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    Glossary S100A8

    protein involved in immune response and inflammation

    S100A8 is a protein that plays a role in the body's immune response and inflammation. It is part of the S100 family of proteins and is often found in high levels in conditions involving chronic inflammation, such as certain types of alopecia (hair loss) and other inflammatory diseases.

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    Research 30 of 447

    1. 322 Upregulation of SERPINB3/B4 and S100A7-9 in hidradenitis suppurativa/acne inversa 2019
    2. Cross-species comparative spatial transcriptomics of hair follicle-T cell interactions identifies conserved drivers of cutaneous lupus erythematosus skin disease and associated hair loss Nature Communications · 2026
    3. 0034 Cross-species insights into hair follicle-T cell interactions in discoid lupus erythematosus: A comparison of human, canine and mouse models using spatial transcriptomics Journal of Investigative Dermatology · 2025
    4. Comparative spatial transcriptomics of hair follicle-T cell interactions in mouse, dog and human reveals conserved drivers of primary cicatricial alopecia bioRxiv (Cold Spring Harbor Laboratory) · 2025
    5. 1322 Molecular profiling of frontal fibrosing alopecia (FFA) reveals TH1 and JAK-STAT up-regulation with no suppression of hair keratins Journal of Investigative Dermatology · 2018 · 2 citations
    6. A functional role of S100A4/non-muscle myosin IIA axis for pro-tumorigenic vascular functions in glioblastoma Cell Communication and Signaling · 2022 · 9 citations
    7. A Functional Role of S100A4/Non-Muscle Myosin IIA Axis for Pro-Tumorigenic Vascular Functions in Glioblastoma Research Square (Research Square) · 2021
    8. Pathogenic variants affecting peptidyl arginine deiminase 3 and its major substrates underlie central centrifugal cicatricial alopecia Journal of Investigative Dermatology · 2025
    9. Pathogenic variants affecting peptidyl arginine deiminase 3 and its major substrates underlie central centrifugal cicatricial alopecia. PubMed · 2025
    10. 481 Pathogenic variants affecting peptidyl arginine deiminase 3 and its major substrates underlie central centrifugal cicatricial alopecia Journal of Investigative Dermatology · 2024
    11. 3D-SeboSkin Model for Human ex vivo Studies of Hidradenitis Suppurativa/Acne Inversa Dermatology · 2021 · 4 citations
    12. Gene Expression of Mouse S100A3, a Cysteine-Rich Calcium-Binding Protein, in Developing Hair Follicle 1998 · 40 citations
    13. Hot water extract of oriental melon leaf promotes hair growth and prolongs anagen hair cycle: In vivo and in vitro evaluation Food Science and Biotechnology · 2016 · 3 citations
    14. Hair growth promoting effect of essence manufactured with products fermented by Lactobacillus rhamnosus and Backryeoncho (Opuntia ficus-indica var. sarboten) fruits in mice Food Science and Biotechnology · 2012 · 1 citations
    15. Significance of the S100A4 Protein in Psoriasis Journal of Investigative Dermatology · 2009 · 45 citations
    16. Increased expression of psoriasin (S100A7) and interleukin 17 (IL-17) in lesional skin in lichen planopilaris Advances in Dermatology and Allergology · 2024 · 2 citations
    17. Depletion of S100A4+ stromal cells results in abnormal nipple development and nursing failure 2026
    18. Blockade of S100A3 activity inhibits murine hair growth Genetics and Molecular Research · 2015 · 1 citations
    19. Exosome‐derived long non‐coding RNA AC010789.1 modified by FTO and hnRNPA2B1 accelerates growth of hair follicle stem cells against androgen alopecia by activating S100A8/Wnt/β‐catenin signalling Clinical and Translational Medicine · 2025
    20. S100A6: molecular function and biomarker role Biomarker Research · 2023 · 50 citations
    21. Selective Expression of Calcium-Binding Proteins S100A8 and S100A9 at Distinct Sites of Hair Follicles Journal of Investigative Dermatology · 2001 · 22 citations
    22. S100A6 Protein—Expression and Function in Norm and Pathology International Journal of Molecular Sciences · 2023 · 21 citations
    23. S100A8 induces cyclophosphamide-induced alopecia via NCF2/NOX2-mediated ferroptosis Free Radical Biology and Medicine · 2025 · 2 citations
    24. Molecular Regulation of Secondary Hair Follicle Stem Cell by S100a4 in Cashmere Goat International Journal of Molecular Sciences · 2026
    25. Invasion and increased expression of S100A4 and CYR61 in mesenchymal transformed breast cancer cells is downregulated by GnRH International Journal of Oncology · 2016 · 21 citations
    26. Specific Citrullination Causes Assembly of a Globular S100A3 Homotetramer 2007 · 62 citations
    27. Ultrastructural Localization of S100A3, a Cysteine-rich, Calcium Binding Protein, in Human Scalp Hair Shafts Revealed by Rapid-freezing Immunocytochemistry Journal of Histochemistry & Cytochemistry · 1999 · 40 citations
    28. Prenatal Exposure to Delta-9-tetrahydrocannabinol (THC) Alters the Expression of miR-122-5p and Its Target Igf1r in the Adult Rat Ovary International Journal of Molecular Sciences · 2022 · 9 citations
    29. S100A4/Nonmuscle Myosin IIA/p53 Axis Contributes to Aggressive Features in Ovarian High-Grade Serous Carcinoma American Journal Of Pathology · 2020 · 32 citations
    30. Construction of regulatory network for alopecia areata progression and identification of immune monitoring genes based on multiple machine-learning algorithms Precision clinical medicine · 2023 · 3 citations