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While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Some medicinal plants can help heal wounds and may lead to new treatments.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Early hair loss may indicate risk of insulin resistance.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Ginseng is possibly safe but its effectiveness is unclear due to poor quality studies and mixed results.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Smart biomaterials that guide tissue repair are key for future medical treatments.

New treatments for male hypogonadism are effective and should be personalized.

Toxic Shock Syndrome progresses quickly, often involves multiple organs, and is linked to Staphylococcus aureus toxins, with treatment options available but diagnostic challenges remaining.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Different types of facial fat affect aging and treatment outcomes; more research is needed to enhance anti-aging procedures.