9 citations
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October 1946 in “Experimental biology and medicine” This study reported that supplementation with inositol, biotin, cystine, or methionine prevented hair loss in rats fed soybean oil meal, with cystine and methionine also significantly increasing growth rates.
1 citations
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January 2019 in “Journal of pharmacy & pharmacognosy research” This study found that a 2.5% flavonoid-rich extract of Equisetum hyemale promoted hair growth in a rat model of chemically-induced alopecia, showing results comparable to 5% minoxidil.
16 citations
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January 2020 in “Diabetes” In this study using diabetic rat models, the combination of AMD3100 and low-dose FK506 reduced wound healing time and improved microcirculation in diabetic foot ulcers, indicating a promising new systemic therapy.
10 citations
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January 1987 in “PubMed” This study found that triiodothyronine and epidermal growth factor differentially affected craniofacial development in neonatal rats, with various impacts on hair growth direction, incisor eruption, and ear and eyelid development.
9 citations
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April 2019 in “Molecules” This study found that a blackcurrant extract with phytoestrogen activity increased hair number and stem cell marker expression in a menopausal rat model, suggesting a potential benefit for hair loss.
7 citations
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May 2017 in “Behavioural brain research” This study found that manipulating neuroactive steroids during early development stages in male rats influences alcohol-induced locomotor sensitivity, suggesting their role in addiction vulnerability.
7 citations
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January 1998 in “EXPERIMENTAL ANIMALS” This study found no significant differences in lectinhistochemical characteristics of the dorsal skin epidermis between hypotrichotic WBN/Ila-Ht rats and Wistar rats, except for varying lectin binding intensity.
6 citations
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January 2021 in “International Journal of Molecular Sciences” This study suggests that finasteride treatment in male rats can lead to changes in liver carbohydrate metabolism and may result in metabolic disruptions and liver steatosis in their offspring.
4 citations
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September 2020 in “Open Access Macedonian Journal of Medical Sciences” This study concluded that a single injection of platelet-rich plasma can enhance wound healing in both diabetic and non-diabetic oral mucosal tissues in rats.
4 citations
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March 2019 in “Journal of Pure and Applied Microbiology” This study investigated the anti-inflammatory effects of a 940nm diode laser in Wistar rats with carrageenan-induced arthritis and found that a 74J/cm² energy density significantly reduced edema and restored function, whereas 171J/cm² neared thermal exposure limits for the skin.
1 citations
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October 2021 in “Bioactive compounds in health and disease” This study found that anthocyanins from Hibiscus rosa-sinensis petals reduced oxidative stress and increased antioxidant enzyme activity in the livers of streptozotocin-induced diabetic rats.
1 citations
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June 2016 in “Yāftah/hā-yi nuvīn dar ̒ulūm-i zīstī” This study found that sheep testis extract significantly improved wound healing and hair follicle growth in rats, suggesting it may be a promising candidate for clinical wound healing research.
December 2024 in “Journal of Applied Toxicology” This study evaluated the potential toxicity of oral dihydroartemisinin in SD rats, finding that female rats experienced greater toxic effects than males, particularly at higher doses, but these effects were reversible after a 4-week recovery period.
December 2023 in “International Journal of Health and Pharmaceutical” This study found that a mixture of 80% coconut oil and 20% candlenut oil effectively stimulated hair development in Wistar rats, which may be attributed to the high lauric acid content in coconut oil.
May 2023 in “Advancements in Homeopathic Research” This study investigated the effectiveness of a botanical formulation, Zauberӧl®, on testosterone-induced alopecia in Wistar rats, focusing on ingredients such as Arnica montana and Hibiscus Rosa sinensis. Results are not reported in the abstract.
July 2022 in “Zenodo (CERN European Organization for Nuclear Research)” In this animal study, methanolic extract of *Cordia plathytyrsa* increased testosterone synthesis in male rats but had limited effects on metabolic parameters, while *Piptadeniastrum africanum* raised triglycerides and both extracts did not cause oxidative stress.
April 2019 in “Majalah Obat Tradisional” This study found that adding menthol to Phyllanthus niruri ethanol extract gel enhanced hair growth and thickness in rats.
This study found that applying topical cinnamon essential oil on male wistar rats increased hair length and hair follicle diameter similarly to 2% minoxidil over 30 days.
April 2017 in “The journal of sexual medicine” This study investigated the effects of 5-alpha-reductase inhibitors on penile histomorphometry in both normotensive and hypertensive rats, reporting no significant changes between treated and untreated groups.
April 2017 in “The Journal of urology/The journal of urology” This study found that Sonic Hedgehog protein treatment enhanced the sprouting and regeneration of pelvic ganglia and cavernous nerves after injury, with localization of delivery affecting outcomes.
October 2013 in “Journal of Medicinal Plants Research” This study found that a local herbal cleanser significantly increased hair follicle count and anagen phase induction in Wistar rats, indicating potential hair growth benefits without apparent skin toxicity.
In this study, rhKGF2 significantly promoted hair regeneration and enhanced the formation and maturation of hair follicles in experimental bald rats, suggesting potential clinical application.
January 2011 in “Der Pharmacia Lettre” In this study, pig oil was found to significantly promote hair growth in Wister rats, performing better than the standard Minoxidil treatment from the 15th day onward.
July 2008 in “Planta Medica” This study found that Acanthus montanus leaves' aqueous extract is a developmental toxicant in rats, leading to several adverse effects on offspring when used during pregnancy.
This review discusses the immune-mediated mechanism behind alopecia areata, highlighting similarities between the condition in humans and animals, and reports no new clinical results.
This study suggests that the negative impact of high-dose Finasteride on male reproductive function may be mitigated by concurrent administration with TU.
January 2023 in “International journal of research publications” According to this study, rice bran oil was as effective as 2% minoxidil in improving hair growth parameters, such as VEGF expression, follicle diameter, and hair length, in Wistar rats treated for 21 days, showing potential for preventing hair thinning associated with aging.
January 2016 in “Medicinski Podmladak” This study found that finasteride led to increased anxiety-like behavior related to bright spaces in rats, but did not significantly affect open space anxiety-like behavior.
101 citations
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August 2003 in “Journal of comparative neurology” In this study, naked mole-rats demonstrated unique skin and hair follicle innervation features compared to other species, suggesting adaptations to their subterranean environment and poikilothermy.
96 citations
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January 1940 in “Journal of Endocrinology” This study on rats found that adrenalectomy was associated with increased hair loss compared to sham adrenalectomy, where one adrenal was left intact.