May 1990 in “ThinkTech (Texas Tech University)” This review discusses the cytotoxic effects of various selenium compounds on human mammary tumor cells and explores the impact of selenium and magnesium in dietary studies with nude mice, reporting no new clinical results.
September 1980 in “PubMed” This study found that applying a surfactant solution with 2.5% selenium disulfide to the back of guinea pigs significantly increased telogen hair, which may relate to observations of diffuse hair loss in humans under intense exposure conditions.
January 2023 in “Research Square (Research Square)” In this study, CoQ10 and selenium nanoparticles showed potential to alleviate hyperlipidemia and simvastatin-induced side effects in rats, but a triple combination with simvastatin caused intense liver and muscle damage.
12 citations
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December 1962 in “Journal of Investigative Dermatology” July 2026 in “Journal of the American Academy of Dermatology” January 2005 in “Zhonghua xingwei yixue yu naokexue zazhi” This study found that long-term selenium and iodine deficiencies in rats led to growth delays and abnormal neural behavior by the fourth generation.
14 citations
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January 1984 in “Nutrition reports international” October 2009 in “The American Journal of Gastroenterology” This report describes a case where selenium supplementation in excess may have led to toxic liver injury, suggesting that high-dose selenium can cause hepatic necrosis.
May 2014 in “The Journal of Alternative and Complementary Medicine” Higher levels of chromium, selenium, and copper in hair are linked to increased insulin resistance in visceral-obese adults.
This study found that certain concentrations of sodium fluoride accelerated apoptosis in cultured human hair follicles, while sodium selenite could counteract this toxicity in vitro.
21 citations
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April 2009 in “Trace Elements and Electrolytes” This study found that autistic children had significantly lower iron levels and higher selenium levels in their hair compared to healthy peers, with variations observed between autistic boys and girls.
134 citations
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December 2018 in “Dermatology and Therapy” This review discusses the potential role of vitamins and minerals in managing non-scarring alopecia but reports no clinical results; the authors advocate for further controlled trials to explore these relationships.
125 citations
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May 2010 in “Pediatric dermatology” This review presents European guidelines for treating tinea capitis, noting systemic antifungals are essential, with griseofulvin preferred for Microsporum infections and newer antifungals viable for Trichophyton but often costlier.
79 citations
,
January 2017 in “Dermatology practical & conceptual” This article addresses the need to screen for nutrient deficiencies in patients with hair loss but reports no new findings, noting that supplementation without deficiency may not be beneficial and could pose risks.
66 citations
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November 1997 in “Nutrition” This study found that while micronutrient abnormalities are common among patients receiving home parenteral nutrition, serious consequences from these abnormalities are rare.
65 citations
,
August 2016 in “Metabolic brain disease” This study found that children with autism spectrum disorder generally have lower levels of both essential and toxic trace elements in their hair compared to controls.
63 citations
,
May 2017 in “American Journal of Clinical Dermatology” This review found that patients with alopecia areata may have lower levels of vitamin D, zinc, and folate, but conflicting evidence precludes definitive clinical recommendations for micronutrient supplementation.
63 citations
,
March 2000 in “Annals of clinical psychiatry” This article reviews the association between psychopharmaceuticals and medication-induced alopecia, noting that hair regrowth typically occurs after discontinuing or reducing the medication, while mineral supplements' effectiveness remains unclear.
51 citations
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March 1986 in “Acta Dermato Venereologica” This study found no differences in trace element concentrations between Finnish alopecia patients and the normal population, but noted significant serum copper variation among different alopecia subtypes.
47 citations
,
January 2003 in “American Journal of Clinical Dermatology” This article discusses the potential for severe adverse cutaneous drug reactions with mood-stabilizing agents, emphasizing the importance of monitoring and patient communication, but reports no new clinical findings.
31 citations
,
September 2010 in “Current Opinion in Clinical Nutrition & Metabolic Care” This review discusses the lack of specific micronutrient supplementation recommendations for hair loss in patients on long-term parenteral nutrition and reports no new clinical results.
27 citations
,
September 2017 in “Journal of Medicinal Food” In this study, researchers found that a polyphenolic extract from Annurca apples, high in procyanidin B2, increased hair growth, density, and keratin content in healthy subjects after 2 months of use, and stimulated keratin biosynthesis in vitro.
23 citations
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February 2017 in “Journal of dermatology” This meta-analysis suggests that patients with alopecia areata have lower serum levels of zinc and selenium compared to healthy controls, which may be important risk factors for the condition.
23 citations
,
January 2019 in “Journal of wildlife diseases” This study found that a significant number of boreal woodland caribou in NE British Columbia showed symptoms of trace mineral deficiencies and exposure to various pathogens, with substantial winter tick infestations affecting a majority of individuals.
20 citations
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July 1990 in “Pediatrics in Review” This piece explains that 90% to 95% of pediatric alopecia cases are due to four main causes: alopecia areata, telogen effluvium, tinea capitis, and trichotillomania, with diagnosis typically confirmed through careful examination.
20 citations
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January 1990 in “Journal of dermatological treatment” This study found that both ketoconazole 2% shampoo and selenium sulphide are effective for dandruff treatment, but ketoconazole also reduces hair growth.
19 citations
,
January 2019 in “International Journal of Trichology” This consensus paper reviews expert opinions on treating telogen effluvium but reports no new clinical findings.
18 citations
,
January 1977 in “Annals of Nutrition and Metabolism” This article reviews inherited mineral and trace element disturbances and reports no clinical results; it highlights conditions like hypomagnesaemia and acrodermatitis enteropathica linked to impaired nutrient absorption.