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This review explores the potential of using genetically-manipulated stem cells as both therapeutic agents and gene delivery vehicles for enhanced wound regeneration, but it reports no new clinical results.

This study found that non-vitiliginous melanocyte stem cells from vitiligo patients were unaffected by the disease and could effectively differentiate into melanin-producing melanocytes, suggesting their potential for use in cellular therapy for vitiligo repigmentation.

Harris et al. describe a new mouse model for vitiligo, where interfollicular melanocytes are retained and melanocyte-targeting immune responses are simulated, aiding the development of immunomodulatory therapies.

This review explores the mechanisms of skin repigmentation and therapeutic strategies for pigmentation disorders following burn injuries, but it presents no new clinical results.

This review summarizes the historical and evolving treatments for vitiligo, highlighting that combining medical and surgical approaches may enhance repigmentation outcomes, though more research and new protocols are needed.

This editorial reviews how photobiomodulation therapy might effectively treat both hyperpigmentation and depigmentation skin disorders, but reports no new clinical results.

This review discusses segmental vitiligo as part of the vitiligo clinical spectrum and highlights its role as a model for studying repigmentation, but reports no new clinical results.

This study reports that hair follicle neural crest stem cells in mice can be differentiated into melanocytes, potentially aiding repigmentation in vitiligo-affected areas.

This study found that the expression of CK 15 and CK 19 in vitiligo patients undergoing phototherapy was correlated with improved repigmentation, suggesting their potential as markers for stem cell stimulation.

This pilot study employed in-vivo multiphoton microscopy to visualize pigment-producing melanocytes in vitiligo patients, aiming to enhance understanding of treatment impacts and potentially improve transplantation therapies.

This chapter reviews surgical management techniques for leukotrichia in vitiligo and presents no new clinical findings; it highlights various grafting and epilation methods.

The researchers observed that vitiligo-affected skin shows a selective depletion of NTRK2+ melanocyte subpopulations with progenitor features, which may contribute to poor treatment responses.

In this study, the combination of topical minoxidil 5% and betamethasone valerate 0.1% achieved slightly higher depigmentation in vitiligo of hair-bearing areas but did not show significant improvement over betamethasone valerate alone.

In this study, researchers found that punch grafting was more effective than follicular hair transplantation for treating stable vitiligo; however, follicular hair transplantation was found to be cosmetically preferable for exposed areas like the face due to fewer side effects.

This case highlights the importance of considering syphilis testing for patients with unusual symptoms like hair loss and hypopigmentation, emphasizing the diagnostic and management challenges in resource-limited settings.

In this veterinary study, uveodermatological syndrome in dogs was reported to cause skin depigmentation, alopecia, and eye issues such as granulomatous panuveitis, which leads to complications like cataracts and glaucoma; while immunosuppressive therapy often helps, recurrence and treatment side effects challenging therapeutic management.

In this study, NB-UVB therapy significantly increased Wnt1 and β-catenin expression in hair follicles, which may play a role in vitiligo perifollicular repigmentation.

This narrative review proposes the concept of "repigmentation competence" for vitiligo lesions, suggesting that therapy responses are influenced by lesion-specific biological factors related to immune, regenerative, regulatory, and microenvironmental processes, and highlights the emerging role of combination therapies targeting these pathways.

This study found that low-level laser therapy combined with NB-UVB therapy led to improvement in re-pigmentation for many stable vitiligo patients, with minimal and transient side effects.

This study found that combining follicular unit extraction with topical calcipotriol betamethasone dipropionate showed the best repigmentation results in treating stable nonsegmental vitiligo.

This study developed and tested a novel microneedle treatment loaded with nanoparticles for vitiligo, leading to enhanced skin repigmentation by targeting immune cells and reducing oxidative stress in a minimally invasive manner.

This review reports the first known case of hair repigmentation associated with lamivudine use and examines mechanisms related to drug-induced hair repigmentation, suggesting potential therapeutic strategies for reversing hair graying.

This review discusses the evidence and literature on phototherapy for vitiligo but reports no novel clinical findings, highlighting the treatment's reliance on melanocyte reservoirs for repigmentation.

In this study, an 18-year-old female with vitiligo underwent Pracchana Karma and Ayurvedic treatments, resulting in progressive skin re-pigmentation and improved quality of life without adverse effects.

This retrospective study found that intralesional betamethasone injections led to significant repigmentation in scalp vitiligo patients without leukotrichia, suggesting it as an effective treatment option.

This case report describes a patient who experienced rapid hair depigmentation after starting pazopanib for metastatic renal cell carcinoma, which may suggest therapy success despite being distressing.

In this report, a 77-year-old woman treated for essential thrombocytosis with low-dose hydroxyurea experienced an unexpected change in hair color from gray to dark brown after 20 weeks, highlighting a potential aesthetic side effect of the drug, in addition to therapeutic effects.

In this study, researchers treated 20 patients with lip vitiligo using manual needling followed by 88% phenol application and found that 65% of patients achieved more than 75% repigmentation within three months, indicating this combination as an effective treatment option.

This review highlights the varied therapeutic applications of punch-based techniques in dermatologic surgery, noting consistent evidence for follicular unit extraction in androgenetic alopecia, but more mixed results for scar treatment, vitiligo, and chronic wounds, warranting further standardized research.

This case report describes promising results in treating poliosis circumscripta with exosomes and fractional picosecond laser, showing significant hair regrowth and repigmentation, though spontaneous repigmentation cannot be ruled out.