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    Research 421–450 of 1000+

    1. 5α-Reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia The Year book of endocrinology · 2008
    2. Study on genetic polymorphisms of androgen receptor gene and 5α-reductase genes of Han men with androgenetic alopecia in the Eastern China Chinese Journal of Dermatology · 2006
    3. 5α-Reductase Inhibitors in the Treatment of Androgenetic Alopecia International Journal of Cosmetic Surgery and Aesthetic Dermatology · 2001
    4. A quantitative hair growth assessment in female androgenetic alopecia during one year, and its modulation by a topical 5?-reductase inhibitor Journal of The European Academy of Dermatology and Venereology · 1998
    5. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011 · 218 citations
    6. GhDET2, a steroid 5α‐reductase, plays an important role in cotton fiber cell initiation and elongation The Plant Journal · 2007 · 193 citations
    7. A New Look at the 5?-Reductase Inhibitor Finasteride Cns Drug Reviews · 2006 · 137 citations
    8. Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor Journal of the American Chemical Society · 1996 · 136 citations
    9. The 5α-Recluctase System and Its Inhibitors Dermatology · 1996 · 124 citations
    10. Evidence of Heterogeneity and Quantitative Differences of the Type 1 5α-Reductase Expression in Cultured Human Skin Cells – Evidence of its Presence in Melanocytes Journal of Investigative Dermatology · 1998 · 83 citations
    11. 5-Alpha Reductase Inhibitors and Erectile Dysfunction: The Connection The Journal of Sexual Medicine · 2008 · 78 citations
    12. Comparison of Finasteride (Proscar®) and Serenoa repens (Permixon®) in the Inhibition of 5-Alpha Reductase in Healthy Male Volunteers European Urology · 1994 · 73 citations
    13. Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders Current Pharmaceutical Design · 2011 · 72 citations
    14. Effects of 5-alpha reductase inhibitors on erectile function, sexual desire and ejaculation Expert Opinion on Drug Safety · 2012 · 71 citations
    15. Aldo-Keto Reductase (AKR) 1C3 inhibitors: a patent review Expert opinion on therapeutic patents · 2017 · 70 citations
    16. Finasteride: A slow-binding 5.alpha.-reductase inhibitor Biochemistry · 1993 · 70 citations
    17. A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-<i>α</i>-Reductase in the Treatment of Androgenetic Alopecia Journal of Alternative and Complementary Medicine · 2002 · 68 citations
    18. Effects of finasteride, a type 2 5-alpha reductase inhibitor, on fetal development in the rhesus monkey (Macaca mulatta) Teratology · 1997 · 67 citations
    19. A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-<i>α</i>-Reductase in the Treatment of Androgenetic Alopecia Journal of Alternative and Complementary Medicine · 2002 · 65 citations
    20. The effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness. The Journal of Clinical Endocrinology and Metabolism · 1994 · 59 citations
    21. The biochemical and phenotypic characterization of females homozygous for 5 alpha-reductase-2 deficiency. The Journal of Clinical Endocrinology & Metabolism · 1995 · 54 citations
    22. 5 alpha-reductase-2 gene mutations in the Dominican Republic. The Journal of Clinical Endocrinology & Metabolism · 1996 · 53 citations
    23. LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1. Proceedings of the National Academy of Sciences of the United States of America · 1993 · 53 citations
    24. Effects of Ginseng Rhizome and Ginsenoside Ro on Testosterone 5α-Reductase and Hair Re-growth in Testosterone-treated Mice Phytotherapy Research · 2011 · 51 citations
    25. The effect of spironolactone on genital skin 5α-reductase activity 1985 · 50 citations
    26. Selective non-steroidal inhibitors of 5α-reductase type 1 2004 · 49 citations
    27. Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex Journal of Biological Chemistry · 2009 · 47 citations
    28. 5 Alpha-reductase inhibitors: whatʼs new? Current opinion in urology · 2003 · 47 citations
    29. Clinical dose ranging studies with finasteride, a type 2 5α-reductase inhibitor, in men with male pattern hair loss Journal of The American Academy of Dermatology · 1999 · 46 citations
    30. Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride Hormone Molecular Biology and Clinical Investigation · 2010 · 45 citations