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    Research 481–510 of 1000+

    1. Sexual dimorphism of growth plate prehypertrophic and hypertrophic chondrocytes in response to testosterone requires metabolism to dihydrotestosterone (DHT) by steroid 5‐alpha reductase type 1 Journal of Cellular Biochemistry · 2005 · 27 citations
    2. Pharmacogenetic analysis of human steroid 5α reductase type II: comparison of finasteride and dutasteride Journal of Molecular Endocrinology · 2005 · 26 citations
    3. A population‐based nested case–control study: the use of 5‐alpha‐reductase inhibitors and the increased risk of osteoporosis diagnosis in patients with benign prostate hyperplasia Clinical endocrinology · 2014 · 22 citations
    4. Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone. Biochemical Pharmacology · 2001 · 22 citations
    5. Effects of finasteride, a 5 alpha-reductase inhibitor, on circulating androgens and gonadotropin secretion in hirsute women. The Journal of Clinical Endocrinology and Metabolism · 1994 · 22 citations
    6. Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates General and Comparative Endocrinology · 2020 · 21 citations
    7. 5‐alpha‐reductase inhibitor treatment for frontal fibrosing alopecia: an evidence‐based treatment update 2018 · 21 citations
    8. Sexual side effects of 5-α-reductase inhibitors finasteride and dutasteride: A comprehensive review Dermatology Online Journal · 2017 · 21 citations
    9. Abietic Acid from Resina Pini of Pinus Species as a Testosterone 5.ALPHA.-Reductase Inhibitor JOURNAL OF HEALTH SCIENCE · 2010 · 21 citations
    10. Bladder Cancer Survival of Men Receiving 5α-Reductase Inhibitors The Journal of Urology · 2018 · 20 citations
    11. Synthesis of phenanthridin-3-one derivatives: Non-steroidal inhibitors of steroid 5-α-reductase Tetrahedron Letters · 1995 · 20 citations
    12. 5‐Alpha reductase inhibitors in androgenetic alopecia: Shifting paradigms, current concepts, comparative efficacy, and safety Dermatologic Therapy · 2020 · 19 citations
    13. Efficacy and safety of 5 alpha-reductase inhibitor monotherapy in patients with benign prostatic hyperplasia: A meta-analysis PLOS ONE · 2018 · 19 citations
    14. Safety and Tolerability of the Dual 5-Alpha Reductase Inhibitor Dutasteride in the Treatment of Androgenetic Alopecia Annals of Dermatology · 2016 · 19 citations
    15. The risk of dementia with the use of 5 alpha reductase inhibitors Journal of the neurological sciences · 2017 · 18 citations
    16. Selected variants of the steroid-5-alpha-reductase isoforms SRD5A1 and SRD5A2 and the sex steroid hormone receptors ESR1, ESR2 and PGR: No association with female pattern hair loss identified Experimental Dermatology · 2012 · 18 citations
    17. Exposure of Xenopus laevis tadpoles to finasteride, an inhibitor of 5-α reductase activity, impairs spermatogenesis and alters hypophyseal feedback mechanisms Journal of Molecular Endocrinology · 2009 · 18 citations
    18. Geranylated Coumarins From Thai Medicinal Plant Mammea siamensis With Testosterone 5α-Reductase Inhibitory Activity Frontiers in Chemistry · 2020 · 17 citations
    19. Persistent Erectile Dysfunction after Discontinuation of 5-Alpha Reductase Inhibitor Therapy in Rats Depending on the Duration of Treatment The World Journal of Men s Health · 2018 · 17 citations
    20. Saturable Binding of Finasteride to Steroid 5α-reductase as Determinant of Nonlinear Pharmacokinetics Drug Metabolism and Pharmacokinetics · 2010 · 16 citations
    21. The 5-alpha reductase inhibitor finasteride reduces dyskinesia in a rat model of Parkinson’s disease Experimental Neurology · 2017 · 15 citations
    22. A new label-free screen for steroid 5α-reductase inhibitors using LC-MS Steroids · 2016 · 15 citations
    23. 5-Alpha-Reductase Inhibitors and Combination Therapy Urologic Clinics of North America · 2016 · 15 citations
    24. Role of 5 alpha-reductase inhibitors in the management of prostate cancer Clinical interventions in aging · 2006 · 15 citations
    25. Analysis of genetic polymorphisms of steroid 5α-reductase type 1 and 2 genes in Korean men with androgenetic alopecia Journal of Dermatological Science · 2003 · 15 citations
    26. Effects of the anti-androgen finasteride on 5alpha-reductase activity in human gingival fibroblasts in response to minocycline Journal of Clinical Periodontology · 1998 · 15 citations
    27. Inhibition of steroid 5 alpha-reductase with finasteride: sleep-related erections, potency, and libido in healthy men. The Journal of Clinical Endocrinology and Metabolism · 1995 · 15 citations
    28. Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2 Biology · 2021 · 14 citations
    29. Efficacy and safety of Finasteride (5 alpha-reductase inhibitor) monotherapy in patients with benign prostatic hyperplasia: A critical review of the literature Archivio Italiano di Urologia e Andrologia · 2020 · 14 citations
    30. Steroid 5α-reductase 2 deficiency leads to reduced dominance-related and impulse-control behaviors Psychoneuroendocrinology · 2018 · 14 citations