Dermatological Complications in Transplant Patients and Composite Tissue Allotransplant Pathology

    Emma Lanuti, M. A. Sharaf, B. Mark Keegan, Ingrid Wolf, Marco Romanelli, Phillip Ruiz, Paolo Romanelli
    TLDR Transplant patients face higher skin cancer risks due to immunosuppressive therapy, requiring careful skin health monitoring.
    The document reviewed dermatological complications in transplant patients, emphasizing the increased risk of skin cancers, especially squamous cell carcinoma, due to immunosuppressive therapy. It discussed the role of human papillomavirus and telomere length in cancer development and highlighted the importance of monitoring and managing skin health to mitigate these risks. The review also covered the pathology and management of composite tissue allotransplantation, including hand and face transplants, and proposed grading systems for skin allograft rejection, stressing the need to reduce immunosuppression to manage transplant-associated skin cancer.
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