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Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Understanding skin structure and development helps diagnose and treat skin disorders.

Genetic defects and UV radiation cause skin damage and aging.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

The document is a detailed medical reference on skin and genetic disorders.

A patient with steroid sulfatase deficiency had a unique hair pattern and a brain malformation not previously linked to the condition.

The lotion and shampoo effectively treated scalp seborrheic dermatitis.

Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.

Topical vitamin D is useful for some skin conditions but not effective for others, and more research is needed.

Different amounts of daylight affect cashmere growth in goats by changing the activity of certain genes and molecules.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

ACBP is crucial for healthy skin in mice.

Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.

Experts met to improve care for ichthyosis patients in Spain.

The paper concludes that the 1982 criteria for diagnosing systemic lupus erythematosus need updating to improve accuracy and involve dermatologists in the process.

A severe medication reaction required long treatment and led to hair loss and thyroid issues.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.

Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Shrinking of oil glands in the skin is a key sign of hair loss linked to TNF inhibitor drugs and may improve if the treatment is stopped.

Finasteride doesn't affect erections much, but may decrease libido in men.

Fever and rash can be early signs of lupus.

Facelift surgery has evolved to focus on natural results and safety, with patient selection and postoperative care being key to success.

Hair loss can indicate brain aging and potential small vessel disease, but more research is needed to understand the clinical impact.