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    Research 451–480 of 1000+

    1. 5-α-Reductase inhibitors for prostate cancer chemoprevention: an updated Cochrane systematic review BJUI · 2010 · 44 citations
    2. Testosterone 5.ALPHA.-Reductase Inhibitory Active Constituents of Piper nigrum Leaf Biological & pharmaceutical bulletin · 2007 · 44 citations
    3. 5-α-Reductase type 2 deficiency: is there a genotype-phenotype correlation? A review Hormones · 2018 · 39 citations
    4. Reduced levels of 5-α reductase 2 in adult prostate tissue and implications for BPH therapy 2011 · 39 citations
    5. 5-Alpha reductase deficiency Current Opinion in Endocrinology, Diabetes and Obesity · 2014 · 38 citations
    6. Anti-androgenic and Hair Growth Promoting Activities of Lygodii Spora (Spore of Lygodium japonicum) I. Active Constituents Inhibiting Testosterone 5.ALPHA.-Reductase. Biological & Pharmaceutical Bulletin · 2002 · 38 citations
    7. Five-alpha-reductase Inhibitors for prostate cancer prevention. The Cochrane library · 2008 · 37 citations
    8. The long-term effect of specific type II 5alpha-reductase inhibition with finasteride on bone mineral density in men: results of a 4-year placebo controlled trial. PubMed · 2002 · 37 citations
    9. 5‐alpha‐reductase inhibitors are associated with reduced frequency of COVID‐19 symptoms in males with androgenetic alopecia Journal of The European Academy of Dermatology and Venereology · 2020 · 36 citations
    10. A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome Urology · 2018 · 35 citations
    11. Side Effects of 5‐Alpha Reductase Inhibitors: A Comprehensive Review Sexual medicine reviews · 2013 · 35 citations
    12. Sex dependent influence of a functional polymorphism in steroid 5‐α‐reductase type 2 (<i>SRD5A2</i>) on post‐traumatic stress symptoms American Journal of Medical Genetics Part B Neuropsychiatric Genetics · 2013 · 35 citations
    13. Inhibitory activities of Puerariae Flos against testosterone 5α-reductase and its hair growth promotion activities Journal of Natural Medicines · 2011 · 34 citations
    14. Azasteroids as inhibitors of testosterone 5α-reductase in mammalian skin 1993 · 34 citations
    15. Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque. The Journal of Clinical Endocrinology and Metabolism · 1992 · 34 citations
    16. Investigation of the Plausibility of 5-Alpha-Reductase Inhibitor Syndrome Skin appendage disorders · 2016 · 33 citations
    17. Clinical and hormonal effects of the 5 alpha-reductase inhibitor finasteride in idiopathic hirsutism. The Journal of Clinical Endocrinology and Metabolism · 1994 · 33 citations
    18. Adverse Effects and Safety of 5-alpha Reductase Inhibitors (Finasteride, Dutasteride): A Systematic Review. PubMed · 2016 · 32 citations
    19. Male Breast Cancer and 5α-Reductase Inhibitors Finasteride and Dutasteride The Journal of Urology · 2013 · 32 citations
    20. Finasteride, a Type 2 5α-reductase inhibitor, in the treatment of men with androgenetic alopecia Expert Opinion on Investigational Drugs · 1999 · 32 citations
    21. The Aldo-Keto Reductase AKR1B10 Is Up-Regulated in Keloid Epidermis, Implicating Retinoic Acid Pathway Dysregulation in the Pathogenesis of Keloid Disease Journal of Investigative Dermatology · 2016 · 31 citations
    22. Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride Nature Communications · 2020 · 30 citations
    23. Risk of erectile dysfunction associated with use of 5-α reductase inhibitors for benign prostatic hyperplasia or alopecia: population based studies using the Clinical Practice Research Datalink BMJ · 2016 · 30 citations
    24. Differential expression of steroid 5α-reductase isozymes and association with disease severity and angiogenic genes predict their biological role in prostate cancer Endocrine Related Cancer · 2010 · 30 citations
    25. Effect of finasteride, a 5 alpha-reductase inhibitor, on serum gonadotropins in normal men. The Journal of Clinical Endocrinology and Metabolism · 1992 · 30 citations
    26. Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study BMJ. British medical journal · 2019 · 29 citations
    27. Incomplete Recovery of Erectile Function in Rat after Discontinuation of Dual 5‐Alpha Reductase Inhibitor Therapy The Journal of Sexual Medicine · 2012 · 29 citations
    28. In Vivo Time-Dependent Inhibition of Human Steroid 5a-Reductase by Finasteride Journal of Pharmaceutical Sciences · 1996 · 29 citations
    29. Benzo[<i>c</i>]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1 Journal of Medicinal Chemistry · 2000 · 28 citations
    30. Biphasic Regulation of HMG-CoA Reductase Expression and Activity during Wound Healing and Its Functional Role in the Control of Keratinocyte Angiogenic and Proliferative Responses Journal of Biological Chemistry · 2008 · 27 citations