucous membranes, while highlighting potential severity and the possibility of needing to adjust or interrupt treatment in rare cases; it presents no new clinical results.