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    Did you mean Secondary Intention Healing?
    Glossary Secondary Intention Healing

    wound heals naturally from the bottom up without stitches

    Secondary Intention Healing refers to the process by which a wound heals naturally without surgical closure. Instead of stitching the wound edges together, the wound is left open and heals from the bottom up, through the formation of granulation tissue, contraction, and epithelialization. This method is often used for large, infected, or non-approximable wounds and typically results in a larger scar compared to primary intention healing.

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    Research 30 of 1000+

    1. Never too old to regenerate? Wound induced hair follicle neogenesis after secondary intention healing in a geriatric patient Journal of Tissue Viability · 2018 · 7 citations
    2. Surgical excision of acne keloidalis nuchae with secondary intention healing Clinical and experimental dermatology · 2007 · 24 citations
    3. Potential of the Nano-Encapsulation of Antioxidant Molecules in Wound Healing Applications: An Innovative Strategy to Enhance the Bio-Profile Molecules · 2025 · 6 citations
    4. Beyond Comfortable: A Removable Antibacterial Electroconductive Cellulose Nonwoven Dressing for Accelerated Wound Healing Nano Letters · 2025 · 2 citations
    5. γδ T cells mediate a requisite portion of a wound healing response triggered by cutaneous poxvirus infection bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
    6. Secondary soft tissue revision surgery at skeletal maturity in patients with orofacial clefts 2022
    7. Spatiotemporal secondary hair follicle development in the Lanyu pig (Sus scrofa taivanus): a novel pelage hair follicle model bioRxiv (Cold Spring Harbor Laboratory) · 2026
    8. Necrosis of the donor site after hair restoration with follicular unit extraction (FUE): A case report Journal of Plastic Reconstructive and Aesthetic Surgery · 2011 · 28 citations
    9. Scalp and calvarial reconstruction 2015 · 1 citations
    10. Hidradenitis Suppurativa and Wound Management 2015 · 17 citations
    11. Juri Flap Procedure for the Treatment of Baldness: Two-Year Experience Archives of Otolaryngology-head & Neck Surgery · 1979 · 21 citations
    12. 1455 Cutaneous wounds healed at the cost of overall fitness in the aged Balb/C mouse model Journal of Investigative Dermatology · 2018
    13. Repair of a Complex Forehead Defect Involving the Brow Dermatologic Surgery · 2016 · 3 citations
    14. Aesthetic Considerations in Scalp Reconstruction Facial Plastic Surgery · 2008 · 19 citations
    15. APPLICATION OF ACELLULAR GRAFTS FOR EXTENSIVE SKIN DEFECTS – A REVIEW Bulgarian Portal for Open Science · 2025
    16. Differences in anatomical area-specific wound healing in hidradenitis suppurativa/acne inversa after surgery European Journal of Dermatology · 2021 · 8 citations
    17. Surgical Management of Scarring Alopecia IntechOpen eBooks · 2022
    18. Refractory Folliculitis Decalvans Treatment Success with a Novel Surgical Excision Approach Using Guarded High-Tension Sutures Clinical, cosmetic and investigational dermatology · 2023
    19. Hair cell loss – cause or consequence of hearing loss? Frontiers in Cell and Developmental Biology · 2026
    20. Hyaluronic Acid Hydrogel Incorporating Dexpanthenol-Engineered Extracellular Vesicles for Accelerated Wound Closure and Mitigated Secondary Infection Risk Pharmaceutics · 2026
    21. Secondary milia following bullous erysipelas. PubMed · 1994 · 4 citations
    22. 1,25-dihydroxyvitamin D resistance, rickets, and alopecia The American Journal of Medicine · 1984 · 110 citations
    23. Individual Human Hair Keratin Rapidly Extracted Through the Advanced Oxidation Process and Their Hemostatic and Wound Healing Evaluations ACS Applied Polymer Materials · 2023
    24. Live imaging of Smad2/3 signaling in mouse skin wound healing Wound repair and regeneration · 2007 · 12 citations
    25. Antibacterial and wound healing stimulant nanofibrous dressing consisting of soluplus and soy protein isolate loaded with mupirocin Scientific Reports · 2024 · 38 citations
    26. γδ T Cells Mediate a Requisite Portion of a Wound Healing Response Triggered by Cutaneous Poxvirus Infection Viruses · 2024 · 3 citations
    27. Diffuse Hair Loss in Secondary Syphilis in HIV Positive Man: Case Report Acta Facultatis Medicae Naissensis · 2012 · 2 citations
    28. Corneal punctate epitheliopathy secondary to trichiasis following eyelash transplantation Canadian journal of ophthalmology · 2012
    29. Bioactive Small Molecule Enhances Skin Burn Wound Healing and Hair Follicle Regeneration by Activating PI3K/AKT Signaling Pathway: A Preclinical Evaluation in Animal Model Journal of Biomedical Nanotechnology · 2022
    30. Advanced polymer hydrogels that promote diabetic ulcer healing: mechanisms, classifications, and medical applications Biomaterials Research · 2023 · 6 citations