April 2024 in “Research Square (Research Square)” In this randomized trial, lupus patients taking daily 200 μg selenium supplements for eight weeks showed significant improvements in metabolic markers like CRP, ESR, MDA, and GPX, as well as reduced clinical symptoms such as arthritis and alopecia, compared to those receiving a placebo.
February 2024 in “Journal of Geochemical Exploration” Selenium levels in soil, crops, and human hair in Northwest China are within safe limits.
October 2023 in “Èkologiâ čeloveka” People in Moldova have less selenium in their hair than recommended, which may contribute to hair loss.
June 2023 in “Skin Research and Technology” The researchers reported that an oral supplement containing hydrolysed fish-origin collagen, taurine, cysteine, methionine, iron, and selenium significantly improved the effectiveness of anti-hair loss treatments in people with androgenic alopecia or chronic telogen effluvium after 12 weeks, compared to drug treatments alone.
April 2023 in “Acta Poloniae Pharmaceutica” This study found that using Urtica cannabina extract shampoo led to increased levels of copper, zinc, and iodine in the scalp hair of Mongolian women, along with improvements in hair growth, diameter, and density compared to a regular shampoo.
February 2023 in “European journal of geriatrics and gerontology” Selenium helps prevent thyroid issues and cognitive decline in the elderly, but balance is key.
January 2021 in “Agrobiological records” This review paper examined recent research on the biofortification of horticultural plants, such as fruits and vegetables, with selenium, highlighting their role in addressing selenium deficiencies and supporting various biological functions crucial to human health.
This study found that four bacterial isolates from a microbiology laboratory collection demonstrated resistance to selenate, with molecular analysis showing they closely resemble different strains of Bacillus megaterium.
The levels of zinc, vitamin D, ferritin, and selenium are different in people with androgenic alopecia compared to a control group.
January 2018 in “ScholarWorks @UVM (University of Vermont)” This study provides evidence supporting the theory that the presence of selenocysteine in proteins, such as thioredoxin reductase, may confer chemical reversibility, which contributes to their oxidative resistance and potential catalytic functions.
April 2017 in “The FASEB journal” This study suggests that selenium deprivation in mice accelerates age-related degeneration but paradoxically promotes longevity, potentially decoupling healthspan from lifespan.
April 2015 in “The FASEB Journal” This study suggests that selenium deficiency accelerates aging-related health deterioration in mice with short telomeres, providing a model for exploring selenium’s role in human aging.
This study found that urinary and serum selenium levels were the most sensitive biomarkers for selenium intake in adult dogs, with serum GPx responding more quickly than whole blood GPx.
October 2014 in “Journal of Nutrition & Food Sciences” This study found that in visceral-obese Korean adults, hair chromium and selenium levels were inversely associated with insulin resistance, while copper levels showed a positive association.
January 2013 in “University Libraries (University of Maryland)” This study suggests that selenium deficiency contributes to aging signs and health deterioration in a mouse model, supporting selenium's role in genome maintenance and protection against oxidative stress.
This article provides an overview of various selenium-based products, their uses in treating conditions from cancer to dandruff, and lists potential adverse effects and interactions, but reports no new results.
In a study on mice, the addition of 100 µM zinc to green papaya extract significantly improved wound healing and hair regrowth compared to other treatments, without causing inflammation.
January 2007 in “Chinese journal of plastic surgery” In this study, researchers observed that sodium selenite may counteract the pro-apoptotic effects of sodium fluoride on human scalp hair follicle cells in vitro.
January 2005 in “The Chinese Journal of Dermatovenereology” In this study, sodium fluoride at certain concentrations increased the MDA levels in cultured human hair follicles, while 0.01 mmol/L sodium selenite reduced this effect at lower fluoride concentrations.
January 2004 in “Chinese Journal of Aesthetic Medicine” This study found that sodium fluoride concentrations inhibited the growth of human hair follicles in vitro, while sodium selenite at a specific concentration mitigated its toxicity.
This review discusses the link between selenium levels in the environment and related diseases in China, reporting no clinical results; the authors highlight the need for clearer geographic risk and remediation strategies.
August 2026 in “International Journal of Nanomedicine” This review discusses the transformation of selenium nanoparticles into multifunctional platforms for skin disease treatment, focusing on engineering principles rather than their intrinsic bioactivity alone, and reports no new clinical results.
September 2025 in “ACS Applied Polymer Materials” This study reported that a composite hydrogel made with Chlorella-derived extracellular polysaccharide–selenium nanoparticles showed strong antibacterial and anti-inflammatory effects in vitro and significantly accelerated wound healing in vivo, offering potential for managing infected wounds and monitoring healing progression.
May 2025 in “Journal of Dermatological Treatment” This study found that a medicated shampoo containing selenium sulfide and salicylic acid effectively reduced symptoms of seborrheic dermatitis in Chinese patients, but females experienced significantly lower rates of good effectiveness and tolerance compared to males.
March 2025 in “Skin Appendage Disorders” In this study, selenium disulfide shampoo was found to reduce dandruff severity and rebalance the scalp microbiome in individuals with all hair types experiencing moderate to severe dandruff, with subjects reporting high satisfaction and good tolerance over a 6-week period.
March 2025 in “Journal of Controlled Release” This study found that a biocomposite microneedle system, which includes selenium nanozyme and hypoxic extracellular vesicles, enhanced hair density and follicle diameter in androgenetic alopecia mice by fighting inflammation, promoting blood vessel growth, reducing reactive oxygen species, and counteracting androgen effects.
September 2024 in “Journal of the American Academy of Dermatology” This introduction highlights that a common challenge with managing dandruff, a mild form of seborrheic dermatitis, is compliance with treatment, and notes that selenium disulfide shampoo is beneficial for this condition.
February 2024 in “Exposure and Health” Selenium supplements may reduce mercury levels in the hair of city dwellers in China.
February 2024 in “Animals” This study found that supplementing pregnant Hanshan white cashmere goats' diets with selenium yeast led to higher birth weights, improved cashmere quality and yield, and enhanced hair follicle development in their offspring, possibly through increased antioxidant capacity.
September 2023 in “Food and chemical toxicology” In this study on Sprague-Dawley rats, 0.60 mg/kg doses of L-Se-methylselenocysteine and sodium selenite were associated with liver toxicity and reduced sperm motility, while Se-enriched peptides showed no observable adverse effects up to 0.60 mg/kg.