This scoping review reports that microneedling appears to be beneficial as an adjunctive therapy for cutaneous manifestations of autoimmune diseases like alopecia areata and vitiligo, improving outcomes when paired with other treatments, though evidence is limited and further research is needed.
2 citations
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May 2025 in “IntechOpen eBooks” This article highlights that early and high-dose corticosteroid therapy, along with immunosuppressive agents, is crucial for managing Vogt-Koyanagi-Harada disease, and emerging biological therapies may benefit refractory cases.
December 2025 in “Cosmoderma” This study reviewed evidence suggesting that systemic corticosteroids, particularly in pulse regimens like dexamethasone and betamethasone oral mini-pulse, effectively slow vitiligo progression and support repigmentation, while offering a favorable safety profile compared to continuous therapy.
December 2024 in “Journal of Clinical Medicine of Kazakhstan” This review highlights the potential of combining immune regulation, phototherapy, and dietary strategies for effective vitiligo treatment, but emphasizes that more research is needed.
45 citations
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January 2007 in “Journal of Clinical Oncology” This case report identifies hand-foot and stump syndrome as a potential side effect of sorafenib therapy in a 47-year-old man with a leg amputation.
July 2026 in “Frontiers in Pediatrics” In this case study, an 11-year-old girl with severe alopecia areata experienced complete hair regrowth and unexpected white-to-black hair repigmentation after switching from baricitinib to ritlecitinib, suggesting that prolonged Janus kinase inhibition may aid both hair and pigment restoration in severe pediatric cases.
May 2024 in “Rossijskaâ oftalʹmologiâ onlajn” In this case report, a 17-year-old Korean female with Vogt–Koyanagi–Harada syndrome showed positive improvement in her symptoms following systemic glucocorticosteroid pulse therapy, highlighting the rarity and importance of early disease detection.
2 citations
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July 2022 in “Pediatric dermatology” This case report highlights that a restrictive rice milk diet in a young child led to kwashiorkor with severe malnutrition, skin changes, and developmental regression, which improved with a protein-rich therapeutic diet.
February 2025 in “Cosmetics” This narrative review explored how blue light therapy may offer therapeutic benefits for various skin disorders by affecting microbial activity and immune responses, promoting hair growth, and aiding skin rejuvenation and healing.
February 2024 in “Journal of Cosmetic Dermatology” White hair patch repigmented and hair regrew in a balding patient after treatment with exosomes and laser.
August 2026 in “Frontiers in Medicine” This review discusses the potential applications of JAK inhibitors in various dermatological conditions beyond atopic dermatitis, emphasizing gaps in evidence and therapeutic opportunities in the context of Chinese clinical practice, but reports no new clinical results.
January 2025 in “Frontiers in Medicine” This study reviews the role of hair follicles in the development, symptoms, and treatment options for vitiligo and alopecia areata, aiming to enhance understanding of their involvement in these autoimmune conditions and explore potential therapies.
21 citations
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January 2005 in “Pediatric Dermatology” An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.
March 2026 in “Clinical Cosmetic and Investigational Dermatology” In this case report, a 30-year-old woman with myasthenia gravis developed vitiligo and alopecia universalis during long-term rituximab therapy. Discontinuation of rituximab and initiation of oral baricitinib led to improvement in skin conditions, underscoring potential immune-related skin effects from rituximab.
March 2026 in “SHILAP Revista de lepidopterología” In this case report, a 30-year-old woman with myasthenia gravis developed vitiligo and alopecia universalis during long-term rituximab therapy, suggesting a rare association between the drug and these immune-mediated skin conditions, highlighting the potential benefit of early intervention with baricitinib.
December 2021 in “Figshare” This review discusses recent advancements in targeted therapies for vitiligo, including JAK inhibitors and mesenchymal stem cells, and highlights the need for further research.
14 citations
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February 2023 in “Frontiers in immunology” This review discusses the range of cutaneous immune-related adverse events induced by immune checkpoint inhibitors and the proposed mechanisms underlying these skin reactions, but reports no new clinical results.
5 citations
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January 2018 in “Annals of Dermatology” A 308 nm excimer laser successfully treated a boy with a rare skin condition after about a year of weekly sessions.
This study developed a silk fibroin/poly(vinyl alcohol) microneedle loaded with α-aminoxyacetate and HfO2 nanoparticles for vitiligo treatment, which protected against ROS damage and modulated immune responses, leading to improved melanogenesis and skin repigmentation.
December 2011 in “InTech eBooks” This review discusses the potential role of systemic corticosteroids in the treatment of progressive vitiligo, but reports no new clinical results and suggests further research is needed.
July 2026 in “International Journal of Molecular Sciences” This review highlights that a comprehensive approach combining pharmacological, immunomodulatory, and regenerative interventions, including phototherapy enhanced with topical treatments and JAK inhibitors, appears effective and promising in the management of vitiligo by addressing its autoimmune and melanocyte-loss aspects.
78 citations
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August 2014 in “Anais Brasileiros de Dermatologia” This article discusses a new global consensus on the classification of vitiligo, describing histopathological findings and outlining treatment strategies, but reports no new clinical results.
24 citations
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October 2022 in “Cell Regeneration” This study describes a new mouse model for vitiligo that mimics key clinical features such as skin depigmentation and CD8 + T cell infiltration, providing a useful tool for in-depth research and drug discovery.
12 citations
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May 2023 in “EMBO reports” In this study with organ-cultured human scalp hair follicles, high mTORC1 activity correlated with gray/white hair and reduced pigmentation, while inhibiting mTORC1 with rapamycin increased hair growth and pigmentation, suggesting mTORC1 inhibition could be a strategy for treating hair depigmentation and loss.
8 citations
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January 2017 in “Korean Journal of Physiology and Pharmacology” This study found that pimecrolimus enhances melanin synthesis and promotes melanocyte migration, possibly by increasing MITF protein expression, which may explain its effectiveness in repigmenting vitiligo.
6 citations
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March 2009 in “Pigment Cell & Melanoma Research” This study suggests that a purified sphingolipid fraction can activate melanocyte stem cells via p38 signalling, potentially offering a non-UV-based treatment for vitiligo, though additional validation is needed.
3 citations
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October 2010 in “Dermatologic Surgery” The new surgical technique for vitiligo is effective, safe, and cost-efficient.
August 2023 in “Skin Research and Technology” This study found that platelet-rich plasma is effective and safe for treating chronic wounds, particularly diabetic and venous ulcers, and vitiligo, without increasing the risk of infection.
This article discusses the organizational aspects of the II National Academic Congress of Dermatology in Brazil and reports no new research findings.
January 2019 in “Springer eBooks” Combination therapies might work better for some vitiligo patients, but results vary.