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GlossarySZ95 Sebocytes

human sebaceous gland cells used in skin research

SZ95 Sebocytes are a type of human sebaceous gland cell line used in scientific research. These cells are derived from sebaceous glands, which are responsible for producing sebum, an oily substance that helps keep the skin and hair moisturized. Researchers use SZ95 Sebocytes to study skin conditions, such as acne and alopecia, and to test the effects of various treatments on sebaceous gland function.

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research Inhibition of 5α-Reductase Activity in SZ95 Sebocytes and HaCaT Keratinocytes In Vitro

24 citations , February 2007 in “Hormone and metabolic research”

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

research Inhibition of Lipogenesis and Sebum Secretion for Lotus Corniculatus Seed Extract In Vitro and In Vivo

1 citations , November 2022 in “International Journal of Cosmetic Science”

Lotus corniculatus seed extract reduces oily skin by decreasing sebum production.

research Expression of Dermcidin in Sebocytes Supports a Role for Sebum in the Constitutive Innate Defense of Human Skin

25 citations , November 2015 in “Journal of Dermatological Science”

Sebum helps protect human skin from microbes.

research Endocannabinoid-Like Molecule Oleoylethanolamide Promotes Sebaceous Lipid Synthesis

1 citations , April 2018 in “Journal of Investigative Dermatology”

Oleoylethanolamide (OEA) safely boosts fat production in skin cells and may help treat dry skin and reduce inflammation.

Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 Sebocytes

research Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 Sebocytes

29 citations , February 2007 in “Hormone and metabolic research”

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

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