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    Glossary Sebocyte Differentiation

    process where gland cells mature to produce skin oil

    Sebocyte differentiation is the process by which immature cells in the sebaceous glands mature into sebocytes, the cells responsible for producing and secreting sebum, an oily substance that lubricates and protects the skin and hair. This process is crucial for maintaining healthy skin and hair, and disruptions in sebocyte differentiation can lead to skin conditions like acne or seborrheic dermatitis.

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    Research 30 of 954

    1. C/EBPα and C/EBPβ Are Required for Sebocyte Differentiation and Stratified Squamous Differentiation in Adult Mouse Skin PloS one · 2010 · 48 citations
    2. Loss of keratin 10 is accompanied by increased sebocyte proliferation and differentiation European journal of cell biology · 2004 · 36 citations
    3. Androgens induce sebaceous differentiation in sebocyte cells expressing a stable functional androgen receptor 2015 · 31 citations
    4. Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin Genes & Development · 2001 · 555 citations
    5. c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny Current Biology · 2001 · 338 citations
    6. CLK1 and its Effects on Skin Stem Cell Differentiation Digital WPI · 2010 · 1 citations
    7. Differentiation of the sebaceous gland Dermato-Endocrinology · 2009 · 60 citations
    8. The role of cell–cell and cell–matrix junctional complexes in sebaceous gland homeostasis and differentiation Cell Communication and Signaling · 2024 · 6 citations
    9. Scaling dermatosis in three dogs associated with abnormal sebaceous gland differentiation Veterinary dermatology · 2013 · 2 citations
    10. Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by Myc-Induced Differentiation PLoS ONE · 2007 · 98 citations
    11. Sex hormones and acne Clinics in dermatology · 2016 · 76 citations
    12. BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions Stem cell reports · 2014 · 50 citations
    13. Functions of peroxisome proliferator‐activated receptors (PPAR) in skin homeostasis Lipids · 2004 · 46 citations
    14. TGFβ signaling regulates lipogenesis in human sebaceous glands cells BMC Dermatology · 2013 · 44 citations
    15. Role of insulin resistance and diet in acne Indian Journal of Dermatology, Venereology and Leprology · 2013 · 39 citations
    16. PPAR‐γ signalling as a key mediator of human hair follicle physiology and pathology Experimental Dermatology · 2019 · 24 citations
    17. Contributions of peroxisome proliferator-activated receptor β/δ to skin health and disease BioMolecular Concepts · 2012 · 12 citations
    18. 284 Backhousia citriodora leaf extract: A new active solution to control hyper-seborrhea for multi-ethnic skins Journal of Investigative Dermatology · 2017 · 1 citations
    19. Human skin stem cells and the ageing process Experimental gerontology · 2008 · 143 citations
    20. Structural changes in hair follicles and sebaceous glands of hairless mice following exposure to sulfur mustard Experimental and Molecular Pathology · 2014 · 14 citations
    21. Development and homeostasis of the sebaceous gland Seminars in Cell & Developmental Biology · 2012 · 107 citations
    22. Beyond acne: Current aspects of sebaceous gland biology and function Reviews in Endocrine and Metabolic Disorders · 2016 · 97 citations
    23. Developmental signals in skin morphogenesis Experimental Dermatology · 2004
    24. Scalp Sebaceous Physiology Springer eBooks · 2017
    25. 110 Transglutaminase 2 is a potential regulator of sebocyte maturation 2017
    26. Lipid droplets and associated proteins in sebocytes Experimental Cell Research · 2015 · 24 citations
    27. 260 Establishment and characterization of human sebocytic progenitor cells that can differentiate into functional sebocytes Journal of Investigative Dermatology · 2017
    28. Effects of α-Synuclein on the Lipid Phenotype of SZ95 Human Sebocytes: A Preliminary Study in the Context of Parkinson’s Disease Cells · 2026
    29. 892 Behavior of the two circulating androgens testosterone and DHEA and their main intracellular metabolites in an androgen-sensitive sebocyte cell line Journal of Investigative Dermatology · 2019
    30. Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment Development · 2003 · 182 citations