63 citations,
March 2001 in “Fertility and Sterility” Diane 35 plus finasteride is more effective for treating hirsutism.
59 citations,
June 2022 in “Frontiers in medicine” There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
59 citations,
August 2007 in “Clinical Endocrinology” The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.
57 citations,
November 2017 in “Nature Communications” Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.
57 citations,
February 2007 in “International Journal of Cancer” A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.
57 citations,
July 2005 in “Genetics” Key genes are crucial for Drosophila wing development and could be insecticide targets.
56 citations,
April 2003 in “Fertility and Sterility” All three treatments reduce hirsutism, but spironolactone works best long-term.
54 citations,
January 2018 in “Scientific reports” Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.
52 citations,
February 2006 in “Current pharmaceutical design” 5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.
50 citations,
September 2016 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.
50 citations,
December 2010 in “Bjog: An International Journal Of Obstetrics And Gynaecology” South Asian women with PCOS experience more psychological distress and have a poorer quality of life, especially in social relationships, with hirsutism affecting them more than obesity.
49 citations,
November 2019 in “Egyptian Journal of Medical Human Genetics” Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.
49 citations,
March 2009 in “Archives of Gynecology and Obstetrics” Older age, higher BMI, and family history of diabetes increase the risk of gestational diabetes in pregnant women.
49 citations,
February 2008 in “Stem Cells” Wnt10b helps blood stem cells grow after injury.
48 citations,
July 2018 in “Journal of The American Academy of Dermatology” Spironolactone helps reduce pain and lesions in hidradenitis suppurativa patients, and lower doses are also effective.
48 citations,
February 2014 in “Fertility and Sterility” Women with PCOS often have hair loss, which is linked to acne or excess body hair but not to worse hormone or metabolic issues.
48 citations,
July 2009 in “The Journal of Sexual Medicine” DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.
47 citations,
June 2011 in “Movement Disorders” The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.
47 citations,
March 2004 in “European journal of endocrinology” Spironolactone plus finasteride reduces hirsutism more effectively.
47 citations,
August 2000 in “Endocrine Reviews” The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
46 citations,
August 2019 in “Journal of the European Academy of Dermatology and Venereology” People with hair loss conditions experience more anxiety, depression, and a lower quality of life than those without these conditions.
46 citations,
November 2011 in “Forest Ecology and Management” Understanding the fruiting patterns of Ficus trees can improve forest restoration by ensuring pollinators survive and biodiversity is supported.
46 citations,
September 2011 in “Movement Disorders” Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.
46 citations,
January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
42 citations,
November 2019 in “Frontiers in Endocrinology” The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.
42 citations,
July 2015 in “Journal of The American Academy of Dermatology” The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.
42 citations,
December 2014 in “Clinical, cosmetic and investigational dermatology” Nonablative radiofrequency treatments, especially microneedle and fractional types, can improve acne scars by 25%–75% after 3-4 sessions, with full results in 3 months and some side effects.
41 citations,
April 2016 in “Journal of experimental botany” RACB in barley is crucial for cell polarity and nucleus positioning, aiding fungal infection.
40 citations,
December 1980 in “The Journal of Dermatologic Surgery and Oncology” An improved scalp reduction technique reduces the need for hair grafts and has minimal complications.
40 citations,
September 2017 in “F1000Research” Oral minoxidil effectively reduces hair shedding in women with CTE, with no major side effects.